Detailed information    

insolico Bioinformatically predicted

Overview


Name   comFC/cflB   Type   Machinery gene
Locus tag   SSUST3_RS02360 Genome accession   NC_015433
Coordinates   447243..447908 (+) Length   221 a.a.
NCBI ID   WP_004194119.1    Uniprot ID   A0A140EWV9
Organism   Streptococcus suis ST3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 426855..447250 447243..447908 flank -7


Gene organization within MGE regions


Location: 426855..447908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUST3_RS02205 (SSUST3_0431) - 426855..428012 (-) 1158 WP_013730163.1 tyrosine-type recombinase/integrase -
  SSUST3_RS02210 (SSUST3_0432) - 428209..428940 (-) 732 WP_013730164.1 hypothetical protein -
  SSUST3_RS02215 (SSUST3_0433) - 428988..429371 (-) 384 WP_013730165.1 ImmA/IrrE family metallo-endopeptidase -
  SSUST3_RS02220 (SSUST3_0434) - 429378..429926 (-) 549 WP_022540560.1 helix-turn-helix domain-containing protein -
  SSUST3_RS02225 (SSUST3_0435) - 429943..430143 (+) 201 WP_002937001.1 helix-turn-helix domain-containing protein -
  SSUST3_RS02230 (SSUST3_0436) - 430213..430539 (+) 327 WP_013730166.1 hypothetical protein -
  SSUST3_RS02235 (SSUST3_0437) - 430613..430867 (+) 255 WP_013730167.1 hypothetical protein -
  SSUST3_RS02240 (SSUST3_0438) - 430908..431156 (+) 249 WP_013730168.1 hypothetical protein -
  SSUST3_RS10610 - 431146..431298 (+) 153 WP_022540561.1 hypothetical protein -
  SSUST3_RS02245 (SSUST3_0439) - 431303..431644 (+) 342 WP_013730169.1 hypothetical protein -
  SSUST3_RS02250 (SSUST3_0440) - 431644..432123 (+) 480 WP_013730170.1 siphovirus Gp157 family protein -
  SSUST3_RS02255 (SSUST3_0441) - 432120..432365 (+) 246 WP_013730171.1 hypothetical protein -
  SSUST3_RS02260 (SSUST3_0442) - 432346..432810 (+) 465 WP_013730172.1 hypothetical protein -
  SSUST3_RS02265 (SSUST3_0443) - 432779..433951 (+) 1173 WP_013730173.1 DEAD/DEAH box helicase family protein -
  SSUST3_RS02270 (SSUST3_0444) - 433972..434292 (+) 321 WP_013730174.1 hypothetical protein -
  SSUST3_RS02275 (SSUST3_0445) - 434302..435000 (+) 699 WP_013730175.1 ERF family protein -
  SSUST3_RS02280 - 435000..435296 (+) 297 WP_022540564.1 hypothetical protein -
  SSUST3_RS02285 (SSUST3_0446) ssbA 435293..435691 (+) 399 WP_013730176.1 single-stranded DNA-binding protein Machinery gene
  SSUST3_RS02290 (SSUST3_0447) - 435702..436529 (+) 828 WP_013730177.1 bifunctional DNA primase/polymerase -
  SSUST3_RS02295 (SSUST3_0448) - 436513..437892 (+) 1380 WP_079253058.1 virulence-associated E family protein -
  SSUST3_RS10680 (SSUST3_0449) - 438270..438425 (+) 156 WP_013730179.1 DUF7204 family protein -
  SSUST3_RS02300 (SSUST3_0450) - 438422..438730 (+) 309 WP_013730180.1 DUF1372 family protein -
  SSUST3_RS02305 (SSUST3_0451) - 438732..438947 (+) 216 WP_013730181.1 hypothetical protein -
  SSUST3_RS02310 (SSUST3_0452) - 439136..439450 (+) 315 WP_013730182.1 hypothetical protein -
  SSUST3_RS02315 (SSUST3_0453) - 439523..439957 (+) 435 WP_002937915.1 DUF1492 domain-containing protein -
  SSUST3_RS02320 (SSUST3_0454) - 440054..440401 (+) 348 WP_013730183.1 HNH endonuclease -
  SSUST3_RS02325 (SSUST3_0455) - 440606..440851 (+) 246 WP_022540566.1 hypothetical protein -
  SSUST3_RS02330 (SSUST3_0456) - 440848..442113 (+) 1266 WP_013730185.1 phage portal protein -
  SSUST3_RS10685 (SSUST3_0457) - 442106..443326 (+) 1221 WP_013730186.1 hypothetical protein -
  SSUST3_RS02340 - 443331..443564 (+) 234 WP_022540567.1 hypothetical protein -
  SSUST3_RS02345 (SSUST3_0459) - 444265..444471 (-) 207 WP_041179173.1 DUF1492 domain-containing protein -
  SSUST3_RS02350 (SSUST3_0460) - 445269..445901 (-) 633 WP_004194123.1 YigZ family protein -
  SSUST3_RS02355 (SSUST3_0461) comFA/cflA 445958..447250 (+) 1293 WP_004194121.1 DEAD/DEAH box helicase Machinery gene
  SSUST3_RS02360 (SSUST3_0462) comFC/cflB 447243..447908 (+) 666 WP_004194119.1 ComF family protein Machinery gene

Sequence


Protein


Download         Length: 221 a.a.        Molecular weight: 25748.55 Da        Isoelectric Point: 8.2726

>NTDB_id=40538 SSUST3_RS02360 WP_004194119.1 447243..447908(+) (comFC/cflB) [Streptococcus suis ST3]
MSNCLLCGQAMKNKTRFSDLIFFSKEKSGICEECFSTFEEIAEQHCPHCYKNGESESCKDCQYWQNQGKPVVHTALYQYN
QAMAHYFSRYKFQGDYVLRNIFAKKLRIALSQFPDYTIVPIPISQKRLSERGFNQVEGLLDATNIPYQSLLGKYESQKQS
SKNRAERLEAKQMFYLLDEKEVPEKILLFDDIYTTGATIQLAVELFMKIGRKEIKTFSLTR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=40538 SSUST3_RS02360 WP_004194119.1 447243..447908(+) (comFC/cflB) [Streptococcus suis ST3]
ATGTCTAATTGTCTATTGTGCGGTCAAGCTATGAAAAATAAAACAAGATTTTCAGATCTCATCTTCTTTAGTAAAGAAAA
ATCGGGCATCTGTGAAGAATGTTTTTCGACTTTTGAGGAAATAGCAGAGCAACACTGTCCACATTGTTATAAAAATGGAG
AATCGGAAAGTTGCAAGGATTGTCAGTACTGGCAGAATCAAGGGAAACCAGTTGTCCACACAGCTTTGTACCAATATAAT
CAAGCGATGGCACATTATTTTAGTCGCTACAAATTTCAAGGAGACTATGTTTTAAGAAATATTTTTGCTAAAAAGCTTAG
AATAGCGTTAAGCCAATTTCCTGACTACACAATTGTTCCCATACCAATTAGTCAAAAACGACTATCAGAACGCGGTTTTA
ATCAAGTGGAAGGACTTTTGGATGCTACAAATATTCCTTATCAGTCCCTTCTTGGAAAGTATGAAAGCCAAAAACAATCA
TCTAAAAATCGTGCAGAGAGACTAGAAGCAAAACAGATGTTCTATCTATTAGATGAAAAAGAAGTGCCAGAAAAAATATT
ATTATTCGACGATATATATACAACAGGAGCCACAATCCAACTTGCTGTAGAACTTTTCATGAAAATTGGTAGGAAAGAAA
TCAAAACATTTTCACTAACACGATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A140EWV9

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

49.083

98.643

0.484

  comFC/cflB Streptococcus pneumoniae TIGR4

49.083

98.643

0.484

  comFC/cflB Streptococcus pneumoniae Rx1

49.083

98.643

0.484

  comFC/cflB Streptococcus pneumoniae D39

49.083

98.643

0.484

  comFC/cflB Streptococcus pneumoniae R6

49.083

98.643

0.484

  comFC/cflB Streptococcus mitis NCTC 12261

49.083

98.643

0.484


Multiple sequence alignment