Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   U8955_RS01520 Genome accession   NZ_OY769914
Coordinates   267744..268217 (+) Length   157 a.a.
NCBI ID   WP_197906202.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 262744..273217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS01495 (SDENT7746_01515) - 263483..264358 (-) 876 WP_152417900.1 RluA family pseudouridine synthase -
  U8955_RS01500 (SDENT7746_01520) pbp2a 264445..266640 (+) 2196 WP_038804035.1 penicillin-binding protein PBP2A -
  U8955_RS01505 rpmG 266693..266845 (+) 153 WP_038804034.1 50S ribosomal protein L33 -
  U8955_RS01510 (SDENT7746_01525) secE 266855..267031 (+) 177 WP_000505776.1 preprotein translocase subunit SecE -
  U8955_RS01515 (SDENT7746_01530) nusG 267088..267624 (+) 537 WP_000376732.1 transcription termination/antitermination protein NusG -
  U8955_RS01520 (SDENT7746_01535) comX/comX2 267744..268217 (+) 474 WP_197906202.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19181.07 Da        Isoelectric Point: 8.4595

>NTDB_id=1161699 U8955_RS01520 WP_197906202.1 267744..268217(+) (comX/comX2) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MNLKELYEESKGIVHKCRKEYHLHLWEKEDWDQEGMMCLYELVSHHPELLVGERRRLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKASQGKEKQEQLERLMGGECFKGRKALLGELRVVLSDFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=1161699 U8955_RS01520 WP_197906202.1 267744..268217(+) (comX/comX2) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAATCTGAAAGAACTATACGAAGAAAGCAAGGGGATTGTCCATAAGTGCCGCAAAGAATACCATTTACATCTGTGGGA
GAAAGAGGACTGGGACCAGGAGGGGATGATGTGCCTGTATGAGCTGGTCAGTCACCATCCAGAGTTACTAGTTGGTGAAC
GTCGCCGATTATATGTGTGCTTTAAAACCAAATTCCGCAATCGCATCCTAGACTACATCCGTAAACAGGAAAGTCACAAG
CGCCGTTTCGACAAAGAGCCTTATGAGGAGGTGAGTGAAATCAGCCATCGCCTAGGAGAAAAAGGACTGAGACTGGATGA
TTATTATCTCTTTCATGAGCTTCTAAAGAATTACAAGGCAAGTCAGGGGAAAGAAAAACAAGAACAACTAGAACGTCTGA
TGGGAGGAGAATGTTTCAAAGGACGCAAGGCACTTCTAGGAGAATTAAGAGTGGTATTGAGTGATTTTAGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

65.584

98.089

0.643
  comX/comX2 Streptococcus pneumoniae D39

65.584

98.089

0.643
  comX/comX1 Streptococcus pneumoniae D39

65.584

98.089

0.643
  comX/comX2 Streptococcus pneumoniae R6

65.584

98.089

0.643
  comX/comX1 Streptococcus pneumoniae R6

65.584

98.089

0.643
  comX/comX1 Streptococcus pneumoniae Rx1

65.584

98.089

0.643
  comX/comX2 Streptococcus pneumoniae TIGR4

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae TIGR4

64.935

98.089

0.637
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

64.286

98.089

0.631
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

64.286

98.089

0.631
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

63.636

98.089

0.624
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

62.987

98.089

0.618
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.205

99.363

0.529
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.205

99.363

0.529
  comX/sigX Streptococcus mutans UA159

47.368

96.815

0.459
  comX/sigX Streptococcus suis isolate S10

43.949

100

0.439
  comX/sigX Streptococcus suis D9

43.949

100

0.439
  comX/sigX Streptococcus suis P1/7

43.949

100

0.439
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.241

100

0.395
  comX Streptococcus thermophilus LMG 18311

40

95.541

0.382
  comX Streptococcus thermophilus LMD-9

40

95.541

0.382
  comX/sigX Streptococcus salivarius strain HSISS4

40

95.541

0.382
  comX Streptococcus salivarius SK126

40

95.541

0.382
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

37.821

99.363

0.376
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

37.821

99.363

0.376
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

39.333

95.541

0.376
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

39.333

95.541

0.376
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

39.333

95.541

0.376
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

39.333

95.541

0.376
  comX Streptococcus sobrinus strain NIDR 6715-7

40.559

91.083

0.369

Multiple sequence alignment