Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   DG474_RS00945 Genome accession   NZ_CP029257
Coordinates   180982..181455 (+) Length   157 a.a.
NCBI ID   WP_255778330.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 175982..186455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS00920 (DG474_00925) - 176719..177594 (-) 876 WP_255778326.1 RluA family pseudouridine synthase -
  DG474_RS00925 (DG474_00930) pbp2a 177681..179876 (+) 2196 WP_049478889.1 penicillin-binding protein PBP2A -
  DG474_RS00930 (DG474_00935) rpmG 179929..180081 (+) 153 WP_001809375.1 50S ribosomal protein L33 -
  DG474_RS00935 (DG474_00940) secE 180091..180267 (+) 177 WP_000505776.1 preprotein translocase subunit SecE -
  DG474_RS00940 (DG474_00945) nusG 180325..180861 (+) 537 WP_000376728.1 transcription termination/antitermination protein NusG -
  DG474_RS00945 (DG474_00950) comX/comX2 180982..181455 (+) 474 WP_255778330.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19359.29 Da        Isoelectric Point: 8.2593

>NTDB_id=291396 DG474_RS00945 WP_255778330.1 180982..181455(+) (comX/comX2) [Streptococcus oralis strain CCUG 53468]
MNLKDLYEEIKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSRNPELLEGERHRLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSMEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=291396 DG474_RS00945 WP_255778330.1 180982..181455(+) (comX/comX2) [Streptococcus oralis strain CCUG 53468]
ATGAATCTAAAAGACTTATATGAAGAAATTAAGGGAATCGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGATCAGGAAGGCATGTTATGTCTGTATGAGCTGGTGAGTCGCAATCCAGAGTTACTAGAGGGCGAGC
GCCATCGACTTTATGTCTGCTTTAAAACAAAGTTTAGAAATCGTATCCTAGATTACATCCGTAAACAGGAAAGCCACAAA
CGCCGTTTTGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGCCATCGTCTAGGAGAAAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAATTACAAATCAAAACAGAGTATGGAAAAACAAGAATTAATAGACCGTCTCA
TGGGAGGGGAAGTCTTTAGAGGACGGAAAGCTCTCCTGAGAGAACTTTCCCTAATCTTTTCAGAATTTCGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

63.636

98.089

0.624
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

63.636

98.089

0.624
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

63.636

98.089

0.624
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comX/sigX Streptococcus mutans UA159

46.711

96.815

0.452
  comX/sigX Streptococcus suis D9

40.764

100

0.408
  comX/sigX Streptococcus suis isolate S10

40.764

100

0.408
  comX/sigX Streptococcus suis P1/7

40.764

100

0.408
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40.385

99.363

0.401
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40.385

99.363

0.401
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40.385

99.363

0.401
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40.385

99.363

0.401
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40.385

99.363

0.401
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40.385

99.363

0.401
  comX Streptococcus sobrinus strain NIDR 6715-7

40.667

95.541

0.389
  comX Streptococcus thermophilus LMG 18311

40

95.541

0.382
  comX Streptococcus thermophilus LMD-9

40

95.541

0.382
  comX Streptococcus salivarius SK126

40

95.541

0.382
  comX/sigX Streptococcus salivarius strain HSISS4

40

95.541

0.382
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.342

100

0.376

Multiple sequence alignment