Detailed information NTG0362621

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: FD735_RS00970
• Genome accession: NZ_CP040231
• Coordinates: 170514..170987 (+)
• Length: 157 a.a.
• NCBI ID: WP_049478144.1
• Uniprot ID: A0A5B7Y405
• Organism: Streptococcus sp. 1643
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 165514..175987

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD735_RS00945 (FD735_00945)	-	166252..167127 (-)	876	WP_139658273.1	RluA family pseudouridine synthase	-
FD735_RS00950 (FD735_00950)	pbp2a	167214..169409 (+)	2196	WP_139658274.1	penicillin-binding protein PBP2A	-
FD735_RS00955 (FD735_00955)	rpmG	169462..169614 (+)	153	WP_001809375.1	50S ribosomal protein L33	-
FD735_RS00960 (FD735_00960)	secE	169624..169800 (+)	177	WP_000505776.1	preprotein translocase subunit SecE	-
FD735_RS00965 (FD735_00965)	nusG	169858..170394 (+)	537	WP_000376728.1	transcription termination/antitermination protein NusG	-
FD735_RS00970 (FD735_00970)	comX/comX2	170514..170987 (+)	474	WP_049478144.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19273.09 Da
• Isoelectric Point: 7.8480

>NTDB_id=362621 FD735_RS00970 WP_049478144.1 170514..170987(+) (comX/comX2) [Streptococcus sp. 1643]
MNLKDLYEESKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSRNPELLEGERHQLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSVEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide

• Length: 474 bp

>NTDB_id=362621 FD735_RS00970 WP_049478144.1 170514..170987(+) (comX/comX2) [Streptococcus sp. 1643]
ATGAATCTAAAAGACTTATATGAAGAAAGTAAGGGAATTGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGACCAGGAAGGCATGTTATGTCTGTATGAGCTGGTGAGTCGCAACCCAGAGTTACTAGAGGGCGAGC
GCCATCAACTATATGTCTGCTTTAAAACAAAATTTAGAAATCGTATTCTAGATTACATCCGTAAACAGGAAAGTCACAAG
CGCCGTTTTGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGCCATCGTCTAGGAGAAAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAATTACAAATCAAAACAGAGTGTGGAAAAACAAGAATTAATAGACCGTCTCA
TGGGAGGGGAAGTCTTTAGAGGACGTAAAGCTCTCCTGAGAGAACTTTCCCTAATCTTTTCAGAATTTCGGTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A5B7Y405

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	64.286	98.089	0.631
comX/comX2	Streptococcus pneumoniae D39	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae D39	64.286	98.089	0.631
comX/comX2	Streptococcus pneumoniae R6	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae R6	64.286	98.089	0.631
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae Rx1	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae TIGR4	63.636	98.089	0.624
comX/comX2	Streptococcus pneumoniae TIGR4	63.636	98.089	0.624
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	62.987	98.089	0.618
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	62.987	98.089	0.618
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	62.987	98.089	0.618
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	53.205	99.363	0.529
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	53.205	99.363	0.529
comX/sigX	Streptococcus mutans UA159	46.711	96.815	0.452
comX/sigX	Streptococcus suis isolate S10	41.401	100	0.414
comX/sigX	Streptococcus suis D9	41.401	100	0.414
comX/sigX	Streptococcus suis P1/7	41.401	100	0.414
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.744	99.363	0.395
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.744	99.363	0.395
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	39.744	99.363	0.395
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	39.744	99.363	0.395
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	39.744	99.363	0.395
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	39.744	99.363	0.395
comX	Streptococcus sobrinus strain NIDR 6715-7	42.657	91.083	0.389
comX	Streptococcus thermophilus LMG 18311	40	95.541	0.382
comX	Streptococcus thermophilus LMD-9	40	95.541	0.382
comX	Streptococcus salivarius SK126	40	95.541	0.382
comX/sigX	Streptococcus salivarius strain HSISS4	40	95.541	0.382
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	37.342	100	0.376