Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   EHW89_RS07635 Genome accession   NZ_CP034543
Coordinates   1567685..1568158 (-) Length   157 a.a.
NCBI ID   WP_126467662.1    Uniprot ID   A0A3S9MT28
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1562685..1573158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS09685 - 1563868..1563997 (-) 130 Protein_1463 YSIRK-type signal peptide-containing protein -
  EHW89_RS07610 (EHW89_07610) - 1564254..1564658 (-) 405 WP_126467658.1 flavodoxin -
  EHW89_RS07615 (EHW89_07615) - 1564747..1564842 (-) 96 Protein_1465 NAD(P)H-dependent oxidoreductase -
  EHW89_RS07620 (EHW89_07620) - 1564839..1565435 (-) 597 WP_126467660.1 TetR/AcrR family transcriptional regulator -
  EHW89_RS09540 - 1565717..1566025 (-) 309 WP_226997571.1 hypothetical protein -
  EHW89_RS09545 - 1566022..1566588 (-) 567 WP_264371266.1 LacI family DNA-binding transcriptional regulator -
  EHW89_RS07630 (EHW89_07630) - 1566674..1567492 (-) 819 Protein_1469 Cof-type HAD-IIB family hydrolase -
  EHW89_RS07635 (EHW89_07635) comR/comR2 1567685..1568158 (-) 474 WP_126467662.1 sigma-70 family RNA polymerase sigma factor Regulator
  EHW89_RS07640 (EHW89_07640) nusB 1568376..1568801 (-) 426 WP_162614546.1 transcription antitermination factor NusB -
  EHW89_RS07645 (EHW89_07645) - 1568794..1569183 (-) 390 WP_006269324.1 Asp23/Gls24 family envelope stress response protein -
  EHW89_RS07650 (EHW89_07650) efp 1569294..1569854 (-) 561 WP_126467666.1 elongation factor P -
  EHW89_RS07655 (EHW89_07655) - 1569913..1570974 (-) 1062 WP_126467669.1 Xaa-Pro peptidase family protein -
  EHW89_RS07660 (EHW89_07660) - 1571122..1571877 (+) 756 WP_126467671.1 hypothetical protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19295.13 Da        Isoelectric Point: 7.2709

>NTDB_id=331799 EHW89_RS07635 WP_126467662.1 1567685..1568158(-) (comR/comR2) [Streptococcus periodonticum strain KCOM 2412]
MEFKELYGKVRGIVLKCRREYYVHLWELSDWEQEGMLVLYQLVSRYPQLVEEESQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=331799 EHW89_RS07635 WP_126467662.1 1567685..1568158(-) (comR/comR2) [Streptococcus periodonticum strain KCOM 2412]
ATGGAGTTCAAGGAGTTATATGGCAAGGTAAGAGGAATTGTGCTGAAGTGTCGGAGGGAATACTATGTTCACCTGTGGGA
GTTAAGCGATTGGGAACAAGAGGGCATGTTGGTGCTCTATCAGTTGGTGAGTCGCTATCCGCAGCTAGTAGAAGAAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGGAATCATATCCTGGACATCCTCCGTAAACAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGTTACCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTATGAGCGCTTACTAG
CTGACGAACGGTTCAAAGGCCGCCAAGCTATGATTCGAGAATTAAGAGCCTACTTAAAAGATTATAGTGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S9MT28

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae TIGR4

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae TIGR4

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae R6

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae D39

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae Rx1

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae Rx1

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae D39

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae R6

53.896

98.089

0.529
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

53.896

98.089

0.529
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

53.247

98.089

0.522
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

52.597

98.089

0.516
  comX/sigX Streptococcus mutans UA159

48.718

99.363

0.484
  comX/sigX Streptococcus suis isolate S10

48.387

98.726

0.478
  comX/sigX Streptococcus suis P1/7

48.387

98.726

0.478
  comX/sigX Streptococcus suis D9

48.387

98.726

0.478
  comX Streptococcus salivarius SK126

44.805

98.089

0.439
  comX/sigX Streptococcus salivarius strain HSISS4

44.156

98.089

0.433
  comX Streptococcus thermophilus LMG 18311

44.156

98.089

0.433
  comX Streptococcus thermophilus LMD-9

44.156

98.089

0.433
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.949

99.363

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.949

99.363

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.949

99.363

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.949

99.363

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.949

99.363

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.949

99.363

0.427
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.462

99.363

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

39.216

97.452

0.382

Multiple sequence alignment