Detailed information    

insolico Bioinformatically predicted

Overview


Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM52_RS01970 Genome accession   NZ_LS483367
Coordinates   357059..357541 (+) Length   160 a.a.
NCBI ID   WP_003057148.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 357458..358669 357059..357541 flank -83


Gene organization within MGE regions


Location: 357059..358669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM52_RS01970 (NCTC5371_00395) comX/sigX/comX2/sigX2 357059..357541 (+) 483 WP_003057148.1 sigma-70 family RNA polymerase sigma factor Regulator
  DQM52_RS01975 (NCTC5371_00396) - 357740..358669 (-) 930 Protein_323 IS30-like element IS1239 family transposase -

Sequence


Protein


Download         Length: 160 a.a.        Molecular weight: 18997.80 Da        Isoelectric Point: 8.3220

>NTDB_id=1138829 DQM52_RS01970 WP_003057148.1 357059..357541(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
MSLETGEVFEKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVKLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQ
KRQFDKMAYEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSEADRKQFQALVRGERFKGRQALLRKVRPYFSGFDQG

Nucleotide


Download         Length: 483 bp        

>NTDB_id=1138829 DQM52_RS01970 WP_003057148.1 357059..357541(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
ATGTCGTTAGAGACAGGGGAGGTTTTTGAGAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACTTACAGTT
GTGGGAGACGGATGACTGGTTACAAGAGGGGCATTTGGTTTTAGTGAAGTTGTTGGAACGTCACCCAGAGTTAGTAGGAG
ATGAGGCTCGCTTGTATCGGTATTTTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAG
AAACGCCAGTTTGACAAGATGGCTTATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGCGGGTTATGGTTGGA
TGATTATGTGGCCTATCGGGAGGTTTTAGTACAAGTGGAGGAGGCCTTAAGCGAAGCGGATCGGAAGCAGTTTCAGGCCT
TAGTGAGAGGGGAACGGTTCAAGGGGCGTCAGGCTTTGCTTAGGAAGGTTCGTCCTTACTTTAGTGGGTTTGACCAAGGG
TGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

74.843

99.375

0.744

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

74.843

99.375

0.744

  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

74.214

99.375

0.738

  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

74.214

99.375

0.738

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

73.585

99.375

0.731

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

73.585

99.375

0.731

  comX/sigX Streptococcus mutans UA159

50

93.75

0.469

  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

93.75

0.456

  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

46.711

95

0.444

  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.395

95

0.431

  comX/comX1 Streptococcus pneumoniae Rx1

45.033

94.375

0.425

  comX/comX2 Streptococcus pneumoniae TIGR4

45.033

94.375

0.425

  comX/comX1 Streptococcus pneumoniae TIGR4

45.033

94.375

0.425

  comX/comX2 Streptococcus pneumoniae Rx1

45.033

94.375

0.425

  comX/comX2 Streptococcus pneumoniae D39

45.033

94.375

0.425

  comX/comX1 Streptococcus pneumoniae D39

45.033

94.375

0.425

  comX/comX2 Streptococcus pneumoniae R6

45.033

94.375

0.425

  comX/comX1 Streptococcus pneumoniae R6

45.033

94.375

0.425

  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419

  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

44.079

95

0.419

  comX Streptococcus sobrinus strain NIDR 6715-7

44.079

95

0.419

  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419

  comX Streptococcus thermophilus LMG 18311

43.709

94.375

0.413

  comX Streptococcus thermophilus LMD-9

43.709

94.375

0.413

  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.421

95

0.412

  comX/sigX Streptococcus salivarius strain HSISS4

41.722

94.375

0.394

  comX Streptococcus salivarius SK126

41.722

94.375

0.394

  comX/sigX Streptococcus suis D9

38.71

96.875

0.375

  comX/sigX Streptococcus suis isolate S10

38.71

96.875

0.375

  comX/sigX Streptococcus suis P1/7

38.71

96.875

0.375


Multiple sequence alignment