Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   A0O21_RS07940 Genome accession   NZ_CP014699
Coordinates   1707152..1707631 (-) Length   159 a.a.
NCBI ID   WP_067064004.1    Uniprot ID   A0A172Q8X9
Organism   Streptococcus pantholopis strain TA 26     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1702152..1712631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS07910 (A0O21_07910) - 1702464..1703048 (-) 585 Protein_1557 M15 family metallopeptidase -
  A0O21_RS07915 (A0O21_07915) - 1703204..1703908 (-) 705 WP_067063994.1 histidine phosphatase family protein -
  A0O21_RS07920 (A0O21_07920) - 1703984..1705321 (-) 1338 WP_067063996.1 PFL family protein -
  A0O21_RS07925 (A0O21_07925) - 1705340..1705606 (-) 267 WP_067063999.1 ACT domain-containing protein -
  A0O21_RS07930 (A0O21_07930) - 1705815..1706050 (-) 236 Protein_1561 GlsB/YeaQ/YmgE family stress response membrane protein -
  A0O21_RS07935 (A0O21_07935) - 1706177..1706863 (+) 687 WP_067064002.1 XRE family transcriptional regulator -
  A0O21_RS07940 (A0O21_07940) comX/sigX/comX2/sigX2 1707152..1707631 (-) 480 WP_067064004.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19497.47 Da        Isoelectric Point: 8.4063

>NTDB_id=173370 A0O21_RS07940 WP_067064004.1 1707152..1707631(-) (comX/sigX/comX2/sigX2) [Streptococcus pantholopis strain TA 26]
MREEEFDELYKKVRPIILKLKRSYHIHLWDYNDWLQEGSIVLFRLLDAHPDLCQDELRLYVYFKTKFSNYLKDVIRQQES
YKRKFNKMAYEDISQLSHCISDNALSLDDYVAYRELVQDIEKNLEGQEREMFQKLLQGERFAGRRKMIKKLQPLFKDFK

Nucleotide


Download         Length: 480 bp        

>NTDB_id=173370 A0O21_RS07940 WP_067064004.1 1707152..1707631(-) (comX/sigX/comX2/sigX2) [Streptococcus pantholopis strain TA 26]
ATGCGAGAAGAAGAGTTTGATGAGCTATATAAAAAAGTTAGGCCGATTATTTTAAAGTTAAAACGCAGTTATCATATTCA
CCTGTGGGACTATAATGACTGGCTGCAGGAAGGCAGCATTGTCTTGTTCAGGCTTTTGGATGCGCATCCTGACTTGTGTC
AGGATGAATTGCGCTTGTACGTCTACTTTAAGACTAAATTTTCTAATTATTTAAAAGATGTTATTCGTCAGCAAGAAAGC
TACAAGCGAAAATTTAATAAAATGGCTTATGAAGACATTAGCCAGCTCAGTCACTGTATCAGTGATAATGCCTTATCTTT
AGATGACTATGTTGCTTATAGAGAGCTTGTTCAAGATATCGAAAAGAATTTAGAGGGGCAGGAGCGCGAGATGTTTCAAA
AACTTTTGCAAGGGGAGCGTTTTGCAGGACGTCGAAAAATGATAAAAAAACTTCAGCCTTTGTTTAAAGATTTTAAGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q8X9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

55.844

96.855

0.541
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

55.844

96.855

0.541
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

57.047

93.711

0.535
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

57.047

93.711

0.535
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

56.376

93.711

0.528
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

56.376

93.711

0.528
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.077

98.113

0.472
  comX/sigX Streptococcus mutans UA159

45.86

98.742

0.453
  comX/sigX Streptococcus suis D9

45.161

97.484

0.44
  comX/sigX Streptococcus suis isolate S10

45.161

97.484

0.44
  comX/sigX Streptococcus suis P1/7

45.161

97.484

0.44
  comX Streptococcus thermophilus LMD-9

43.038

99.371

0.428
  comX Streptococcus thermophilus LMG 18311

43.038

99.371

0.428
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

42.484

96.226

0.409
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

42.484

96.226

0.409
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

41.83

96.226

0.403
  comX/sigX Streptococcus salivarius strain HSISS4

40.506

99.371

0.403
  comX Streptococcus salivarius SK126

40.506

99.371

0.403
  comX Streptococcus sobrinus strain NIDR 6715-7

39.873

99.371

0.396
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

40.523

96.226

0.39
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

39.869

96.226

0.384
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

39.869

96.226

0.384
  comX/comX1 Streptococcus pneumoniae Rx1

39.735

94.969

0.377
  comX/comX2 Streptococcus pneumoniae D39

39.735

94.969

0.377
  comX/comX1 Streptococcus pneumoniae D39

39.735

94.969

0.377
  comX/comX2 Streptococcus pneumoniae R6

39.735

94.969

0.377
  comX/comX1 Streptococcus pneumoniae R6

39.735

94.969

0.377
  comX/comX1 Streptococcus pneumoniae TIGR4

39.735

94.969

0.377
  comX/comX2 Streptococcus pneumoniae TIGR4

39.735

94.969

0.377
  comX/comX2 Streptococcus pneumoniae Rx1

39.735

94.969

0.377

Multiple sequence alignment