Detailed information NTG0375028

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: FPL13_RS08160
• Genome accession: NZ_CP041968
• Coordinates: 1678667..1679140 (-)
• Length: 157 a.a.
• NCBI ID: WP_192208567.1
• Uniprot ID: A0A7L8W6L6
• Organism: Streptococcus sp. KS 6
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1679975..1681360	1678667..1679140	flank	835

Gene organization within MGE regions

Location: 1678667..1681360

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPL13_RS08160 (FPL13_08260)	comR/comR2	1678667..1679140 (-)	474	WP_192208567.1	sigma-70 family RNA polymerase sigma factor	Regulator
FPL13_RS10015	-	1679492..1679629 (+)	138	Protein_1603	IS982 family transposase	-
FPL13_RS08175 (FPL13_08275)	-	1679975..1681360 (+)	1386	WP_192208576.1	IS1182 family transposase	-

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19262.10 Da
• Isoelectric Point: 7.9948

>NTDB_id=375028 FPL13_RS08160 WP_192208567.1 1678667..1679140(-) (comR/comR2) [Streptococcus sp. KS 6]
MEFKELYGKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYQLVSRYPQLVETESQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDHLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide

• Length: 474 bp

>NTDB_id=375028 FPL13_RS08160 WP_192208567.1 1678667..1679140(-) (comR/comR2) [Streptococcus sp. KS 6]
ATGGAGTTCAAGGAGTTGTATGGGAAGGTAAGGGGGATTGTATTAAAGTGCCGTCGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGACCAAGAGGGCATGTTAGTACTCTATCAGTTGGTAAGTCGCTATCCGCAGCTGGTAGAGACAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTGGACATCCTCCGTAAACAGGAAAGCCAAAAACGC
AAACTCGATCGTCAAGCTTATGAAGAAGTGAGCGAGATAGGTCACAAGCTCAGCCTGAAAGAGTTGTATCTGGATGAATT
GGTGATTCTCCGAGACCATCTAAAGAGCTATCAAGCTCAACTGAGTCCAGAGAAACAAGAGCAGTACGAGCGCTTACTAG
CTGATGAACGTTTCAAAGGCCGCCAAGCCATGATTCGAGAATTAAGAGCCTACTTAAAGGACTATAGCGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A7L8W6L6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	60.256	99.363	0.599
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	60.256	99.363	0.599
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	55.195	98.089	0.541
comX/comX2	Streptococcus pneumoniae Rx1	54.545	98.089	0.535
comX/comX1	Streptococcus pneumoniae Rx1	54.545	98.089	0.535
comX/comX2	Streptococcus pneumoniae D39	54.545	98.089	0.535
comX/comX1	Streptococcus pneumoniae D39	54.545	98.089	0.535
comX/comX2	Streptococcus pneumoniae R6	54.545	98.089	0.535
comX/comX1	Streptococcus pneumoniae R6	54.545	98.089	0.535
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	54.545	98.089	0.535
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae TIGR4	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae TIGR4	53.896	98.089	0.529
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	53.247	98.089	0.522
comX/sigX	Streptococcus mutans UA159	48.718	99.363	0.484
comX/sigX	Streptococcus suis D9	47.097	98.726	0.465
comX/sigX	Streptococcus suis isolate S10	47.097	98.726	0.465
comX/sigX	Streptococcus suis P1/7	47.097	98.726	0.465
comX	Streptococcus salivarius SK126	43.506	98.089	0.427
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.308	99.363	0.42
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.308	99.363	0.42
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.308	99.363	0.42
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.308	99.363	0.42
comX/sigX	Streptococcus salivarius strain HSISS4	42.857	98.089	0.42
comX	Streptococcus thermophilus LMG 18311	42.857	98.089	0.42
comX	Streptococcus thermophilus LMD-9	42.857	98.089	0.42
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	38.462	99.363	0.382
comX	Streptococcus sobrinus strain NIDR 6715-7	39.216	97.452	0.382