Detailed information NTG0367192

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: FDP16_RS00090
• Genome accession: NZ_CP040798
• Coordinates: 17816..18301 (+)
• Length: 161 a.a.
• NCBI ID: WP_002928633.1
• Uniprot ID: A0A428AQ86
• Organism: Streptococcus sanguinis strain CGMH058
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	17145..17618	17816..18301	flank	198

Gene organization within MGE regions

Location: 17145..18301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FDP16_RS00085 (FDP16_00090)	tnpA	17145..17618 (+)	474	WP_175859346.1	IS200/IS605 family transposase	-
FDP16_RS00090 (FDP16_00095)	comR/comR2	17816..18301 (+)	486	WP_002928633.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 19964.85 Da
• Isoelectric Point: 9.1020

>NTDB_id=367192 FDP16_RS00090 WP_002928633.1 17816..18301(+) (comR/comR2) [Streptococcus sanguinis strain CGMH058]
MDFRATYEKVKWIVWKCKKDYYIHLWEHSDWEQEGMLVLYELLLKEKGIENDEEKLYRYFKTKFRNHIHDKIRKQESQKR
KLDRQPYEEVSEIGHRLKSKELFLDELVAFREAIDNYKRTLDDVGLDNYQRLMSNERFKGRRAMLKDLKNHLKDFQDNTI
L

Nucleotide

• Length: 486 bp

>NTDB_id=367192 FDP16_RS00090 WP_002928633.1 17816..18301(+) (comR/comR2) [Streptococcus sanguinis strain CGMH058]
ATGGATTTTAGAGCTACTTATGAGAAGGTGAAATGGATAGTTTGGAAGTGTAAGAAAGATTACTATATTCATTTGTGGGA
ACATAGTGATTGGGAGCAAGAAGGAATGTTAGTTTTATACGAACTTCTGCTTAAAGAAAAAGGGATTGAAAACGATGAGG
AAAAACTCTATCGTTATTTCAAAACAAAATTCAGAAATCATATACATGATAAAATTCGTAAACAAGAAAGCCAAAAGCGC
AAATTGGACCGCCAGCCTTATGAAGAAGTGAGTGAGATTGGACATCGACTAAAATCAAAAGAGCTGTTTCTAGATGAGTT
AGTTGCCTTCAGAGAAGCGATTGACAATTATAAAAGAACTCTTGATGATGTTGGATTGGATAATTATCAGAGGTTGATGA
GCAACGAGCGCTTTAAAGGAAGAAGAGCTATGCTCAAAGATTTAAAAAATCACTTAAAAGATTTTCAAGACAATACGATT
TTATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A428AQ86

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comX/comX2	Streptococcus pneumoniae TIGR4	50.327	95.031	0.478
comX/comX1	Streptococcus pneumoniae TIGR4	50.327	95.031	0.478
comX/sigX	Streptococcus suis isolate S10	49.359	96.894	0.478
comX/sigX	Streptococcus suis D9	49.359	96.894	0.478
comX/sigX	Streptococcus suis P1/7	49.359	96.894	0.478
comX/comX2	Streptococcus pneumoniae Rx1	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae Rx1	49.673	95.031	0.472
comX/comX2	Streptococcus pneumoniae D39	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae D39	49.673	95.031	0.472
comX/comX2	Streptococcus pneumoniae R6	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae R6	49.673	95.031	0.472
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	47.771	97.516	0.466
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	47.134	97.516	0.46
comX/sigX	Streptococcus mutans UA159	47.436	96.894	0.46
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	46.497	97.516	0.453
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	45.223	97.516	0.441
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	43.871	96.273	0.422
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	43.871	96.273	0.422
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	43.871	96.273	0.422
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	43.871	96.273	0.422
comX	Streptococcus sobrinus strain NIDR 6715-7	41.212	100	0.422
comX	Streptococcus thermophilus LMD-9	42.949	96.894	0.416
comX	Streptococcus thermophilus LMG 18311	42.949	96.894	0.416
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.405	98.137	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.405	98.137	0.416
comX/sigX	Streptococcus salivarius strain HSISS4	41.176	95.031	0.391
comX	Streptococcus salivarius SK126	41.176	95.031	0.391
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.49	97.516	0.385