Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   GE021_RS01875 Genome accession   NZ_CP053792
Coordinates   366998..367480 (+) Length   160 a.a.
NCBI ID   WP_125075072.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_1     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 361998..372480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS01870 (GE021_001870) - 365292..366818 (-) 1527 WP_125075051.1 IS1182 family transposase -
  GE021_RS01875 (GE021_001875) comX/sigX/comX2/sigX2 366998..367480 (+) 483 WP_125075072.1 competence protein ComX Regulator
  GE021_RS01880 (GE021_001880) truA 368800..369549 (+) 750 WP_125074722.1 tRNA pseudouridine(38-40) synthase TruA -
  GE021_RS01885 (GE021_001885) - 369539..370306 (+) 768 WP_125074721.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  GE021_RS01890 (GE021_001890) - 370293..370763 (+) 471 WP_125074720.1 ECF transporter S component -
  GE021_RS01895 (GE021_001895) - 370776..371339 (+) 564 WP_164407353.1 TIGR01440 family protein -
  GE021_RS01900 (GE021_001900) - 371409..372254 (-) 846 WP_003046591.1 mechanosensitive ion channel family protein -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19362.20 Da        Isoelectric Point: 6.5020

>NTDB_id=447255 GE021_RS01875 WP_125075072.1 366998..367480(+) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_77_1]
MSIETGVVFEKVKPIILKLKRHYYIQLWEREDWLQEGYLILVSLLEQHPELLWEDERLYRYFKTKFSSYLKDVLRQQESQ
KRQFHKMAYEEIGDVAHAIPSGGLWLDDYVAYREVVEALEGQLSEEERLQFQALVRGERFKGRQALLRKLRPYFEGFERS

Nucleotide


Download         Length: 483 bp        

>NTDB_id=447255 GE021_RS01875 WP_125075072.1 366998..367480(+) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_77_1]
ATGTCGATAGAGACAGGAGTAGTGTTTGAGAAGGTGAAACCCATTATCTTGAAGTTGAAGCGTCATTATTATATTCAATT
GTGGGAGAGGGAGGATTGGTTACAGGAAGGGTATTTGATATTGGTGAGTCTCCTAGAGCAGCATCCTGAATTACTTTGGG
AAGACGAACGGTTGTATCGTTATTTTAAGACTAAGTTTTCATCGTATTTGAAGGATGTCTTGCGTCAGCAAGAAAGTCAG
AAGCGTCAGTTTCATAAAATGGCTTATGAGGAGATAGGTGATGTAGCACATGCGATTCCATCAGGTGGGTTATGGTTGGA
TGATTACGTGGCCTATAGGGAGGTGGTTGAGGCGTTAGAAGGGCAGTTGAGTGAAGAGGAGCGGTTACAGTTTCAGGCCT
TGGTGAGAGGGGAACGGTTTAAGGGAAGGCAGGCCTTGCTTAGGAAGTTGCGTCCTTATTTTGAGGGATTTGAGAGAAGT
TAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

78.981

98.125

0.775
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

78.981

98.125

0.775
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

78.344

98.125

0.769
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

78.344

98.125

0.769
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

77.707

98.125

0.762
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

77.707

98.125

0.762
  comX/sigX Streptococcus mutans UA159

53.947

95

0.512
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

93.75

0.456
  comX Streptococcus thermophilus LMG 18311

44.371

94.375

0.419
  comX Streptococcus thermophilus LMD-9

44.371

94.375

0.419
  comX Streptococcus sobrinus strain NIDR 6715-7

43.709

94.375

0.413
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

43.046

94.375

0.406
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

43.046

94.375

0.406
  comX Streptococcus salivarius SK126

42.384

94.375

0.4
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

42.384

94.375

0.4
  comX/sigX Streptococcus salivarius strain HSISS4

42.384

94.375

0.4
  comX/comX2 Streptococcus pneumoniae Rx1

42

93.75

0.394
  comX/comX1 Streptococcus pneumoniae Rx1

42

93.75

0.394
  comX/comX2 Streptococcus pneumoniae D39

42

93.75

0.394
  comX/comX1 Streptococcus pneumoniae D39

42

93.75

0.394
  comX/comX2 Streptococcus pneumoniae R6

42

93.75

0.394
  comX/comX1 Streptococcus pneumoniae R6

42

93.75

0.394
  comX/comX2 Streptococcus pneumoniae TIGR4

42

93.75

0.394
  comX/comX1 Streptococcus pneumoniae TIGR4

42

93.75

0.394
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

41.06

94.375

0.388
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

41.06

94.375

0.388
  comX/sigX Streptococcus suis D9

40

93.75

0.375
  comX/sigX Streptococcus suis isolate S10

40

93.75

0.375
  comX/sigX Streptococcus suis P1/7

40

93.75

0.375
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

39.073

94.375

0.369