Detailed information NTG0125721

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: ID09_RS11310
• Genome accession: NZ_CP008921
• Coordinates: 2291402..2291872 (+)
• Length: 156 a.a.
• NCBI ID: WP_002936602.1
• Uniprot ID: A0A075SE61
• Organism: Streptococcus suis 6407
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2286402..2296872

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ID09_RS11295 (ID09_11585)	tilS	2287251..2288519 (+)	1269	WP_004195367.1	tRNA lysidine(34) synthetase TilS	-
ID09_RS11300 (ID09_11590)	hpt	2288527..2289069 (+)	543	WP_024381313.1	hypoxanthine phosphoribosyltransferase	-
ID09_RS11305 (ID09_11595)	ftsH	2289091..2291064 (+)	1974	WP_024381314.1	ATP-dependent zinc metalloprotease FtsH	-
ID09_RS11310 (ID09_11600)	comX/sigX	2291402..2291872 (+)	471	WP_002936602.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 156 a.a.
• Molecular weight: 19072.97 Da
• Isoelectric Point: 8.9339

>NTDB_id=125721 ID09_RS11310 WP_002936602.1 2291402..2291872(+) (comX/sigX) [Streptococcus suis 6407]
MEFEKVYASVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLEAQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKR
KFDRMPHEDIHELSHAIQSPGLINDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR

Nucleotide

• Length: 471 bp

>NTDB_id=125721 ID09_RS11310 WP_002936602.1 2291402..2291872(+) (comX/sigX) [Streptococcus suis 6407]
ATGGAATTCGAAAAAGTGTACGCAAGCGTCAAAGGTATTGTAAACAAGGCTCGAAAAGAGTTTTACATTAAACTATGGGA
TCGAGATGATTGGGAACAAGAAGGAATGATGACCTTGTTTGAATTATTGGAAGCTCAACCGTGGCTAGTTGATGAACAAG
TTCAATTATATTGTTATTTTAAAGTCAAGTTCAGAAATCGAATCAAGGATCGTATCCGCAAACAGGAAAGTCAAAAACGC
AAGTTTGACCGTATGCCACATGAAGATATTCACGAATTATCTCACGCAATACAATCACCGGGATTGATAAACGATGAACT
ATTAATGCTAAGAGGTGCCTTAAGAGATTATCGAAAAAATCTGAGTAATGATCAACTTGATAAATATGAAAAATTAATTA
GCGGACAATGTTTTAATGGTCGCCGTGAAATGATACGTGATTTACAAATTCATTTGAAAGACTTTCGCTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A075SE61

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus suis D9	100	100	1
comX/sigX	Streptococcus suis isolate S10	99.359	100	0.994
comX/sigX	Streptococcus suis P1/7	99.359	100	0.994
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	49.032	99.359	0.487
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	49.032	99.359	0.487
comX/comX1	Streptococcus pneumoniae TIGR4	46.358	96.795	0.449
comX/comX2	Streptococcus pneumoniae TIGR4	46.358	96.795	0.449
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	45.752	98.077	0.449
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	45.098	98.077	0.442
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	45.098	98.077	0.442
comX/comX1	Streptococcus pneumoniae Rx1	45.695	96.795	0.442
comX/comX2	Streptococcus pneumoniae D39	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae D39	45.695	96.795	0.442
comX/comX2	Streptococcus pneumoniae R6	45.695	96.795	0.442
comX/comX1	Streptococcus pneumoniae R6	45.695	96.795	0.442
comX/comX2	Streptococcus pneumoniae Rx1	45.695	96.795	0.442
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	44.444	98.077	0.436
comX/sigX	Streptococcus mutans UA159	43.226	99.359	0.429
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.645	99.359	0.404
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.645	99.359	0.404
comX	Streptococcus sobrinus strain NIDR 6715-7	40.523	98.077	0.397
comX	Streptococcus thermophilus LMG 18311	40.523	98.077	0.397
comX	Streptococcus thermophilus LMD-9	40.523	98.077	0.397
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	99.359	0.397
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	99.359	0.397
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	99.359	0.397
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	99.359	0.397
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	38.854	100	0.391
comX	Streptococcus salivarius SK126	39.869	98.077	0.391
comX/sigX	Streptococcus salivarius strain HSISS4	39.869	98.077	0.391