Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   HBA50_RS10095 Genome accession   NZ_CP050133
Coordinates   2018480..2018962 (-) Length   160 a.a.
NCBI ID   WP_045497765.1    Uniprot ID   A0A0F2CFY9
Organism   Streptococcus cristatus ATCC 51100     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2013480..2023962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS10095 (HBA50_10095) comR/comR2 2018480..2018962 (-) 483 WP_045497765.1 sigma-70 family RNA polymerase sigma factor Regulator
  HBA50_RS10100 (HBA50_10100) ftsH 2019178..2021145 (-) 1968 WP_045499856.1 ATP-dependent zinc metalloprotease FtsH -
  HBA50_RS10105 (HBA50_10105) hpt 2021163..2021705 (-) 543 WP_045499858.1 hypoxanthine phosphoribosyltransferase -
  HBA50_RS10110 (HBA50_10110) tilS 2021714..2022988 (-) 1275 WP_045499861.1 tRNA lysidine(34) synthetase TilS -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19691.24 Da        Isoelectric Point: 8.0790

>NTDB_id=430243 HBA50_RS10095 WP_045497765.1 2018480..2018962(-) (comR/comR2) [Streptococcus cristatus ATCC 51100]
MNFKERYEKVQWIVRRCARDYYVHLWESSDWEQEGMLVYHQLEESHPDISQDESRLYRYFKTKFRNHIHDILRKQESQKR
RFDRQSYEEVGTISHRLSKRELALDDLVALRSSLAAYTSKLDKEQLELYHRLLGDERFKGRKRLLRELEEYLIDFSSTVI

Nucleotide


Download         Length: 483 bp        

>NTDB_id=430243 HBA50_RS10095 WP_045497765.1 2018480..2018962(-) (comR/comR2) [Streptococcus cristatus ATCC 51100]
ATGAACTTCAAGGAACGCTATGAGAAAGTGCAGTGGATCGTCCGGCGCTGCGCACGGGATTATTATGTACATTTATGGGA
GAGTAGTGACTGGGAACAAGAAGGTATGCTGGTTTATCACCAGCTGGAAGAAAGTCATCCAGATATCAGTCAAGATGAAA
GCCGCCTCTATCGCTACTTCAAGACAAAATTTCGGAATCATATTCATGACATACTTCGCAAGCAAGAGAGCCAAAAACGC
CGCTTCGATCGTCAGTCTTATGAAGAAGTTGGAACCATTAGTCATAGACTGAGCAAGCGCGAACTAGCTTTAGATGATTT
AGTCGCTCTTCGAAGTTCGTTAGCAGCCTACACTTCCAAGTTAGACAAAGAACAACTAGAGTTATACCACCGCTTACTAG
GTGACGAACGGTTTAAGGGGCGTAAAAGACTGTTGCGAGAGTTAGAGGAATATTTAATAGACTTTAGCAGCACGGTGATA
TAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2CFY9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

56.604

99.375

0.563
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

56.604

99.375

0.563
  comX/comX1 Streptococcus pneumoniae TIGR4

51.948

96.25

0.5
  comX/comX2 Streptococcus pneumoniae TIGR4

51.948

96.25

0.5
  comX/comX2 Streptococcus pneumoniae D39

51.299

96.25

0.494
  comX/comX2 Streptococcus pneumoniae Rx1

51.299

96.25

0.494
  comX/comX1 Streptococcus pneumoniae Rx1

51.299

96.25

0.494
  comX/comX1 Streptococcus pneumoniae D39

51.299

96.25

0.494
  comX/comX2 Streptococcus pneumoniae R6

51.299

96.25

0.494
  comX/comX1 Streptococcus pneumoniae R6

51.299

96.25

0.494
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

52.055

91.25

0.475
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

52.055

91.25

0.475
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

52.055

91.25

0.475
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

52.055

91.25

0.475
  comX/sigX Streptococcus mutans UA159

48.052

96.25

0.463
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.484

95.625

0.406
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.484

95.625

0.406
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.484

95.625

0.406
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.484

95.625

0.406
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.484

95.625

0.406
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.484

95.625

0.406
  comX Streptococcus thermophilus LMG 18311

41.667

97.5

0.406
  comX Streptococcus thermophilus LMD-9

41.667

97.5

0.406
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

41.667

97.5

0.406
  comX/sigX Streptococcus suis D9

41.29

96.875

0.4
  comX/sigX Streptococcus suis isolate S10

41.29

96.875

0.4
  comX/sigX Streptococcus suis P1/7

41.29

96.875

0.4
  comX/sigX Streptococcus salivarius strain HSISS4

40.645

96.875

0.394
  comX Streptococcus salivarius SK126

40.645

96.875

0.394
  comX Streptococcus sobrinus strain NIDR 6715-7

37.662

96.25

0.362