Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   QNH68_RS09935 Genome accession   NZ_OX352944
Coordinates   2072708..2073178 (+) Length   156 a.a.
NCBI ID   WP_011921639.1    Uniprot ID   A0A123YDQ1
Organism   Streptococcus suis isolate 861160_LM_H     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2067276..2081647 2072708..2073178 within 0


Gene organization within MGE regions


Location: 2067276..2081647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNH68_RS09915 - 2067276..2068556 (+) 1281 WP_011921635.1 serine hydrolase -
  QNH68_RS09920 tilS 2068557..2069825 (+) 1269 WP_011921636.1 tRNA lysidine(34) synthetase TilS -
  QNH68_RS09925 hpt 2069833..2070375 (+) 543 WP_074390067.1 hypoxanthine phosphoribosyltransferase -
  QNH68_RS09930 ftsH 2070397..2072370 (+) 1974 WP_074390066.1 ATP-dependent zinc metalloprotease FtsH -
  QNH68_RS09935 comX/sigX 2072708..2073178 (+) 471 WP_011921639.1 sigma-70 family RNA polymerase sigma factor Regulator
  QNH68_RS10040 mreC 2080306..2081142 (+) 837 WP_012775464.1 rod shape-determining protein MreC -
  QNH68_RS10045 mreD 2081132..2081647 (+) 516 WP_002935339.1 rod shape-determining protein MreD -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19099.01 Da        Isoelectric Point: 8.9059

>NTDB_id=1155597 QNH68_RS09935 WP_011921639.1 2072708..2073178(+) (comX/sigX) [Streptococcus suis isolate 861160_LM_H]
MEFEKVYASVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLEAQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKR
KFDRMPHEDIYELSHAIQSPGLINDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR

Nucleotide


Download         Length: 471 bp        

>NTDB_id=1155597 QNH68_RS09935 WP_011921639.1 2072708..2073178(+) (comX/sigX) [Streptococcus suis isolate 861160_LM_H]
ATGGAATTCGAAAAAGTGTACGCAAGCGTCAAAGGTATTGTAAACAAGGCTCGAAAAGAGTTTTACATTAAACTATGGGA
TCGAGATGATTGGGAACAAGAAGGAATGATGACCTTGTTTGAATTGTTGGAAGCTCAACCGTGGCTAGTTGATGAACAAG
TTCAATTATATTGTTATTTTAAAGTCAAGTTCAGAAATCGAATCAAAGATCGTATCCGCAAACAGGAAAGTCAAAAACGC
AAGTTTGACCGTATGCCACATGAAGATATTTACGAATTATCTCACGCAATACAATCACCGGGATTGATAAACGATGAATT
ATTAATGTTGAGAGGTGCCTTGAGAGATTATCGAAAAAATCTGAGCAATGATCAACTTGATAAATACGAAAAATTAATTA
GCGGACAATGTTTTAATGGTCGCCGTGAAATGATACGTGATTTACAAATTCATTTGAAAGACTTTCGCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A123YDQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis isolate S10

100

100

1
  comX/sigX Streptococcus suis P1/7

100

100

1
  comX/sigX Streptococcus suis D9

99.359

100

0.994
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.032

99.359

0.487
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.032

99.359

0.487
  comX/comX1 Streptococcus pneumoniae TIGR4

46.358

96.795

0.449
  comX/comX2 Streptococcus pneumoniae TIGR4

46.358

96.795

0.449
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.752

98.077

0.449
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/comX1 Streptococcus pneumoniae Rx1

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae D39

45.695

96.795

0.442
  comX/comX1 Streptococcus pneumoniae D39

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae R6

45.695

96.795

0.442
  comX/comX1 Streptococcus pneumoniae R6

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae Rx1

45.695

96.795

0.442
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

44.444

98.077

0.436
  comX/sigX Streptococcus mutans UA159

43.226

99.359

0.429
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40.645

99.359

0.404
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40.645

99.359

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

40.523

98.077

0.397
  comX Streptococcus thermophilus LMG 18311

40.523

98.077

0.397
  comX Streptococcus thermophilus LMD-9

40.523

98.077

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

99.359

0.397
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

99.359

0.397
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

99.359

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

99.359

0.397
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.854

100

0.391
  comX Streptococcus salivarius SK126

39.869

98.077

0.391
  comX/sigX Streptococcus salivarius strain HSISS4

39.869

98.077

0.391

Multiple sequence alignment