Detailed information NTG1138210

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: DQL02_RS01500
• Genome accession: NZ_LS483355
• Coordinates: 274472..274957 (+)
• Length: 161 a.a.
• NCBI ID: WP_002988129.1
• Uniprot ID: A0A6C2W3T2
• Organism: Streptococcus pyogenes strain NCTC12067
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 269472..279957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL02_RS01500 (NCTC12067_00298)	comX/sigX/comX2/sigX2	274472..274957 (+)	486	WP_002988129.1	competence protein ComX	Regulator
DQL02_RS01505 (NCTC12067_00299)	-	275516..276043 (+)	528	WP_002991099.1	YqeG family HAD IIIA-type phosphatase	-
DQL02_RS01510 (NCTC12067_00300)	yqeH	276043..277161 (+)	1119	WP_031488554.1	ribosome biogenesis GTPase YqeH	-
DQL02_RS01515 (NCTC12067_00301)	yhbY	277186..277494 (+)	309	WP_002991094.1	ribosome assembly RNA-binding protein YhbY	-
DQL02_RS01520 (NCTC12067_00302)	-	277563..278195 (+)	633	WP_031488555.1	nicotinate-nucleotide adenylyltransferase	-
DQL02_RS01525 (NCTC12067_00303)	yqeK	278192..278785 (+)	594	WP_002985989.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
DQL02_RS01530 (NCTC12067_00304)	rsfS	278809..279162 (+)	354	WP_063510294.1	ribosome silencing factor	-
DQL02_RS01535 (NCTC12067_00305)	-	279210..279953 (+)	744	WP_014407307.1	class I SAM-dependent DNA methyltransferase	-

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 19669.68 Da
• Isoelectric Point: 9.5784

>NTDB_id=1138210 DQL02_RS01500 WP_002988129.1 274472..274957(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC12067]
MSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQESQ
KRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGERFKGRRALLRKISPYFKEFAQQ
L

Nucleotide

• Length: 486 bp

>NTDB_id=1138210 DQL02_RS01500 WP_002988129.1 274472..274957(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC12067]
ATGTCGATAGAGACAAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATT
GTGGGATAGAGATGACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGG
AAGAAGAGCGTTTATATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAA
AAGCGTCAGTTCCATAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGA
CGACTATGTGGCTTATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCAC
TTATCAGGGGCGAACGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAG
TTGTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6C2W3T2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	100	100	1
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	100	100	1
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	99.379	100	0.994
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	99.379	100	0.994
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	99.379	100	0.994
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	99.379	100	0.994
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	49.333	93.168	0.46
comX	Streptococcus sobrinus strain NIDR 6715-7	46.104	95.652	0.441
comX/sigX	Streptococcus mutans UA159	44.444	95.031	0.422
comX	Streptococcus thermophilus LMD-9	42.667	93.168	0.398
comX	Streptococcus salivarius SK126	42.667	93.168	0.398
comX	Streptococcus thermophilus LMG 18311	42.667	93.168	0.398
comX/sigX	Streptococcus salivarius strain HSISS4	42.667	93.168	0.398
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	42.953	92.547	0.398
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	42.282	92.547	0.391
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	40.26	95.652	0.385
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	40.26	95.652	0.385
comX/sigX	Streptococcus suis isolate S10	40	96.273	0.385
comX/sigX	Streptococcus suis D9	40	96.273	0.385
comX/sigX	Streptococcus suis P1/7	40	96.273	0.385
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	40.94	92.547	0.379
comX/comX2	Streptococcus pneumoniae Rx1	40	93.168	0.373
comX/comX2	Streptococcus pneumoniae R6	40	93.168	0.373
comX/comX1	Streptococcus pneumoniae R6	40	93.168	0.373
comX/comX2	Streptococcus pneumoniae TIGR4	40	93.168	0.373
comX/comX1	Streptococcus pneumoniae TIGR4	40	93.168	0.373
comX/comX2	Streptococcus pneumoniae D39	40	93.168	0.373
comX/comX1	Streptococcus pneumoniae Rx1	40	93.168	0.373
comX/comX1	Streptococcus pneumoniae D39	40	93.168	0.373
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	40.268	92.547	0.373