Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   AXE83_RS08595 Genome accession   NZ_CP014264
Coordinates   1817711..1818175 (-) Length   154 a.a.
NCBI ID   WP_060956137.1    Uniprot ID   A0A0X8JZ96
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1812711..1823175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS08595 (AXE83_08595) comX/sigX/comX2/sigX2 1817711..1818175 (-) 465 WP_060956137.1 sigma-70 family RNA polymerase sigma factor Regulator
  AXE83_RS08600 (AXE83_08600) nusG 1818379..1818915 (-) 537 WP_045763385.1 transcription termination/antitermination protein NusG -
  AXE83_RS08605 (AXE83_08605) secE 1818973..1819149 (-) 177 WP_001211016.1 preprotein translocase subunit SecE -
  AXE83_RS08610 (AXE83_08610) rpmG 1819159..1819311 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  AXE83_RS08615 (AXE83_08615) - 1819543..1820235 (-) 693 WP_000240128.1 phosphoglycerate mutase -
  AXE83_RS08620 (AXE83_08620) - 1820372..1820740 (-) 369 WP_060956138.1 hypothetical protein -
  AXE83_RS08625 (AXE83_08625) - 1821215..1822513 (+) 1299 WP_083280559.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 19084.88 Da        Isoelectric Point: 7.4283

>NTDB_id=170016 AXE83_RS08595 WP_060956137.1 1817711..1818175(-) (comX/sigX/comX2/sigX2) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MLEKYYAKVKGIVHKCRKDYYLHLWEKEDWDQEGMICLHELLEKHPELVEEEKKLYVYFKTKFRNRILDSVRKQESQKRR
LDRMAYEEVGEISHRLPEGGLWLDDYYALHELLNTYRRKLPEDKQEAYERLWADERFKGRKALLRELKETLQDF

Nucleotide


Download         Length: 465 bp        

>NTDB_id=170016 AXE83_RS08595 WP_060956137.1 1817711..1818175(-) (comX/sigX/comX2/sigX2) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGCTTGAGAAGTATTATGCAAAGGTAAAAGGAATTGTTCATAAATGTAGAAAAGACTACTATCTCCACCTGTGGGAGAA
AGAGGATTGGGACCAAGAAGGCATGATCTGTCTCCATGAACTTCTAGAAAAGCATCCAGAACTAGTGGAAGAGGAAAAGA
AACTCTACGTCTACTTCAAAACAAAATTTCGCAATCGAATCCTTGATAGCGTCAGAAAACAAGAGAGTCAAAAGCGTCGC
CTAGACCGAATGGCCTATGAAGAAGTAGGAGAGATTAGCCATCGCCTACCAGAAGGAGGATTGTGGTTGGATGATTACTA
CGCCCTTCATGAATTGTTGAATACTTATAGAAGAAAGTTACCAGAAGATAAACAAGAAGCCTACGAACGACTCTGGGCAG
ACGAACGATTTAAAGGCCGCAAAGCCCTTCTAAGAGAACTGAAGGAAACATTACAAGACTTCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JZ96

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

62.987

100

0.63
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

61.688

100

0.617
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

61.688

100

0.617
  comX/comX2 Streptococcus pneumoniae D39

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae D39

59.74

100

0.597
  comX/comX2 Streptococcus pneumoniae R6

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae R6

59.74

100

0.597
  comX/comX2 Streptococcus pneumoniae Rx1

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae Rx1

59.74

100

0.597
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae TIGR4

59.091

100

0.591
  comX/comX2 Streptococcus pneumoniae TIGR4

59.091

100

0.591
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

57.516

99.351

0.571
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

57.516

99.351

0.571
  comX/sigX Streptococcus mutans UA159

51.634

99.351

0.513
  comX/sigX Streptococcus suis D9

50.327

99.351

0.5
  comX/sigX Streptococcus suis isolate S10

50.327

99.351

0.5
  comX/sigX Streptococcus suis P1/7

50.327

99.351

0.5
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

47.651

96.753

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

47.651

96.753

0.461
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

47.651

96.753

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

47.651

96.753

0.461
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

47.651

96.753

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

47.651

96.753

0.461
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

42.857

100

0.429
  comX/sigX Streptococcus salivarius strain HSISS4

44.295

96.753

0.429
  comX Streptococcus salivarius SK126

44.295

96.753

0.429
  comX Streptococcus sobrinus strain NIDR 6715-7

44.295

96.753

0.429
  comX Streptococcus thermophilus LMG 18311

42.384

98.052

0.416
  comX Streptococcus thermophilus LMD-9

42.384

98.052

0.416

Multiple sequence alignment