Detailed information NTG0394594

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: GE021_RS02125
• Genome accession: NZ_CP053792
• Coordinates: 419782..420264 (+)
• Length: 160 a.a.
• NCBI ID: WP_125075072.1
• Uniprot ID: A0A3P5Y6G7
• Organism: Streptococcus canis strain HL_77_1
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 414782..425264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE021_RS02120 (GE021_002120)	-	418134..419660 (+)	1527	WP_125075051.1	IS1182 family transposase	-
GE021_RS02125 (GE021_002125)	comX/sigX/comX2/sigX2	419782..420264 (+)	483	WP_125075072.1	competence protein ComX	Regulator
GE021_RS02130 (GE021_002130)	-	420389..421321 (-)	933	Protein_380	IS30 family transposase	-
GE021_RS02135 (GE021_002135)	-	421512..422039 (+)	528	WP_164406360.1	YqeG family HAD IIIA-type phosphatase	-
GE021_RS02140 (GE021_002140)	yqeH	422039..423157 (+)	1119	WP_125074749.1	ribosome biogenesis GTPase YqeH	-
GE021_RS02145 (GE021_002145)	yhbY	423184..423492 (+)	309	WP_125074748.1	ribosome assembly RNA-binding protein YhbY	-
GE021_RS02150 (GE021_002150)	-	423571..424203 (+)	633	WP_125074747.1	nicotinate-nucleotide adenylyltransferase	-
GE021_RS02155 (GE021_002155)	yqeK	424200..424793 (+)	594	WP_125074746.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
GE021_RS11210	-	424950..425234 (+)	285	WP_254388114.1	isochorismatase family protein	-

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19362.20 Da
• Isoelectric Point: 6.5020

>NTDB_id=394594 GE021_RS02125 WP_125075072.1 419782..420264(+) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_77_1]
MSIETGVVFEKVKPIILKLKRHYYIQLWEREDWLQEGYLILVSLLEQHPELLWEDERLYRYFKTKFSSYLKDVLRQQESQ
KRQFHKMAYEEIGDVAHAIPSGGLWLDDYVAYREVVEALEGQLSEEERLQFQALVRGERFKGRQALLRKLRPYFEGFERS

Nucleotide

• Length: 483 bp

>NTDB_id=394594 GE021_RS02125 WP_125075072.1 419782..420264(+) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_77_1]
ATGTCGATAGAGACAGGAGTAGTGTTTGAGAAGGTGAAACCCATTATCTTGAAGTTGAAGCGTCATTATTATATTCAATT
GTGGGAGAGGGAGGATTGGTTACAGGAAGGGTATTTGATATTGGTGAGTCTCCTAGAGCAGCATCCTGAATTACTTTGGG
AAGACGAACGGTTGTATCGTTATTTTAAGACTAAGTTTTCATCGTATTTGAAGGATGTCTTGCGTCAGCAAGAAAGTCAG
AAGCGTCAGTTTCATAAAATGGCTTATGAGGAGATAGGTGATGTAGCACATGCGATTCCATCAGGTGGGTTATGGTTGGA
TGATTACGTGGCCTATAGGGAGGTGGTTGAGGCGTTAGAAGGGCAGTTGAGTGAAGAGGAGCGGTTACAGTTTCAGGCCT
TGGTGAGAGGGGAACGGTTTAAGGGAAGGCAGGCCTTGCTTAGGAAGTTGCGTCCTTATTTTGAGGGATTTGAGAGAAGT
TAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A3P5Y6G7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	78.981	98.125	0.775
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	78.981	98.125	0.775
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	78.344	98.125	0.769
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	78.344	98.125	0.769
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	77.707	98.125	0.762
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	77.707	98.125	0.762
comX/sigX	Streptococcus mutans UA159	53.947	95	0.512
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.667	93.75	0.456
comX	Streptococcus thermophilus LMG 18311	44.371	94.375	0.419
comX	Streptococcus thermophilus LMD-9	44.371	94.375	0.419
comX	Streptococcus sobrinus strain NIDR 6715-7	43.709	94.375	0.413
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	43.046	94.375	0.406
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	43.046	94.375	0.406
comX	Streptococcus salivarius SK126	42.384	94.375	0.4
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	42.384	94.375	0.4
comX/sigX	Streptococcus salivarius strain HSISS4	42.384	94.375	0.4
comX/comX2	Streptococcus pneumoniae Rx1	42	93.75	0.394
comX/comX1	Streptococcus pneumoniae Rx1	42	93.75	0.394
comX/comX2	Streptococcus pneumoniae D39	42	93.75	0.394
comX/comX1	Streptococcus pneumoniae D39	42	93.75	0.394
comX/comX2	Streptococcus pneumoniae R6	42	93.75	0.394
comX/comX1	Streptococcus pneumoniae R6	42	93.75	0.394
comX/comX2	Streptococcus pneumoniae TIGR4	42	93.75	0.394
comX/comX1	Streptococcus pneumoniae TIGR4	42	93.75	0.394
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	41.06	94.375	0.388
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	41.06	94.375	0.388
comX/sigX	Streptococcus suis D9	40	93.75	0.375
comX/sigX	Streptococcus suis isolate S10	40	93.75	0.375
comX/sigX	Streptococcus suis P1/7	40	93.75	0.375
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	39.073	94.375	0.369