Detailed information NTG0030043

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: SPH_RS10790
• Genome accession: NC_010380
• Coordinates: 2024028..2024489 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250508.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae Hungary19A-6
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2019028..2029489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPH_RS10755 (SPH_2194)	-	2019332..2020156 (-)	825	WP_001832473.1	membrane protein insertase YidC	-
SPH_RS10760 (SPH_2195)	rnpA	2020131..2020502 (-)	372	WP_000739244.1	ribonuclease P protein component	-
SPH_RS14265 (SPH_2196)	-	2020519..2020650 (-)	132	WP_000768904.1	hypothetical protein	-
SPH_RS10765 (SPH_2197)	-	2020651..2021841 (-)	1191	WP_000167753.1	acetate kinase	-
SPH_RS10770 (SPH_2198)	comYH	2021892..2022845 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
SPH_RS12980	-	2022906..2023500 (-)	595	Protein_2032	methyltransferase domain-containing protein	-
SPH_RS10785 (SPH_2201)	comGG/cglG	2023637..2024050 (-)	414	WP_000265625.1	competence type IV pilus minor pilin ComGG	Machinery gene
SPH_RS10790 (SPH_2202)	comGF/cglF	2024028..2024489 (-)	462	WP_000250508.1	competence type IV pilus minor pilin ComGF	Machinery gene
SPH_RS10795 (SPH_2203)	comGE/cglE	2024452..2024754 (-)	303	WP_191995726.1	competence type IV pilus minor pilin ComGE	Machinery gene
SPH_RS10800 (SPH_2204)	comGD/cglD	2024717..2025151 (-)	435	WP_041864711.1	competence type IV pilus minor pilin ComGD	Machinery gene
SPH_RS10805 (SPH_2205)	comGC/cglC	2025114..2025437 (-)	324	WP_000738648.1	comG operon protein ComGC	Machinery gene
SPH_RS10810 (SPH_2206)	comGB/cglB	2025439..2026455 (-)	1017	WP_079218398.1	competence type IV pilus assembly protein ComGB	Machinery gene
SPH_RS10815 (SPH_2207)	comGA/cglA/cilD	2026403..2027344 (-)	942	WP_000249559.1	competence type IV pilus ATPase ComGA	Machinery gene
SPH_RS10820 (SPH_2208)	-	2027420..2027785 (-)	366	WP_000286415.1	DUF1033 family protein	-
SPH_RS10825 (SPH_2209)	-	2028052..2029307 (+)	1256	WP_088804233.1	ISL3 family transposase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.53 Da
• Isoelectric Point: 8.8053

>NTDB_id=30043 SPH_RS10790 WP_000250508.1 2024028..2024489(-) (comGF/cglF) [Streptococcus pneumoniae Hungary19A-6]
MVQNSCWLLKSHKVKAFTLLESLIALIVISGGLLLFQAMSQLLVSEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKEIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=30043 SPH_RS10790 WP_000250508.1 2024028..2024489(-) (comGF/cglF) [Streptococcus pneumoniae Hungary19A-6]
ATGGTTCAGAACAGTTGTTGGCTATTAAAGAGCCATAAGGTCAAGGCTTTTACCTTATTAGAATCCCTGATTGCCCTCAT
TGTCATCAGTGGAGGCTTACTCCTATTTCAGGCCATGAGTCAGCTCCTCGTTTCAGAAGTTCGCTACCAGCAACAGAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAGTTGGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTCTATATGAAGCAGGATGGCAAGGAAATTGCGATAGGCAAGTCTAAATCAGATGATTTTCGGAAAACCGATGCCAG
TGGACGAGGTTATCAGCCTATGGTTTATGGACTCAAATCCGCACAGATTACAGAGGACAATCAACTGGTTCGTTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (46-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae Rx1	92.81	100	0.928
comGF/cglF	Streptococcus pneumoniae D39	92.81	100	0.928
comGF/cglF	Streptococcus pneumoniae R6	92.81	100	0.928
comGF/cglF	Streptococcus pneumoniae TIGR4	92.81	100	0.928
comYF	Streptococcus mutans UA159	40.288	90.85	0.366
comYF	Streptococcus mutans UA140	40.288	90.85	0.366