Detailed information NTG0331388

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: EJF26_RS08550
• Genome accession: NZ_CP034442
• Coordinates: 1671069..1671542 (+)
• Length: 157 a.a.
• NCBI ID: WP_001049381.1
• Uniprot ID: A0A139M5Y8
• Organism: Streptococcus oralis subsp. dentisani strain F0392
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1666069..1676542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJF26_RS08525	-	1666808..1667683 (-)	876	WP_125845005.1	RluA family pseudouridine synthase	-
EJF26_RS08530	pbp2a	1667770..1669965 (+)	2196	WP_000762587.1	penicillin-binding protein PBP2A	-
EJF26_RS08535	rpmG	1670018..1670170 (+)	153	WP_001809375.1	50S ribosomal protein L33	-
EJF26_RS08540	secE	1670180..1670356 (+)	177	WP_000505776.1	preprotein translocase subunit SecE	-
EJF26_RS08545	nusG	1670413..1670949 (+)	537	WP_000376728.1	transcription termination/antitermination protein NusG	-
EJF26_RS08550	comX/comX2	1671069..1671542 (+)	474	WP_001049381.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19163.04 Da
• Isoelectric Point: 8.4595

>NTDB_id=331388 EJF26_RS08550 WP_001049381.1 1671069..1671542(+) (comX/comX2) [Streptococcus oralis subsp. dentisani strain F0392]
MNLKELYEESKGIVHKCRKEYHLHLWEKEDWDQEGMLCLYELVSHHPELLVGERRRLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKASQGKEKQEQLERLMGGECFKGRKALLGELRVVLSDFR

Nucleotide

• Length: 474 bp

>NTDB_id=331388 EJF26_RS08550 WP_001049381.1 1671069..1671542(+) (comX/comX2) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAATCTAAAAGAGTTGTATGAAGAAAGTAAAGGGATTGTCCATAAGTGCCGCAAAGAATACCATTTACATCTGTGGGA
GAAAGAGGACTGGGACCAGGAGGGGATGCTGTGCCTGTATGAGCTGGTCAGTCACCATCCAGAGTTACTAGTTGGTGAAC
GTCGCCGATTATATGTGTGCTTTAAAACCAAATTCCGCAATCGCATCCTAGACTACATCCGTAAACAGGAAAGTCACAAG
CGCCGTTTCGACAAAGAGCCTTATGAGGAGGTGAGTGAAATCAGCCATCGCCTAGGAGAAAAAGGACTGAGACTGGATGA
TTATTATCTCTTTCATGAGCTTCTAAAGAATTACAAGGCAAGTCAGGGGAAAGAAAAACAAGAACAACTAGAACGTCTGA
TGGGAGGAGAATGTTTCAAAGGACGCAAGGCACTTCTAGGAGAATTAAGAGTGGTATTGAGTGATTTTAGATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A139M5Y8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	66.234	98.089	0.65
comX/comX2	Streptococcus pneumoniae D39	66.234	98.089	0.65
comX/comX1	Streptococcus pneumoniae D39	66.234	98.089	0.65
comX/comX2	Streptococcus pneumoniae R6	66.234	98.089	0.65
comX/comX1	Streptococcus pneumoniae R6	66.234	98.089	0.65
comX/comX1	Streptococcus pneumoniae Rx1	66.234	98.089	0.65
comX/comX2	Streptococcus pneumoniae TIGR4	65.584	98.089	0.643
comX/comX1	Streptococcus pneumoniae TIGR4	65.584	98.089	0.643
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	64.286	98.089	0.631
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	64.286	98.089	0.631
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	63.636	98.089	0.624
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	62.987	98.089	0.618
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	53.846	99.363	0.535
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	53.846	99.363	0.535
comX/sigX	Streptococcus mutans UA159	48.026	96.815	0.465
comX/sigX	Streptococcus suis isolate S10	43.312	100	0.433
comX/sigX	Streptococcus suis D9	43.312	100	0.433
comX/sigX	Streptococcus suis P1/7	43.312	100	0.433
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.241	100	0.395
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	37.821	99.363	0.376
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	37.821	99.363	0.376
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	39.333	95.541	0.376
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	39.333	95.541	0.376
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	39.333	95.541	0.376
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	39.333	95.541	0.376
comX/sigX	Streptococcus salivarius strain HSISS4	39.333	95.541	0.376
comX	Streptococcus thermophilus LMG 18311	39.333	95.541	0.376
comX	Streptococcus thermophilus LMD-9	39.333	95.541	0.376
comX	Streptococcus salivarius SK126	39.333	95.541	0.376
comX	Streptococcus sobrinus strain NIDR 6715-7	40.559	91.083	0.369