Detailed information NTG0313500

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: D2E16_RS00075
• Genome accession: NZ_CP032064
• Coordinates: 16196..16666 (+)
• Length: 156 a.a.
• NCBI ID: WP_044683098.1
• Uniprot ID: A0A0Z8J070
• Organism: Streptococcus suis strain YSJ17
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 11196..21666

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D2E16_RS00060 (D2E16_00070)	tilS	12002..13270 (+)	1269	WP_171942912.1	tRNA lysidine(34) synthetase TilS	-
D2E16_RS00065 (D2E16_00075)	hpt	13278..13820 (+)	543	WP_014735203.1	hypoxanthine phosphoribosyltransferase	-
D2E16_RS00070 (D2E16_00080)	ftsH	13842..15815 (+)	1974	WP_192369416.1	ATP-dependent zinc metalloprotease FtsH	-
D2E16_RS00075 (D2E16_00085)	comX/sigX	16196..16666 (+)	471	WP_044683098.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 156 a.a.
• Molecular weight: 19131.01 Da
• Isoelectric Point: 8.4522

>NTDB_id=313500 D2E16_RS00075 WP_044683098.1 16196..16666(+) (comX/sigX) [Streptococcus suis strain YSJ17]
MEFEKVYASVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLEEQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKR
KFDRMPHEDIHELSHAIQSPGLINDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR

Nucleotide

• Length: 471 bp

>NTDB_id=313500 D2E16_RS00075 WP_044683098.1 16196..16666(+) (comX/sigX) [Streptococcus suis strain YSJ17]
ATGGAATTCGAAAAAGTGTACGCAAGCGTCAAAGGAATTGTAAACAAGGCTCGAAAAGAGTTTTACATTAAACTATGGGA
TCGAGATGATTGGGAACAAGAAGGAATGATGACCTTGTTTGAATTATTGGAAGAACAACCATGGTTAGTTGATGAGCAAG
TTCAATTATATTGCTATTTTAAAGTCAAGTTCAGAAATCGAATCAAAGATCGAATTCGTAAACAAGAAAGTCAAAAACGC
AAGTTTGATCGTATGCCACATGAAGATATTCATGAATTATCTCACGCCATACAATCACCGGGATTGATAAACGATGAACT
ATTAATGTTGAGAGGTGCCTTGAGAGATTATCGAAAAAATCTGAGTAATGATCAACTTGATAAATACGAAAAATTAATTA
GCGGACAATGTTTTAATGGTCGTCGTGAAATGATACGTGATTTACAAATTCATTTGAAAGACTTTCGCTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A0Z8J070

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus suis D9	99.359	100	0.994
comX/sigX	Streptococcus suis isolate S10	98.718	100	0.987
comX/sigX	Streptococcus suis P1/7	98.718	100	0.987
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	49.032	99.359	0.487
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	49.032	99.359	0.487
comX/comX1	Streptococcus pneumoniae TIGR4	46.358	96.795	0.449
comX/comX2	Streptococcus pneumoniae TIGR4	46.358	96.795	0.449
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	45.752	98.077	0.449
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	45.098	98.077	0.442
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	45.098	98.077	0.442
comX/comX2	Streptococcus pneumoniae R6	45.695	96.795	0.442
comX/comX2	Streptococcus pneumoniae D39	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae D39	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae Rx1	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae R6	45.695	96.795	0.442
comX/comX2	Streptococcus pneumoniae Rx1	45.695	96.795	0.442
comX/sigX	Streptococcus mutans UA159	43.871	99.359	0.436
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	44.444	98.077	0.436
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.645	99.359	0.404
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.645	99.359	0.404
comX	Streptococcus sobrinus strain NIDR 6715-7	40.523	98.077	0.397
comX	Streptococcus thermophilus LMD-9	40.523	98.077	0.397
comX	Streptococcus thermophilus LMG 18311	40.523	98.077	0.397
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	99.359	0.397
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	99.359	0.397
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	99.359	0.397
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	99.359	0.397
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.49	100	0.397
comX	Streptococcus salivarius SK126	39.869	98.077	0.391
comX/sigX	Streptococcus salivarius strain HSISS4	39.869	98.077	0.391