Detailed information NTG0030645

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: SDEG_RS01795
• Genome accession: NC_012891
• Coordinates: 341815..342297 (+)
• Length: 160 a.a.
• NCBI ID: WP_003057148.1
• Uniprot ID: A0A9X9GB62
• Organism: Streptococcus dysgalactiae subsp. equisimilis GGS_124
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 336815..347297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDEG_RS01795	comX/sigX/comX2/sigX2	341815..342297 (+)	483	WP_003057148.1	sigma-70 family RNA polymerase sigma factor	Regulator
SDEG_RS01800	-	342496..343425 (-)	930	Protein_311	IS30-like element IS1239 family transposase	-
SDEG_RS01805 (SDEG_0367)	-	343628..344155 (+)	528	WP_015057333.1	YqeG family HAD IIIA-type phosphatase	-
SDEG_RS01810 (SDEG_0368)	yqeH	344155..345273 (+)	1119	WP_012766583.1	ribosome biogenesis GTPase YqeH	-
SDEG_RS01815 (SDEG_0369)	yhbY	345299..345607 (+)	309	WP_003059820.1	ribosome assembly RNA-binding protein YhbY	-
SDEG_RS01820 (SDEG_0370)	-	345676..346308 (+)	633	WP_002991091.1	nicotinate-nucleotide adenylyltransferase	-
SDEG_RS01825 (SDEG_0371)	yqeK	346305..346898 (+)	594	WP_003061317.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
SDEG_RS01830 (SDEG_0372)	-	346874..347134 (+)	261	WP_011528257.1	isochorismatase family protein	-

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 18997.80 Da
• Isoelectric Point: 8.3220

>NTDB_id=30645 SDEG_RS01795 WP_003057148.1 341815..342297(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MSLETGEVFEKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVKLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQ
KRQFDKMAYEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSEADRKQFQALVRGERFKGRQALLRKVRPYFSGFDQG

Nucleotide

• Length: 483 bp

>NTDB_id=30645 SDEG_RS01795 WP_003057148.1 341815..342297(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
ATGTCGTTAGAGACAGGGGAGGTTTTTGAGAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACTTACAGTT
GTGGGAGACGGATGACTGGTTACAAGAGGGGCATTTGGTTTTAGTGAAGTTGTTGGAACGTCACCCAGAGTTAGTAGGAG
ATGAGGCTCGCTTGTATCGGTATTTTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAG
AAACGCCAGTTTGACAAGATGGCTTATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGCGGGTTATGGTTGGA
TGATTATGTGGCCTATCGGGAGGTTTTAGTACAAGTGGAGGAGGCCTTAAGCGAAGCGGATCGGAAGCAGTTTCAGGCCT
TAGTGAGAGGGGAACGGTTCAAGGGGCGTCAGGCTTTGCTTAGGAAGGTTCGTCCTTACTTTAGTGGGTTTGACCAAGGG
TGA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A9X9GB62

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	74.843	99.375	0.744
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	74.843	99.375	0.744
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	74.214	99.375	0.738
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	74.214	99.375	0.738
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	73.585	99.375	0.731
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	73.585	99.375	0.731
comX/sigX	Streptococcus mutans UA159	50	93.75	0.469
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.667	93.75	0.456
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	46.711	95	0.444
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	45.395	95	0.431
comX/comX1	Streptococcus pneumoniae Rx1	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae TIGR4	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae TIGR4	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae Rx1	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae D39	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae D39	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae R6	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae R6	45.033	94.375	0.425
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	44.079	95	0.419
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	44.079	95	0.419
comX	Streptococcus sobrinus strain NIDR 6715-7	44.079	95	0.419
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	44.079	95	0.419
comX	Streptococcus thermophilus LMG 18311	43.709	94.375	0.413
comX	Streptococcus thermophilus LMD-9	43.709	94.375	0.413
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	43.421	95	0.412
comX/sigX	Streptococcus salivarius strain HSISS4	41.722	94.375	0.394
comX	Streptococcus salivarius SK126	41.722	94.375	0.394
comX/sigX	Streptococcus suis D9	38.71	96.875	0.375
comX/sigX	Streptococcus suis isolate S10	38.71	96.875	0.375
comX/sigX	Streptococcus suis P1/7	38.71	96.875	0.375