Detailed information NTG1139602

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: DQM63_RS00085
• Genome accession: NZ_LS483385
• Coordinates: 15419..15904 (+)
• Length: 161 a.a.
• NCBI ID: WP_002899502.1
• Uniprot ID: A0A3R9H2A4
• Organism: Streptococcus sanguinis strain NCTC7863
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 10419..20904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM63_RS00060 (NCTC7863_00011)	tilS	11131..12408 (+)	1278	WP_002899506.1	tRNA lysidine(34) synthetase TilS	-
DQM63_RS00065 (NCTC7863_00012)	hpt	12413..12955 (+)	543	WP_032909165.1	hypoxanthine phosphoribosyltransferase	-
DQM63_RS00070 (NCTC7863_00013)	ftsH	12973..14952 (+)	1980	WP_002894312.1	ATP-dependent zinc metalloprotease FtsH	-
DQM63_RS00085 (NCTC7863_00016)	comR/comR2	15419..15904 (+)	486	WP_002899502.1	transcriptional regulator	Regulator

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 19980.85 Da
• Isoelectric Point: 9.1020

>NTDB_id=1139602 DQM63_RS00085 WP_002899502.1 15419..15904(+) (comR/comR2) [Streptococcus sanguinis strain NCTC7863]
MDFRTTYEKVKWIVWKCKKDYYIHLWEHSDWDQEGMLVLYELLLKEKGIENDEEKLYRYFKTKFRNHIHDKIRKQESQKR
KLDRQPYEEVSEIGHRLKSKELFLDELVAFREAIDNYKRTLDDVGLDNYQRLMSNERFKGRRAMLKDLKNHLKDFQDNTI
L

Nucleotide

• Length: 486 bp

>NTDB_id=1139602 DQM63_RS00085 WP_002899502.1 15419..15904(+) (comR/comR2) [Streptococcus sanguinis strain NCTC7863]
ATGGATTTTAGAACTACTTATGAGAAGGTGAAATGGATAGTTTGGAAGTGTAAGAAAGATTACTATATACACTTGTGGGA
ACATAGTGATTGGGATCAAGAAGGAATGTTAGTTTTATACGAACTTCTACTTAAAGAAAAAGGAATTGAAAACGATGAGG
AAAAACTCTATCGTTATTTCAAAACAAAATTCAGAAATCATATACATGATAAAATTCGTAAACAAGAAAGCCAAAAGCGC
AAATTGGACCGCCAGCCTTATGAAGAAGTGAGTGAGATTGGTCATCGTTTGAAGTCAAAAGAGTTGTTTCTAGATGAGTT
AGTTGCCTTCAGAGAAGCGATTGACAATTATAAAAGAACTCTTGATGATGTTGGATTGGATAATTATCAGAGGTTGATGA
GCAACGAGCGCTTTAAAGGAAGAAGAGCCATGCTTAAAGATTTAAAAAATCACTTAAAAGATTTTCAAGATAATACGATT
TTATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A3R9H2A4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comX/comX1	Streptococcus pneumoniae D39	50.327	95.031	0.478
comX/comX2	Streptococcus pneumoniae Rx1	50.327	95.031	0.478
comX/comX1	Streptococcus pneumoniae Rx1	50.327	95.031	0.478
comX/comX2	Streptococcus pneumoniae D39	50.327	95.031	0.478
comX/comX2	Streptococcus pneumoniae R6	50.327	95.031	0.478
comX/comX1	Streptococcus pneumoniae R6	50.327	95.031	0.478
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	48.408	97.516	0.472
comX/sigX	Streptococcus suis D9	48.718	96.894	0.472
comX/sigX	Streptococcus suis isolate S10	48.718	96.894	0.472
comX/sigX	Streptococcus suis P1/7	48.718	96.894	0.472
comX/comX2	Streptococcus pneumoniae TIGR4	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae TIGR4	49.673	95.031	0.472
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	47.771	97.516	0.466
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	47.134	97.516	0.46
comX/sigX	Streptococcus mutans UA159	47.436	96.894	0.46
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	45.86	97.516	0.447
comX	Streptococcus sobrinus strain NIDR 6715-7	41.212	100	0.422
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.405	98.137	0.416
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.405	98.137	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.405	98.137	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.405	98.137	0.416
comX	Streptococcus thermophilus LMG 18311	42.308	96.894	0.41
comX	Streptococcus thermophilus LMD-9	42.308	96.894	0.41
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.772	98.137	0.41
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.772	98.137	0.41
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.241	98.137	0.385
comX/sigX	Streptococcus salivarius strain HSISS4	40.523	95.031	0.385
comX	Streptococcus salivarius SK126	40.523	95.031	0.385