Detailed information NTG1171289

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: DYB47_RS01290
• Genome accession: NZ_UHFV01000002
• Coordinates: 217124..217606 (+)
• Length: 160 a.a.
• NCBI ID: WP_003082354.1
• Uniprot ID: G5JW97
• Organism: Streptococcus macacae NCTC 11558
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 212124..222606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS01290 (NCTC11558_00260)	comX/sigX	217124..217606 (+)	483	WP_003082354.1	sigma-70 family RNA polymerase sigma factor	Regulator
DYB47_RS01295 (NCTC11558_00261)	ispE	217692..218540 (+)	849	WP_003079881.1	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	-
DYB47_RS01300 (NCTC11558_00262)	-	218623..219060 (+)	438	WP_003081941.1	zinc-dependent MarR family transcriptional regulator	-
DYB47_RS01305 (NCTC11558_00263)	-	219063..219773 (+)	711	WP_003081503.1	metal ABC transporter ATP-binding protein	-
DYB47_RS01310 (NCTC11558_00264)	-	219763..220578 (+)	816	WP_003078692.1	metal ABC transporter permease	-
DYB47_RS01315 (NCTC11558_00265)	tyrS	220752..222008 (-)	1257	WP_003080919.1	tyrosine--tRNA ligase	-

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19404.52 Da
• Isoelectric Point: 7.3816

>NTDB_id=1171289 DYB47_RS01290 WP_003082354.1 217124..217606(+) (comX/sigX) [Streptococcus macacae NCTC 11558]
MNEDFEDIFEKVKPIVLKIKRHYFIKLWTHDDWYQEGMLILYKLLKERPEVVADDTKLFIYFKTKFSNHIKDVLRKQESK
KRRFNKMPYEEVGDIAHCLSDKGMLLDEYVMFHECLDQFKKSLDDSEQEKFERLIAGEKFAGRQALLKKLRISLNDFKEE

Nucleotide

• Length: 483 bp

>NTDB_id=1171289 DYB47_RS01290 WP_003082354.1 217124..217606(+) (comX/sigX) [Streptococcus macacae NCTC 11558]
ATGAATGAAGATTTTGAAGATATTTTTGAAAAGGTAAAACCAATAGTTTTAAAGATAAAAAGGCATTATTTTATAAAGCT
TTGGACCCATGATGATTGGTATCAAGAGGGGATGCTCATACTCTATAAGCTTTTAAAGGAAAGACCTGAAGTGGTAGCAG
ATGATACTAAATTATTTATTTATTTTAAAACGAAGTTTTCAAATCATATTAAAGATGTATTGAGAAAGCAGGAAAGTAAG
AAAAGGCGTTTTAATAAAATGCCCTATGAAGAAGTTGGGGATATTGCTCACTGCCTTTCGGATAAAGGTATGTTGCTTGA
TGAATATGTTATGTTTCATGAATGTTTAGATCAATTTAAAAAAAGTCTGGATGACAGTGAACAAGAGAAATTTGAACGTT
TAATTGCGGGAGAAAAGTTTGCTGGCAGACAAGCATTGCTTAAAAAACTAAGAATAAGTTTGAATGACTTCAAAGAGGAG
TAA

Domains

No domain identified.

3D structure

• AlphaFold DB: G5JW97

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus mutans UA159	65.409	99.375	0.65
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	46.875	100	0.469
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	46.875	100	0.469
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	46.875	100	0.469
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	46.875	100	0.469
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	46.875	100	0.469
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	46.875	100	0.469
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	47.059	95.625	0.45
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.513	97.5	0.444
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	46.405	95.625	0.444
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	45.752	95.625	0.438
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	45.752	95.625	0.438
comX	Streptococcus salivarius SK126	43.871	96.875	0.425
comX/sigX	Streptococcus salivarius strain HSISS4	43.871	96.875	0.425
comX	Streptococcus thermophilus LMD-9	43.871	96.875	0.425
comX	Streptococcus thermophilus LMG 18311	43.871	96.875	0.425
comX/comX2	Streptococcus pneumoniae TIGR4	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae TIGR4	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae Rx1	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae Rx1	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae D39	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae D39	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae R6	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae R6	45.033	94.375	0.425
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	43.791	95.625	0.419
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	43.791	95.625	0.419
comX/sigX	Streptococcus suis P1/7	41.935	96.875	0.406
comX/sigX	Streptococcus suis isolate S10	41.935	96.875	0.406
comX/sigX	Streptococcus suis D9	41.935	96.875	0.406
comX	Streptococcus sobrinus strain NIDR 6715-7	39.623	99.375	0.394