Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQL21_RS07755 Genome accession   NZ_LS483343
Coordinates   1497337..1497819 (-) Length   160 a.a.
NCBI ID   WP_018030395.1    Uniprot ID   A0A2X3VHY4
Organism   Streptococcus ferus strain NCTC12278     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1492337..1502819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS07725 (NCTC12278_01545) - 1492399..1492623 (-) 225 WP_018030389.1 acyl carrier protein -
  DQL21_RS07730 (NCTC12278_01546) - 1492682..1493656 (-) 975 WP_018030390.1 beta-ketoacyl-ACP synthase III -
  DQL21_RS07735 (NCTC12278_01547) - 1493653..1494090 (-) 438 WP_026161942.1 MarR family winged helix-turn-helix transcriptional regulator -
  DQL21_RS07740 (NCTC12278_01548) - 1494231..1495022 (-) 792 WP_018030392.1 enoyl-CoA hydratase -
  DQL21_RS07745 (NCTC12278_01549) - 1495168..1495824 (-) 657 WP_018030393.1 HAD family phosphatase -
  DQL21_RS07750 (NCTC12278_01550) - 1495978..1497330 (+) 1353 WP_026161944.1 aspartate kinase -
  DQL21_RS07755 (NCTC12278_01551) comX/sigX/comX2/sigX2 1497337..1497819 (-) 483 WP_018030395.1 sigma-70 family RNA polymerase sigma factor Regulator
  DQL21_RS07765 (NCTC12278_01553) - 1498290..1498742 (+) 453 WP_018031152.1 DUF1772 domain-containing protein -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18836.40 Da        Isoelectric Point: 6.1467

>NTDB_id=1137609 DQL21_RS07755 WP_018030395.1 1497337..1497819(-) (comX/sigX/comX2/sigX2) [Streptococcus ferus strain NCTC12278]
MSEDFEALFQKVRPIVYKFRRHYHHIQLWDRHDWEQEGMITLFQLVSSCPEVLENEAKLFIYFKTKFSNHLKDTLRKQLS
QKRQFHQMAYEEIGEVGHSVAQGGLVLDEYVAYQEALAAYREGLSAEKSDQLNALIAGECFKGRAAMLRELEAVFQDFRE

Nucleotide


Download         Length: 483 bp        

>NTDB_id=1137609 DQL21_RS07755 WP_018030395.1 1497337..1497819(-) (comX/sigX/comX2/sigX2) [Streptococcus ferus strain NCTC12278]
ATGTCAGAAGATTTTGAAGCCTTATTTCAGAAGGTGCGCCCTATTGTTTATAAGTTTAGGCGGCATTATCATCATATCCA
GTTATGGGATCGCCATGATTGGGAGCAGGAGGGAATGATAACCTTGTTTCAGCTCGTCAGTTCCTGTCCTGAAGTCCTTG
AGAATGAGGCTAAACTTTTTATTTATTTCAAAACGAAGTTTTCTAATCATTTGAAAGACACGCTTCGCAAACAGCTGAGT
CAGAAACGGCAGTTTCATCAGATGGCTTATGAAGAGATTGGGGAGGTTGGTCACAGCGTGGCTCAGGGCGGTTTAGTTTT
GGATGAATACGTGGCCTATCAGGAGGCTTTAGCAGCTTATCGTGAGGGGCTAAGTGCTGAAAAGTCTGATCAGCTGAATG
CCTTGATTGCTGGTGAATGTTTCAAGGGCCGTGCTGCTATGCTTCGGGAGTTGGAGGCTGTTTTTCAAGACTTCAGGGAA
TGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3VHY4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

55.696

98.75

0.55
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

55.696

98.75

0.55
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

55.696

98.75

0.55
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

55.696

98.75

0.55
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

55.696

98.75

0.55
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

55.696

98.75

0.55
  comX/sigX Streptococcus mutans UA159

51.875

100

0.519
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.682

98.125

0.488
  comX Streptococcus thermophilus LMG 18311

46.104

96.25

0.444
  comX Streptococcus thermophilus LMD-9

46.104

96.25

0.444
  comX/sigX Streptococcus suis isolate S10

44.872

97.5

0.438
  comX/sigX Streptococcus suis D9

44.872

97.5

0.438
  comX/sigX Streptococcus suis P1/7

44.872

97.5

0.438
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

44.805

96.25

0.431
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

44.805

96.25

0.431
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

44.156

96.25

0.425
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

44.156

96.25

0.425
  comX Streptococcus salivarius SK126

45.333

93.75

0.425
  comX/sigX Streptococcus salivarius strain HSISS4

45.333

93.75

0.425
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

43.506

96.25

0.419
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

43.506

96.25

0.419
  comX/comX1 Streptococcus pneumoniae TIGR4

43.046

94.375

0.406
  comX/comX2 Streptococcus pneumoniae TIGR4

43.046

94.375

0.406
  comX/comX2 Streptococcus pneumoniae D39

42.384

94.375

0.4
  comX/comX1 Streptococcus pneumoniae D39

42.384

94.375

0.4
  comX/comX2 Streptococcus pneumoniae R6

42.384

94.375

0.4
  comX/comX1 Streptococcus pneumoniae R6

42.384

94.375

0.4
  comX/comX2 Streptococcus pneumoniae Rx1

42.384

94.375

0.4
  comX/comX1 Streptococcus pneumoniae Rx1

42.384

94.375

0.4
  comX Streptococcus sobrinus strain NIDR 6715-7

39.744

97.5

0.388

Multiple sequence alignment