Detailed information NTG1137673

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: DQM73_RS00085
• Genome accession: NZ_LS483346
• Coordinates: 15415..15900 (+)
• Length: 161 a.a.
• NCBI ID: WP_002927434.1
• Uniprot ID: A0A2X3VMY3
• Organism: Streptococcus sanguinis strain NCTC11085
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 10415..20900

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM73_RS00060 (NCTC11085_00011)	tilS	11124..12401 (+)	1278	WP_002927433.1	tRNA lysidine(34) synthetase TilS	-
DQM73_RS00065 (NCTC11085_00012)	hpt	12406..12948 (+)	543	WP_032908267.1	hypoxanthine phosphoribosyltransferase	-
DQM73_RS00070 (NCTC11085_00013)	ftsH	12966..14945 (+)	1980	WP_002894312.1	ATP-dependent zinc metalloprotease FtsH	-
DQM73_RS00085 (NCTC11085_00016)	comR/comR2	15415..15900 (+)	486	WP_002927434.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 19936.84 Da
• Isoelectric Point: 9.3626

>NTDB_id=1137673 DQM73_RS00085 WP_002927434.1 15415..15900(+) (comR/comR2) [Streptococcus sanguinis strain NCTC11085]
MDFRTTYEKVKWIVWKCKKDYYIHLWEHSDWEQEGMLVLYELLLKEKGIENDEEKLYRYFKTKFRNHIHDKIRKQESQKR
KLDRQPYEEVSEIGHRLKSKELFLDELVAFREAIGNYKRTLDDVGLDNYQRLMSNERFKGRRAMLKDLKNHLKDFQDNTI
L

Nucleotide

• Length: 486 bp

>NTDB_id=1137673 DQM73_RS00085 WP_002927434.1 15415..15900(+) (comR/comR2) [Streptococcus sanguinis strain NCTC11085]
ATGGATTTTAGAACTACTTATGAGAAGGTGAAATGGATAGTTTGGAAGTGTAAGAAAGACTATTATATTCATTTGTGGGA
ACATAGTGATTGGGAGCAAGAAGGAATGTTGGTTTTATACGAACTTCTGCTTAAAGAAAAAGGAATTGAAAACGATGAGG
AAAAACTCTATCGTTATTTCAAAACAAAATTCAGAAATCATATACATGATAAAATTCGTAAACAAGAAAGCCAAAAGCGC
AAATTGGACCGCCAGCCTTATGAAGAAGTGAGTGAGATTGGTCATCGACTAAAATCAAAAGAACTGTTTCTAGATGAGTT
AGTTGCTTTCAGAGAGGCAATTGGTAATTATAAAAGAACTCTTGATGATGTTGGCTTGGATAATTATCAGAGGTTGATGA
GCAACGAGCGCTTTAAAGGAAGAAGAGCTATGCTCAAAGATTTGAAAAATCACTTAAAAGATTTTCAAGATAATACAATT
TTATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A2X3VMY3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	65.806	96.273	0.634
comX/comX2	Streptococcus pneumoniae TIGR4	50.327	95.031	0.478
comX/comX1	Streptococcus pneumoniae TIGR4	50.327	95.031	0.478
comX/sigX	Streptococcus suis isolate S10	49.359	96.894	0.478
comX/sigX	Streptococcus suis D9	49.359	96.894	0.478
comX/sigX	Streptococcus suis P1/7	49.359	96.894	0.478
comX/comX2	Streptococcus pneumoniae Rx1	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae Rx1	49.673	95.031	0.472
comX/comX2	Streptococcus pneumoniae D39	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae D39	49.673	95.031	0.472
comX/comX2	Streptococcus pneumoniae R6	49.673	95.031	0.472
comX/comX1	Streptococcus pneumoniae R6	49.673	95.031	0.472
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	47.771	97.516	0.466
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	47.134	97.516	0.46
comX/sigX	Streptococcus mutans UA159	47.436	96.894	0.46
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	46.497	97.516	0.453
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	45.223	97.516	0.441
comX	Streptococcus sobrinus strain NIDR 6715-7	43.59	96.894	0.422
comX	Streptococcus thermophilus LMD-9	42.949	96.894	0.416
comX	Streptococcus thermophilus LMG 18311	42.949	96.894	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.405	98.137	0.416
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.405	98.137	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.405	98.137	0.416
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.405	98.137	0.416
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.772	98.137	0.41
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.772	98.137	0.41
comX/sigX	Streptococcus salivarius strain HSISS4	41.176	95.031	0.391
comX	Streptococcus salivarius SK126	41.176	95.031	0.391
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.49	97.516	0.385