Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   SOR_RS00955 Genome accession   NC_015291
Coordinates   184304..184777 (+) Length   157 a.a.
NCBI ID   WP_001049309.1    Uniprot ID   A0A1H0UHR1
Organism   Streptococcus oralis Uo5     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 179304..189777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS00930 (SOR_0189) - 180041..180916 (-) 876 WP_013670154.1 RluA family pseudouridine synthase -
  SOR_RS00935 (SOR_0190) pbp2a 181003..183198 (+) 2196 WP_000762588.1 penicillin-binding protein PBP2A -
  SOR_RS00940 (SOR_0191) rpmG 183251..183403 (+) 153 WP_001809375.1 50S ribosomal protein L33 -
  SOR_RS00945 (SOR_0192) secE 183413..183589 (+) 177 WP_000505776.1 preprotein translocase subunit SecE -
  SOR_RS00950 (SOR_0193) nusG 183647..184183 (+) 537 WP_000376732.1 transcription termination/antitermination protein NusG -
  SOR_RS00955 (SOR_0194) comX/comX2 184304..184777 (+) 474 WP_001049309.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19279.17 Da        Isoelectric Point: 8.1389

>NTDB_id=40176 SOR_RS00955 WP_001049309.1 184304..184777(+) (comX/comX2) [Streptococcus oralis Uo5]
MNLKDLYEESKGIVHKCRKDYHLHLWEKEDWNQEGMLCLYELVSCNPELLEGERHRLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSMEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=40176 SOR_RS00955 WP_001049309.1 184304..184777(+) (comX/comX2) [Streptococcus oralis Uo5]
ATGAATCTAAAAGATTTATATGAAGAAAGTAAGGGAATCGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGAATCAGGAAGGCATGTTATGTCTGTATGAGCTGGTGAGTTGCAACCCAGAGTTACTAGAGGGGGAGC
GCCATCGACTTTATGTCTGCTTTAAAACAAAGTTTAGAAATCGTATCCTAGATTACATCCGTAAACAGGAAAGCCACAAG
CGCCGTTTTGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGCCATCGTCTAGGAGAGAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAATTACAAATCAAAGCAGAGTATGGAAAAACAAGAATTAATAGACCGTCTAA
TGGGAGGAGAAGTCTTTAGAGGACGTAAAGCTCTCCTGAGAGAACTTTCCCTTATCTTTTCAGAATTTCGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1H0UHR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX1 Streptococcus pneumoniae Rx1

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae D39

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae D39

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae R6

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae R6

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae Rx1

64.286

98.089

0.631
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

63.636

98.089

0.624
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

62.987

98.089

0.618
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

62.338

98.089

0.611
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

62.338

98.089

0.611
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comX/sigX Streptococcus mutans UA159

46.711

96.815

0.452
  comX/sigX Streptococcus suis isolate S10

40.764

100

0.408
  comX/sigX Streptococcus suis D9

40.764

100

0.408
  comX/sigX Streptococcus suis P1/7

40.764

100

0.408
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX Streptococcus thermophilus LMD-9

40

95.541

0.382
  comX/sigX Streptococcus salivarius strain HSISS4

40

95.541

0.382
  comX Streptococcus thermophilus LMG 18311

40

95.541

0.382
  comX Streptococcus salivarius SK126

40

95.541

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

41.958

91.083

0.382
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.342

100

0.376

Multiple sequence alignment