Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   I6J14_RS06380 Genome accession   NZ_CP068057
Coordinates   1267950..1268432 (-) Length   160 a.a.
NCBI ID   WP_003049584.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1262950..1273432
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS06345 (I6J14_06345) - 1263153..1263665 (-) 513 WP_003049697.1 cysteine hydrolase family protein -
  I6J14_RS06350 (I6J14_06350) yqeK 1263666..1264259 (-) 594 WP_003049694.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  I6J14_RS06355 (I6J14_06355) - 1264256..1264888 (-) 633 WP_003049693.1 nicotinate-nucleotide adenylyltransferase -
  I6J14_RS06360 (I6J14_06360) yhbY 1264957..1265265 (-) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  I6J14_RS06365 (I6J14_06365) yqeH 1265294..1266412 (-) 1119 WP_003049692.1 ribosome biogenesis GTPase YqeH -
  I6J14_RS06370 (I6J14_06370) - 1266412..1266939 (-) 528 WP_003049691.1 YqeG family HAD IIIA-type phosphatase -
  I6J14_RS06375 (I6J14_06375) - 1267077..1267804 (+) 728 Protein_1271 IS30 family transposase -
  I6J14_RS06380 (I6J14_06380) comX/sigX/comX2/sigX2 1267950..1268432 (-) 483 WP_003049584.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19124.95 Da        Isoelectric Point: 9.0893

>NTDB_id=458683 I6J14_RS06380 WP_003049584.1 1267950..1268432(-) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MSLETREVFEKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVRLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQ
KRQFDKMAYEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSEADRKQFQALVRGERFKGRQALLRKVRPYFSGFDQG

Nucleotide


Download         Length: 483 bp        

>NTDB_id=458683 I6J14_RS06380 WP_003049584.1 1267950..1268432(-) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGTCGTTAGAGACAAGGGAGGTTTTTGAGAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACCTACAGTT
GTGGGAGACGGATGACTGGTTACAAGAGGGGCATTTGGTTTTAGTGAGGTTGTTGGAACGTCACCCAGAATTAGTAGGAG
ATGAGGCTCGCTTGTATCGGTATTTTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAG
AAACGCCAGTTTGATAAGATGGCTTATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGTGGGTTATGGTTGGA
TGATTATGTGGCTTATCGGGAGGTTTTGGTTCAGGTGGAGGAGGCCTTAAGTGAAGCGGATCGGAAGCAGTTTCAGGCTT
TGGTGAGAGGGGAACGGTTTAAGGGGCGTCAGGCTTTACTTAGGAAGGTTCGTCCTTACTTTAGTGGGTTTGACCAAGGG
TGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

75.472

99.375

0.75
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

75.472

99.375

0.75
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

74.843

99.375

0.744
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

74.843

99.375

0.744
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

74.214

99.375

0.738
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

74.214

99.375

0.738
  comX/sigX Streptococcus mutans UA159

49.342

95

0.469
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

93.75

0.456
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

46.405

95.625

0.444
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.098

95.625

0.431
  comX/comX1 Streptococcus pneumoniae Rx1

44.737

95

0.425
  comX/comX2 Streptococcus pneumoniae TIGR4

44.737

95

0.425
  comX/comX1 Streptococcus pneumoniae TIGR4

44.737

95

0.425
  comX/comX2 Streptococcus pneumoniae Rx1

44.737

95

0.425
  comX/comX2 Streptococcus pneumoniae D39

44.737

95

0.425
  comX/comX1 Streptococcus pneumoniae D39

44.737

95

0.425
  comX/comX2 Streptococcus pneumoniae R6

44.737

95

0.425
  comX/comX1 Streptococcus pneumoniae R6

44.737

95

0.425
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

43.791

95.625

0.419
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419
  comX Streptococcus sobrinus strain NIDR 6715-7

44.079

95

0.419
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419
  comX Streptococcus thermophilus LMG 18311

43.709

94.375

0.413
  comX Streptococcus thermophilus LMD-9

43.709

94.375

0.413
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.137

95.625

0.412
  comX/sigX Streptococcus salivarius strain HSISS4

41.722

94.375

0.394
  comX Streptococcus salivarius SK126

41.722

94.375

0.394
  comX/sigX Streptococcus suis D9

38.71

96.875

0.375
  comX/sigX Streptococcus suis isolate S10

38.71

96.875

0.375
  comX/sigX Streptococcus suis P1/7

38.71

96.875

0.375