Detailed information NTG0027493

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: SSA_RS00080
• Genome accession: NC_009009
• Coordinates: 15627..16112 (+)
• Length: 161 a.a.
• NCBI ID: WP_011836282.1
• Uniprot ID: A3CJY0
• Organism: Streptococcus sanguinis SK36
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 10627..21112

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSA_RS00055 (SSA_0013)	tilS	11336..12613 (+)	1278	WP_011836281.1	tRNA lysidine(34) synthetase TilS	-
SSA_RS00060 (SSA_0014)	hpt	12618..13160 (+)	543	WP_032913750.1	hypoxanthine phosphoribosyltransferase	-
SSA_RS00065 (SSA_0015)	ftsH	13178..15157 (+)	1980	WP_002894312.1	ATP-dependent zinc metalloprotease FtsH	-
SSA_RS00080 (SSA_0016)	comR/comR2	15627..16112 (+)	486	WP_011836282.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 20094.02 Da
• Isoelectric Point: 9.3624

>NTDB_id=27493 SSA_RS00080 WP_011836282.1 15627..16112(+) (comR/comR2) [Streptococcus sanguinis SK36]
MDFRTTYEKVKWIVWKCKKDYYIHLWEHSDWEQEGMLVLYELLLKEKRIENDEEKLYRYFKTKFRNHIHDKIRKQESQKR
KLDRQPYEEVSEIGHRLKSKELFLDELVAFREAIDNYKRTLDDVGLDNYQRLMSNERFKGRRAMLKDLKNHLKDFQDNTI
L

Nucleotide

• Length: 486 bp

>NTDB_id=27493 SSA_RS00080 WP_011836282.1 15627..16112(+) (comR/comR2) [Streptococcus sanguinis SK36]
ATGGATTTTAGAACTACTTATGAGAAGGTGAAATGGATAGTTTGGAAGTGTAAGAAAGACTATTATATTCATTTGTGGGA
ACATAGTGATTGGGAGCAAGAAGGAATGTTGGTTTTATACGAACTTCTGCTTAAAGAAAAAAGAATTGAAAACGATGAGG
AAAAACTCTATCGTTATTTCAAAACAAAATTCAGAAATCATATACATGATAAAATTCGTAAACAAGAAAGCCAAAAGCGA
AAATTGGACCGCCAGCCTTATGAAGAAGTGAGTGAGATTGGACATCGTTTGAAATCAAAAGAATTGTTTCTGGATGAGTT
AGTTGCCTTCAGAGAAGCGATTGACAATTATAAAAGAACTCTTGATGATGTTGGATTGGATAATTATCAGAGGTTGATGA
GCAACGAGCGCTTTAAAGGAAGAAGAGCCATGCTTAAAGATTTAAAAAATCACTTAAAAGATTTTCAAGATAATACGATT
TTGTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A3CJY0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comX/sigX	Streptococcus suis D9	49.359	96.894	0.478
comX/sigX	Streptococcus suis isolate S10	49.359	96.894	0.478
comX/sigX	Streptococcus suis P1/7	49.359	96.894	0.478
comX/comX2	Streptococcus pneumoniae TIGR4	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae TIGR4	49.673	95.031	0.472
comX/comX2	Streptococcus pneumoniae Rx1	49.02	95.031	0.466
comX/comX1	Streptococcus pneumoniae Rx1	49.02	95.031	0.466
comX/comX2	Streptococcus pneumoniae D39	49.02	95.031	0.466
comX/comX1	Streptococcus pneumoniae D39	49.02	95.031	0.466
comX/comX2	Streptococcus pneumoniae R6	49.02	95.031	0.466
comX/comX1	Streptococcus pneumoniae R6	49.02	95.031	0.466
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	47.134	97.516	0.46
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	47.134	97.516	0.46
comX/sigX	Streptococcus mutans UA159	47.436	96.894	0.46
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	46.497	97.516	0.453
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	45.223	97.516	0.441
comX	Streptococcus sobrinus strain NIDR 6715-7	41.212	100	0.422
comX	Streptococcus thermophilus LMD-9	42.949	96.894	0.416
comX	Streptococcus thermophilus LMG 18311	42.949	96.894	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.405	98.137	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.405	98.137	0.416
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.405	98.137	0.416
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.405	98.137	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.772	98.137	0.41
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.772	98.137	0.41
comX/sigX	Streptococcus salivarius strain HSISS4	41.176	95.031	0.391
comX	Streptococcus salivarius SK126	41.176	95.031	0.391
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.49	97.516	0.385