Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   AV644_RS00720 Genome accession   NZ_CP013908
Coordinates   100616..101095 (+) Length   159 a.a.
NCBI ID   WP_001204194.1    Uniprot ID   A0AAV3JNR5
Organism   Streptococcus agalactiae strain GBS-M002     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 95616..106095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AV644_RS00695 (AV644_00685) - 97644..97901 (+) 258 WP_075316585.1 hypothetical protein -
  AV644_RS00700 - 97901..98071 (+) 171 WP_000388348.1 hypothetical protein -
  AV644_RS00705 - 98141..98311 (+) 171 WP_000840973.1 hypothetical protein -
  AV644_RS00710 (AV644_00690) - 99226..99777 (+) 552 WP_000161851.1 nucleotidyltransferase family protein -
  AV644_RS00715 (AV644_00695) - 99997..100416 (+) 420 WP_000784700.1 YjdF family protein -
  AV644_RS00720 (AV644_00700) comX/sigX 100616..101095 (+) 480 WP_001204194.1 sigma-70 family RNA polymerase sigma factor Regulator
  AV644_RS00725 (AV644_00705) - 101217..101909 (+) 693 WP_000049272.1 histidine phosphatase family protein -
  AV644_RS00730 (AV644_00710) - 101906..102658 (+) 753 WP_000739660.1 M15 family metallopeptidase -
  AV644_RS00735 (AV644_00715) - 102655..103230 (+) 576 WP_001231504.1 glycoside hydrolase family 73 protein -
  AV644_RS00740 (AV644_00720) hrcA 103373..104407 (+) 1035 WP_075316634.1 heat-inducible transcriptional repressor HrcA -
  AV644_RS00745 (AV644_00725) grpE 104410..104982 (+) 573 WP_001865751.1 nucleotide exchange factor GrpE -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19447.28 Da        Isoelectric Point: 6.2639

>NTDB_id=165909 AV644_RS00720 WP_001204194.1 100616..101095(+) (comX/sigX) [Streptococcus agalactiae strain GBS-M002]
MRDFEELFDKVKPIVMKLRRNYFVQLWEYDDWIQEGRIVLFRLLEEHPYLLDNESKLFIYFKTKFSNYLNDVLRHQDCQK
RQFNKMPYEEISEVSHYVKSKGLVLDDYIAYRDTLTKVEETLSDIDKEKFEKLISGERFAGKKQFIRDIQPFFNAFKAD

Nucleotide


Download         Length: 480 bp        

>NTDB_id=165909 AV644_RS00720 WP_001204194.1 100616..101095(+) (comX/sigX) [Streptococcus agalactiae strain GBS-M002]
TTGAGAGATTTTGAGGAGTTGTTTGATAAAGTAAAGCCAATCGTAATGAAGCTGAGAAGAAATTATTTTGTTCAACTTTG
GGAATATGATGATTGGATTCAAGAAGGACGTATTGTACTTTTTAGGTTGCTTGAAGAGCATCCGTATTTATTGGATAATG
AAAGCAAACTATTCATTTACTTTAAAACAAAATTTTCAAATTATTTAAACGATGTATTAAGACACCAAGATTGTCAAAAG
CGACAATTTAATAAAATGCCTTATGAAGAAATAAGTGAAGTTAGTCACTATGTTAAGAGTAAAGGACTAGTTTTAGATGA
CTATATTGCTTATCGTGATACTTTAACAAAAGTGGAAGAAACTTTGTCAGATATTGATAAAGAAAAATTTGAAAAACTGA
TTAGTGGTGAACGTTTTGCGGGGAAGAAACAATTCATACGAGATATTCAACCTTTTTTCAATGCTTTTAAAGCGGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

56.688

98.742

0.56
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

52.349

93.711

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

52.349

93.711

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

52.349

93.711

0.491
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

52.349

93.711

0.491
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

52

94.34

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

52

94.34

0.491
  comX/sigX Streptococcus mutans UA159

49.677

97.484

0.484
  comX Streptococcus sobrinus strain NIDR 6715-7

43.59

98.113

0.428
  comX/sigX Streptococcus suis D9

43.226

97.484

0.421
  comX/sigX Streptococcus suis isolate S10

43.226

97.484

0.421
  comX/sigX Streptococcus suis P1/7

43.226

97.484

0.421
  comX Streptococcus thermophilus LMD-9

42.177

92.453

0.39
  comX Streptococcus thermophilus LMG 18311

42.177

92.453

0.39
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

39.869

96.226

0.384
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

39.869

96.226

0.384
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

39.869

96.226

0.384
  comX/comX2 Streptococcus pneumoniae Rx1

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae TIGR4

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae TIGR4

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae Rx1

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae D39

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae D39

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae R6

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae R6

40.397

94.969

0.384
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

39.216

96.226

0.377
  comX Streptococcus salivarius SK126

40.816

92.453

0.377
  comX/sigX Streptococcus salivarius strain HSISS4

40.816

92.453

0.377
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

38.562

96.226

0.371

Multiple sequence alignment