Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   SPH_RS10805 Genome accession   NC_010380
Coordinates   2025114..2025437 (-) Length   107 a.a.
NCBI ID   WP_000738648.1    Uniprot ID   -
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2020114..2030437
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS10760 (SPH_2195) rnpA 2020131..2020502 (-) 372 WP_000739244.1 ribonuclease P protein component -
  SPH_RS14265 (SPH_2196) - 2020519..2020650 (-) 132 WP_000768904.1 hypothetical protein -
  SPH_RS10765 (SPH_2197) - 2020651..2021841 (-) 1191 WP_000167753.1 acetate kinase -
  SPH_RS10770 (SPH_2198) comYH 2021892..2022845 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  SPH_RS12980 - 2022906..2023500 (-) 595 Protein_2032 methyltransferase domain-containing protein -
  SPH_RS10785 (SPH_2201) comGG/cglG 2023637..2024050 (-) 414 WP_000265625.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPH_RS10790 (SPH_2202) comGF/cglF 2024028..2024489 (-) 462 WP_000250508.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPH_RS10795 (SPH_2203) comGE/cglE 2024452..2024754 (-) 303 WP_191995726.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPH_RS10800 (SPH_2204) comGD/cglD 2024717..2025151 (-) 435 WP_041864711.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPH_RS10805 (SPH_2205) comGC/cglC 2025114..2025437 (-) 324 WP_000738648.1 comG operon protein ComGC Machinery gene
  SPH_RS10810 (SPH_2206) comGB/cglB 2025439..2026455 (-) 1017 WP_079218398.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPH_RS10815 (SPH_2207) comGA/cglA/cilD 2026403..2027344 (-) 942 WP_000249559.1 competence type IV pilus ATPase ComGA Machinery gene
  SPH_RS10820 (SPH_2208) - 2027420..2027785 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPH_RS10825 (SPH_2209) - 2028052..2029307 (+) 1256 WP_088804233.1 ISL3 family transposase -
  SPH_RS10830 (SPH_2210) - 2029356..2030414 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 11982.20 Da        Isoelectric Point: 10.1889

>NTDB_id=30046 SPH_RS10805 WP_000738648.1 2025114..2025437(-) (comGC/cglC) [Streptococcus pneumoniae Hungary19A-6]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLGKNEEASLNKLQA
DGRITEEQAKAYKEYHAKQNKTQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=30046 SPH_RS10805 WP_000738648.1 2025114..2025437(-) (comGC/cglC) [Streptococcus pneumoniae Hungary19A-6]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTCACTCTGGTAGAGATGTTAGTGGTCCTTTTAAT
CATCAGTGTGCTTCTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTAGAAAGCCAGGCAGAGCTTTATAGTTTGGGAAAAAATGAAGAGGCTAGCCTAAACAAGTTACAAGCA
GATGGGCGAATCACCGAGGAACAGGCTAAAGCCTATAAAGAATACCATGCTAAACAAAATAAGACTCAAACGGTCGCAGA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

95.327

100

0.953
  comGC/cglC Streptococcus mitis SK321

94.898

91.589

0.869
  comGC/cglC Streptococcus pneumoniae D39

94.898

91.589

0.869
  comGC/cglC Streptococcus pneumoniae R6

94.898

91.589

0.869
  comGC/cglC Streptococcus pneumoniae Rx1

94.898

91.589

0.869
  comGC/cglC Streptococcus pneumoniae TIGR4

93.878

91.589

0.86
  comYC Streptococcus gordonii str. Challis substr. CH1

68.571

98.131

0.673
  comYC Streptococcus mutans UA140

65.385

97.196

0.636
  comYC Streptococcus mutans UA159

65.385

97.196

0.636
  comYC Streptococcus suis isolate S10

71.605

75.701

0.542
  comGC Lactococcus lactis subsp. cremoris KW2

55.67

90.654

0.505
  comGC Staphylococcus aureus MW2

51.163

80.374

0.411
  comGC Staphylococcus aureus N315

51.163

80.374

0.411
  comGC Latilactobacillus sakei subsp. sakei 23K

44.828

81.308

0.364

Multiple sequence alignment