Detailed information NTG0195371

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: A7J08_RS00080
• Genome accession: NZ_CP017088
• Coordinates: 16438..16908 (+)
• Length: 156 a.a.
• NCBI ID: WP_053867433.1
• Uniprot ID: A0A4T2GRD9
• Organism: Streptococcus suis strain SRD478
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	17507..18670	16438..16908	flank	599

Gene organization within MGE regions

Location: 16438..18670

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J08_RS00080 (A7J08_00080)	comX/sigX	16438..16908 (+)	471	WP_053867433.1	sigma-70 family RNA polymerase sigma factor	Regulator
A7J08_RS00085 (A7J08_00085)	-	17507..18670 (-)	1164	WP_053867435.1	IS30 family transposase	-

Sequence

Protein

• Length: 156 a.a.
• Molecular weight: 19102.96 Da
• Isoelectric Point: 8.4522

>NTDB_id=195371 A7J08_RS00080 WP_053867433.1 16438..16908(+) (comX/sigX) [Streptococcus suis strain SRD478]
MDFEKVYASVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLEDQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKR
KFDRMPHEDIHELSHAIQSPGLINDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR

Nucleotide

• Length: 471 bp

>NTDB_id=195371 A7J08_RS00080 WP_053867433.1 16438..16908(+) (comX/sigX) [Streptococcus suis strain SRD478]
ATGGACTTCGAAAAAGTGTATGCAAGCGTCAAAGGTATTGTAAACAAGGCTCGAAAAGAGTTTTACATTAAACTATGGGA
TCGAGATGATTGGGAACAAGAAGGAATGATGACCTTGTTTGAATTGTTGGAAGATCAACCGTGGCTAGTTGATGAACAAG
TTCAATTATATTGTTATTTCAAAGTCAAGTTCAGAAATCGAATCAAGGATCGTATCCGCAAACAGGAAAGTCAAAAACGC
AAGTTTGACCGTATGCCACATGAAGATATTCACGAATTATCTCACGCAATACAATCACCGGGATTGATAAACGATGAACT
ATTAATGTTGAGAGGTGCCTTGAGAGATTATCGAAAAAATCTGAGCAATGATCAACTTGATAAATACGAAAAATTAATTA
GCGGACAATGTTTTAATGGTCGTCGTGAAATGATACGTGATTTACAAATTCATTTGAAAGACTTTCGCTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A4T2GRD9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus suis D9	98.718	100	0.987
comX/sigX	Streptococcus suis isolate S10	98.077	100	0.981
comX/sigX	Streptococcus suis P1/7	98.077	100	0.981
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	49.032	99.359	0.487
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	49.032	99.359	0.487
comX/comX2	Streptococcus pneumoniae TIGR4	46.358	96.795	0.449
comX/comX1	Streptococcus pneumoniae TIGR4	46.358	96.795	0.449
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	45.752	98.077	0.449
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	45.098	98.077	0.442
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	45.098	98.077	0.442
comX/comX2	Streptococcus pneumoniae R6	45.695	96.795	0.442
comX/comX2	Streptococcus pneumoniae D39	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae D39	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae Rx1	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae R6	45.695	96.795	0.442
comX/comX2	Streptococcus pneumoniae Rx1	45.695	96.795	0.442
comX/sigX	Streptococcus mutans UA159	43.871	99.359	0.436
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	44.444	98.077	0.436
comX	Streptococcus thermophilus LMG 18311	40.523	98.077	0.397
comX	Streptococcus sobrinus strain NIDR 6715-7	40.523	98.077	0.397
comX	Streptococcus thermophilus LMD-9	40.523	98.077	0.397
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.333	96.154	0.397
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.333	96.154	0.397
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.49	100	0.397
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40.667	96.154	0.391
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40.667	96.154	0.391
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40.667	96.154	0.391
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40.667	96.154	0.391
comX/sigX	Streptococcus salivarius strain HSISS4	39.869	98.077	0.391
comX	Streptococcus salivarius SK126	39.869	98.077	0.391