Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   SPH_RS10785 Genome accession   NC_010380
Coordinates   2023637..2024050 (-) Length   137 a.a.
NCBI ID   WP_000265625.1    Uniprot ID   -
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2018637..2029050
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS10755 (SPH_2194) - 2019332..2020156 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  SPH_RS10760 (SPH_2195) rnpA 2020131..2020502 (-) 372 WP_000739244.1 ribonuclease P protein component -
  SPH_RS14265 (SPH_2196) - 2020519..2020650 (-) 132 WP_000768904.1 hypothetical protein -
  SPH_RS10765 (SPH_2197) - 2020651..2021841 (-) 1191 WP_000167753.1 acetate kinase -
  SPH_RS10770 (SPH_2198) comYH 2021892..2022845 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  SPH_RS12980 - 2022906..2023500 (-) 595 Protein_2032 methyltransferase domain-containing protein -
  SPH_RS10785 (SPH_2201) comGG/cglG 2023637..2024050 (-) 414 WP_000265625.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPH_RS10790 (SPH_2202) comGF/cglF 2024028..2024489 (-) 462 WP_000250508.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPH_RS10795 (SPH_2203) comGE/cglE 2024452..2024754 (-) 303 WP_191995726.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPH_RS10800 (SPH_2204) comGD/cglD 2024717..2025151 (-) 435 WP_041864711.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPH_RS10805 (SPH_2205) comGC/cglC 2025114..2025437 (-) 324 WP_000738648.1 comG operon protein ComGC Machinery gene
  SPH_RS10810 (SPH_2206) comGB/cglB 2025439..2026455 (-) 1017 WP_079218398.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPH_RS10815 (SPH_2207) comGA/cglA/cilD 2026403..2027344 (-) 942 WP_000249559.1 competence type IV pilus ATPase ComGA Machinery gene
  SPH_RS10820 (SPH_2208) - 2027420..2027785 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence


Protein


Download         Length: 137 a.a.        Molecular weight: 15931.42 Da        Isoelectric Point: 10.3657

>NTDB_id=30042 SPH_RS10785 WP_000265625.1 2023637..2024050(-) (comGG/cglG) [Streptococcus pneumoniae Hungary19A-6]
MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHHRDYALNKEKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKK
TNLVTTVRTPKSQYEFIFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide


Download         Length: 414 bp        

>NTDB_id=30042 SPH_RS10785 WP_000265625.1 2023637..2024050(-) (comGG/cglG) [Streptococcus pneumoniae Hungary19A-6]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTATATGCAGTCACCATGGCAGCTATCTTTAGTCTTTTGTTACA
ATTTTACTTGAACCGACAAGTAGCCCACCATAGAGACTATGCTTTAAATAAAGAAAAGTTGGTTGCTTTTGCTATGGCCA
AACGAACCAAGGATAAAGCTGAGCAAGAAAGTGGGGAACAGGTTTTTAATCTAGGTCAGGTAAGCTATCAAAATAAGAAA
ACAAACTTGGTGACGACGGTTCGTACGCCTAAGAGCCAATATGAATTTATCTTTCCTTCCGTCAAAATTAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCCTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus mitis SK321

85.401

100

0.854

  comGG/cglG Streptococcus mitis NCTC 12261

90.083

88.321

0.796

  comGG/cglG Streptococcus pneumoniae D39

92.308

85.401

0.788

  comGG/cglG Streptococcus pneumoniae TIGR4

92.308

85.401

0.788

  comGG/cglG Streptococcus pneumoniae R6

92.308

85.401

0.788

  comGG/cglG Streptococcus pneumoniae Rx1

92.308

85.401

0.788

  comYG Streptococcus mutans UA140

40.299

97.81

0.394

  comYG Streptococcus mutans UA159

40.299

97.81

0.394


Multiple sequence alignment