Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   BUC38_RS00455 Genome accession   NZ_LT671674
Coordinates   83961..84431 (+) Length   156 a.a.
NCBI ID   WP_044689744.1    Uniprot ID   A0A0Z8MCL8
Organism   Streptococcus suis strain LS9N     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 78961..89431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUC38_RS00425 recA 80175..81326 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  BUC38_RS00430 spx 81485..81883 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  BUC38_RS00435 - 81990..82256 (+) 267 WP_004195477.1 IreB family regulatory phosphoprotein -
  BUC38_RS00440 ruvX 82256..82675 (+) 420 WP_044689743.1 Holliday junction resolvase RuvX -
  BUC38_RS00445 - 82687..83004 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  BUC38_RS00450 - 83314..83859 (+) 546 Protein_68 nucleotidyltransferase family protein -
  BUC38_RS00455 comX/sigX 83961..84431 (+) 471 WP_044689744.1 sigma-70 family RNA polymerase sigma factor Regulator
  BUC38_RS00465 rpsJ 84697..85005 (+) 309 WP_002939332.1 30S ribosomal protein S10 -
  BUC38_RS00470 rplC 85221..85847 (+) 627 WP_011921686.1 50S ribosomal protein L3 -
  BUC38_RS00475 rplD 85872..86495 (+) 624 WP_004195490.1 50S ribosomal protein L4 -
  BUC38_RS00480 - 86495..86794 (+) 300 WP_004195491.1 50S ribosomal protein L23 -
  BUC38_RS00485 rplB 86812..87645 (+) 834 WP_004195493.1 50S ribosomal protein L2 -
  BUC38_RS00490 rpsS 87896..88177 (+) 282 WP_000533766.1 30S ribosomal protein S19 -
  BUC38_RS00495 rplV 88195..88539 (+) 345 WP_002936662.1 50S ribosomal protein L22 -
  BUC38_RS00500 rpsC 88552..89205 (+) 654 WP_044689746.1 30S ribosomal protein S3 -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19094.70 Da        Isoelectric Point: 6.8779

>NTDB_id=1145968 BUC38_RS00455 WP_044689744.1 83961..84431(+) (comX/sigX) [Streptococcus suis strain LS9N]
MEFEKVYDSVKGIVNKARKEYYIKLWEKEDWDQEGMMTLFELLEDQPWLADEQEQLYCYFKVKFRNRVKDRVRRQESQKR
KFDRMPHEDIHDLSHVIQSPGLVNDELLMLRSALRDYRKNLSDDQLANYEKLISGQSFNGRKNMLRDLQEHLKDFR

Nucleotide


Download         Length: 471 bp        

>NTDB_id=1145968 BUC38_RS00455 WP_044689744.1 83961..84431(+) (comX/sigX) [Streptococcus suis strain LS9N]
ATGGAATTTGAAAAGGTCTATGATAGCGTAAAAGGGATTGTCAACAAGGCTCGAAAAGAGTACTATATTAAATTATGGGA
AAAGGAAGATTGGGATCAAGAGGGCATGATGACCTTATTTGAATTATTGGAAGATCAACCGTGGTTAGCTGATGAGCAAG
AACAGTTGTATTGCTATTTTAAAGTGAAATTTAGAAATCGGGTCAAAGACCGTGTACGCAGACAAGAAAGTCAGAAGCGT
AAGTTTGACCGCATGCCACATGAAGACATTCATGATTTATCTCACGTTATACAATCGCCAGGTTTAGTCAATGACGAGCT
GTTAATGTTGAGAAGTGCCTTAAGAGATTATCGTAAGAATCTCAGCGATGACCAGCTTGCAAATTATGAAAAACTAATTA
GTGGTCAGAGTTTCAATGGTCGTAAGAATATGCTTAGGGATTTACAAGAACATTTAAAGGACTTTCGATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8MCL8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis D9

84.615

100

0.846
  comX/sigX Streptococcus suis isolate S10

83.974

100

0.84
  comX/sigX Streptococcus suis P1/7

83.974

100

0.84
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

50.968

99.359

0.506
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

50.968

99.359

0.506
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

44.444

98.077

0.436
  comX/sigX Streptococcus mutans UA159

43.226

99.359

0.429
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

43.791

98.077

0.429
  comX/comX1 Streptococcus pneumoniae Rx1

44.371

96.795

0.429
  comX/comX2 Streptococcus pneumoniae D39

44.371

96.795

0.429
  comX/comX1 Streptococcus pneumoniae D39

44.371

96.795

0.429
  comX/comX2 Streptococcus pneumoniae R6

44.371

96.795

0.429
  comX/comX1 Streptococcus pneumoniae R6

44.371

96.795

0.429
  comX/comX2 Streptococcus pneumoniae Rx1

44.371

96.795

0.429
  comX/comX2 Streptococcus pneumoniae TIGR4

43.709

96.795

0.423
  comX/comX1 Streptococcus pneumoniae TIGR4

43.709

96.795

0.423
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.137

98.077

0.423
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

41.401

100

0.417
  comX Streptococcus thermophilus LMG 18311

40.523

98.077

0.397
  comX Streptococcus thermophilus LMD-9

40.523

98.077

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.355

99.359

0.391
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.355

99.359

0.391
  comX Streptococcus sobrinus strain NIDR 6715-7

39.869

98.077

0.391
  comX/sigX Streptococcus salivarius strain HSISS4

39.869

98.077

0.391
  comX Streptococcus salivarius SK126

39.869

98.077

0.391
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

38.71

99.359

0.385
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

38.71

99.359

0.385
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

38.71

99.359

0.385
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

38.71

99.359

0.385

Multiple sequence alignment