Detailed information NTG1169935

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: ACLV7H_RS01180
• Genome accession: NZ_OZ217340
• Coordinates: 206112..206585 (+)
• Length: 157 a.a.
• NCBI ID: WP_045591891.1
• Uniprot ID: A0A3R9I308
• Organism: Streptococcus oralis isolate S. oralis A22
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 201112..211585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7H_RS01155 (SORA22_02270)	-	201849..202724 (-)	876	WP_411866143.1	RluA family pseudouridine synthase	-
ACLV7H_RS01160 (SORA22_02280)	pbp2a	202811..205006 (+)	2196	WP_411866144.1	penicillin-binding protein PBP2A	-
ACLV7H_RS01165	rpmG	205059..205211 (+)	153	WP_045591894.1	50S ribosomal protein L33	-
ACLV7H_RS01170 (SORA22_02290)	secE	205221..205397 (+)	177	WP_000505776.1	preprotein translocase subunit SecE	-
ACLV7H_RS01175 (SORA22_02300)	nusG	205455..205991 (+)	537	WP_000376732.1	transcription termination/antitermination protein NusG	-
ACLV7H_RS01180 (SORA22_02310)	comX/comX2	206112..206585 (+)	474	WP_045591891.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19305.15 Da
• Isoelectric Point: 7.8480

>NTDB_id=1169935 ACLV7H_RS01180 WP_045591891.1 206112..206585(+) (comX/comX2) [Streptococcus oralis isolate S. oralis A22]
MNLKDLYEESKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSRNPELLEGERHQLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSMEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide

• Length: 474 bp

>NTDB_id=1169935 ACLV7H_RS01180 WP_045591891.1 206112..206585(+) (comX/comX2) [Streptococcus oralis isolate S. oralis A22]
ATGAATCTAAAAGACTTATATGAAGAAAGTAAGGGAATTGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGACCAGGAAGGCATGTTATGTCTATATGAGCTGGTGAGTCGCAACCCAGAGTTATTAGAGGGCGAAC
GCCATCAACTTTATGTTTGCTTTAAAACAAAATTTAGAAATCGTATTCTGGATTACATCCGTAAACAGGAAAGTCACAAG
CGACGTTTCGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGCCATCGACTAGGAGAAAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAACTACAAATCTAAGCAGAGTATGGAAAAGCAAGAATTAATAGATCGTTTAA
TGGGAGGAGAAGTATTTAGAGGACGGAAAGCTCTATTAAGAGAACTTTCCCTTATTTTTTCAGAATTTCGATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A3R9I308

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	64.286	98.089	0.631
comX/comX2	Streptococcus pneumoniae D39	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae D39	64.286	98.089	0.631
comX/comX2	Streptococcus pneumoniae R6	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae R6	64.286	98.089	0.631
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae Rx1	64.286	98.089	0.631
comX/comX1	Streptococcus pneumoniae TIGR4	63.636	98.089	0.624
comX/comX2	Streptococcus pneumoniae TIGR4	63.636	98.089	0.624
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	62.987	98.089	0.618
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	62.987	98.089	0.618
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	62.987	98.089	0.618
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	53.205	99.363	0.529
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	53.205	99.363	0.529
comX/sigX	Streptococcus mutans UA159	46.711	96.815	0.452
comX/sigX	Streptococcus suis isolate S10	41.401	100	0.414
comX/sigX	Streptococcus suis D9	41.401	100	0.414
comX/sigX	Streptococcus suis P1/7	41.401	100	0.414
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.744	99.363	0.395
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.744	99.363	0.395
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	39.744	99.363	0.395
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	39.744	99.363	0.395
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	39.744	99.363	0.395
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	39.744	99.363	0.395
comX	Streptococcus sobrinus strain NIDR 6715-7	42.657	91.083	0.389
comX	Streptococcus thermophilus LMG 18311	40	95.541	0.382
comX	Streptococcus thermophilus LMD-9	40	95.541	0.382
comX	Streptococcus salivarius SK126	40	95.541	0.382
comX/sigX	Streptococcus salivarius strain HSISS4	40	95.541	0.382
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	37.342	100	0.376