Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQL21_RS01520 Genome accession   NZ_LS483343
Coordinates   274697..275179 (+) Length   160 a.a.
NCBI ID   WP_018031080.1    Uniprot ID   A0A2X3VIG9
Organism   Streptococcus ferus strain NCTC12278     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 269697..280179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS01520 (NCTC12278_00290) comX/sigX/comX2/sigX2 274697..275179 (+) 483 WP_018031080.1 sigma-70 family RNA polymerase sigma factor Regulator
  DQL21_RS01530 (NCTC12278_00292) ispE 275659..276507 (+) 849 WP_018031081.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
  DQL21_RS01535 (NCTC12278_00293) - 276595..277035 (+) 441 WP_111703007.1 zinc-dependent MarR family transcriptional regulator -
  DQL21_RS01540 (NCTC12278_00294) - 277037..277747 (+) 711 WP_018031082.1 metal ABC transporter ATP-binding protein -
  DQL21_RS01545 (NCTC12278_00295) - 277737..278549 (+) 813 WP_018031083.1 metal ABC transporter permease -
  DQL21_RS01550 (NCTC12278_00296) tyrS 278589..279845 (-) 1257 WP_018031084.1 tyrosine--tRNA ligase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18882.49 Da        Isoelectric Point: 6.1456

>NTDB_id=1137568 DQL21_RS01520 WP_018031080.1 274697..275179(+) (comX/sigX/comX2/sigX2) [Streptococcus ferus strain NCTC12278]
MSEDFEALFQKVRPIVYKFRRHYHHIQLWDRHDWEQEGMITLFQLVSSCPEVLENEAKLFIYFKTKFSNHLKDTLRKQLS
QKRQFHQMAYEEIGEVGHSVAQCGLVLDEYVAYQEALAAYREGLSAEKSDQLNALIAGECFKGRAAMLRELEAVFQDFRE

Nucleotide


Download         Length: 483 bp        

>NTDB_id=1137568 DQL21_RS01520 WP_018031080.1 274697..275179(+) (comX/sigX/comX2/sigX2) [Streptococcus ferus strain NCTC12278]
ATGTCAGAAGATTTTGAAGCCTTATTTCAGAAGGTGCGCCCTATTGTTTATAAGTTTAGGCGGCATTATCATCATATCCA
GTTATGGGATCGCCATGATTGGGAGCAGGAGGGAATGATAACCTTGTTTCAGCTCGTCAGTTCCTGTCCTGAAGTCCTTG
AGAATGAGGCTAAACTTTTTATTTATTTCAAAACGAAGTTTTCTAATCATTTGAAAGACACGCTTCGCAAACAGCTGAGT
CAGAAACGGCAGTTTCATCAGATGGCTTATGAAGAGATTGGGGAGGTTGGTCACAGTGTGGCTCAGTGCGGTTTAGTTTT
GGATGAATACGTGGCCTATCAGGAGGCTTTAGCAGCTTATCGTGAGGGGCTAAGTGCTGAAAAGTCTGATCAGCTGAATG
CTTTGATTGCTGGTGAATGTTTCAAGGGCCGTGCTGCTATGCTTCGGGAGTTGGAGGCTGTTTTTCAAGACTTCAGGGAA
TAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3VIG9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

55.696

98.75

0.55
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

55.696

98.75

0.55
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

55.696

98.75

0.55
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

55.696

98.75

0.55
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

55.696

98.75

0.55
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

55.696

98.75

0.55
  comX/sigX Streptococcus mutans UA159

51.25

100

0.513
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.682

98.125

0.488
  comX Streptococcus thermophilus LMG 18311

46.104

96.25

0.444
  comX Streptococcus thermophilus LMD-9

46.104

96.25

0.444
  comX/sigX Streptococcus suis P1/7

44.872

97.5

0.438
  comX/sigX Streptococcus suis isolate S10

44.872

97.5

0.438
  comX/sigX Streptococcus suis D9

44.872

97.5

0.438
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

44.156

96.25

0.425
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

44.156

96.25

0.425
  comX/sigX Streptococcus salivarius strain HSISS4

45.333

93.75

0.425
  comX Streptococcus salivarius SK126

45.333

93.75

0.425
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.506

96.25

0.419
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

43.506

96.25

0.419
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

43.506

96.25

0.419
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

43.506

96.25

0.419
  comX/comX1 Streptococcus pneumoniae TIGR4

42.384

94.375

0.4
  comX/comX2 Streptococcus pneumoniae TIGR4

42.384

94.375

0.4
  comX/comX2 Streptococcus pneumoniae D39

41.722

94.375

0.394
  comX/comX1 Streptococcus pneumoniae D39

41.722

94.375

0.394
  comX/comX2 Streptococcus pneumoniae R6

41.722

94.375

0.394
  comX/comX1 Streptococcus pneumoniae R6

41.722

94.375

0.394
  comX/comX2 Streptococcus pneumoniae Rx1

41.722

94.375

0.394
  comX/comX1 Streptococcus pneumoniae Rx1

41.722

94.375

0.394
  comX Streptococcus sobrinus strain NIDR 6715-7

39.744

97.5

0.388

Multiple sequence alignment