Detailed information NTG0136007

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: SanJ4206_RS00075
• Genome accession: NZ_CP012719
• Coordinates: 15243..15716 (+)
• Length: 157 a.a.
• NCBI ID: WP_022525268.1
• Uniprot ID: A0ABD7NB37
• Organism: Streptococcus anginosus strain J4206
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 10243..20716

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4206_RS00060 (SanJ4206_0012)	tilS	11090..12367 (+)	1278	WP_003029499.1	tRNA lysidine(34) synthetase TilS	-
SanJ4206_RS00065 (SanJ4206_0013)	hpt	12373..12915 (+)	543	WP_003029498.1	hypoxanthine phosphoribosyltransferase	-
SanJ4206_RS00070 (SanJ4206_0014)	ftsH	12936..14906 (+)	1971	WP_003029496.1	ATP-dependent zinc metalloprotease FtsH	-
SanJ4206_RS00075 (SanJ4206_0015)	comR/comR2	15243..15716 (+)	474	WP_022525268.1	sigma-70 family RNA polymerase sigma factor	Regulator
SanJ4206_RS00080	-	15723..16731 (-)	1009	Protein_15	IS30 family transposase	-

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19345.19 Da
• Isoelectric Point: 7.3491

>NTDB_id=136007 SanJ4206_RS00075 WP_022525268.1 15243..15716(+) (comR/comR2) [Streptococcus anginosus strain J4206]
MEFKELYAKVRGIVLKCRREYYVHLWELSDWEQEGMLVLYQLVSRYPQLVEEDHQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide

• Length: 474 bp

>NTDB_id=136007 SanJ4206_RS00075 WP_022525268.1 15243..15716(+) (comR/comR2) [Streptococcus anginosus strain J4206]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTGCTGAAGTGTCGGAGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGAACAAGAGGGCATGTTGGTGCTCTATCAGTTGGTGAGTCGCTATCCGCAGCTAGTAGAAGAAGATC
ATCAGCTTTATGTTTACTATAAGACCAAGTTTCGTAATCATATCTTGGACATCCTCCGTAAGCAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTACGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCCATGATTCGAGAATTAAGAGCCTACTTAAAGGACTATAGCGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0ABD7NB37

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	60.256	99.363	0.599
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	60.256	99.363	0.599
comX/comX2	Streptococcus pneumoniae TIGR4	54.545	98.089	0.535
comX/comX1	Streptococcus pneumoniae TIGR4	54.545	98.089	0.535
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	54.545	98.089	0.535
comX/comX1	Streptococcus pneumoniae R6	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae D39	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae Rx1	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae Rx1	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae D39	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae R6	53.896	98.089	0.529
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	53.896	98.089	0.529
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	53.247	98.089	0.522
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	52.597	98.089	0.516
comX/sigX	Streptococcus mutans UA159	49.359	99.363	0.49
comX/sigX	Streptococcus suis D9	49.032	98.726	0.484
comX/sigX	Streptococcus suis isolate S10	49.032	98.726	0.484
comX/sigX	Streptococcus suis P1/7	49.032	98.726	0.484
comX	Streptococcus salivarius SK126	45.455	98.089	0.446
comX/sigX	Streptococcus salivarius strain HSISS4	44.805	98.089	0.439
comX	Streptococcus thermophilus LMG 18311	44.805	98.089	0.439
comX	Streptococcus thermophilus LMD-9	44.805	98.089	0.439
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.308	99.363	0.42
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.308	99.363	0.42
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.308	99.363	0.42
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	37.821	99.363	0.376
comX	Streptococcus sobrinus strain NIDR 6715-7	38.562	97.452	0.376