Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ES276_RS09215 Genome accession   NZ_CP038252
Coordinates   1822122..1822811 (-) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1817122..1827811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS09195 (ES276_09780) - 1817717..1818592 (+) 876 WP_010963214.1 lanthionine synthetase LanC family protein -
  ES276_RS09200 (ES276_09785) - 1818635..1819867 (+) 1233 WP_000765691.1 MFS transporter -
  ES276_RS09205 (ES276_09790) cbpJ 1819985..1820983 (-) 999 WP_000698047.1 choline-binding protein CbpJ -
  ES276_RS09210 (ES276_09795) cbpC 1821001..1822023 (-) 1023 WP_000771084.1 choline-binding protein CbpC -
  ES276_RS09215 (ES276_09800) covR 1822122..1822811 (-) 690 WP_000518018.1 response regulator transcription factor Regulator
  ES276_RS09220 (ES276_09805) gndA 1822823..1824247 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  ES276_RS09225 (ES276_09810) mapZ 1824323..1825717 (-) 1395 WP_000039291.1 mid-cell-anchored protein MapZ -
  ES276_RS09230 (ES276_09815) - 1825730..1826887 (-) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  ES276_RS09240 (ES276_09825) gpsB 1827373..1827702 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=352646 ES276_RS09215 WP_000518018.1 1822122..1822811(-) (covR) [Streptococcus pneumoniae strain TVO_1901936]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=352646 ES276_RS09215 WP_000518018.1 1822122..1822811(-) (covR) [Streptococcus pneumoniae strain TVO_1901936]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment