Detailed information NTG1136186

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: DQM44_RS01640
• Genome accession: NZ_LS483318
• Coordinates: 297761..298243 (+)
• Length: 160 a.a.
• NCBI ID: WP_111711550.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	298374..299369	297761..298243	flank	131

Gene organization within MGE regions

Location: 297761..299369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM44_RS01640 (NCTC5370_00337)	comX/sigX/comX2/sigX2	297761..298243 (+)	483	WP_111711550.1	sigma-70 family RNA polymerase sigma factor	Regulator
DQM44_RS01645 (NCTC5370_00338)	-	298374..299369 (-)	996	WP_111711551.1	IS30-like element IS1239 family transposase	-

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19027.82 Da
• Isoelectric Point: 8.3220

>NTDB_id=1136186 DQM44_RS01640 WP_111711550.1 297761..298243(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MSLETGEVFEKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVKLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQ
KRQFDKMAYEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSETDRKQFQALVRGERFKGRQALLRKVRPYFSGFDQG

Nucleotide

• Length: 483 bp

>NTDB_id=1136186 DQM44_RS01640 WP_111711550.1 297761..298243(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
ATGTCGTTAGAGACAGGGGAGGTTTTTGAGAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACTTACAGTT
GTGGGAGACGGATGACTGGTTACAAGAGGGGCATTTGGTTTTAGTGAAGTTGTTGGAACGTCACCCAGAGTTAGTAGGAG
ATGAGGCTCGCTTGTATCGGTATTTTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAG
AAACGCCAGTTTGACAAGATGGCTTATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGCGGGTTATGGTTGGA
TGATTATGTGGCCTATCGGGAGGTTTTAGTACAAGTGGAGGAGGCCTTAAGCGAAACGGATCGGAAGCAGTTTCAGGCCT
TAGTGAGAGGGGAACGGTTCAAGGGGCGTCAGGCTTTGCTTAGGAAGGTTCGTCCTTACTTTAGTGGGTTTGACCAAGGG
TGA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	74.843	99.375	0.744
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	74.843	99.375	0.744
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	74.214	99.375	0.738
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	74.214	99.375	0.738
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	73.585	99.375	0.731
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	73.585	99.375	0.731
comX/sigX	Streptococcus mutans UA159	49.342	95	0.469
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.667	93.75	0.456
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	46.711	95	0.444
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	45.395	95	0.431
comX/comX1	Streptococcus pneumoniae Rx1	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae TIGR4	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae TIGR4	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae Rx1	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae D39	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae D39	45.033	94.375	0.425
comX/comX2	Streptococcus pneumoniae R6	45.033	94.375	0.425
comX/comX1	Streptococcus pneumoniae R6	45.033	94.375	0.425
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	44.079	95	0.419
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	44.079	95	0.419
comX	Streptococcus sobrinus strain NIDR 6715-7	44.079	95	0.419
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	44.079	95	0.419
comX	Streptococcus thermophilus LMG 18311	43.709	94.375	0.413
comX	Streptococcus thermophilus LMD-9	43.709	94.375	0.413
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	43.421	95	0.412
comX/sigX	Streptococcus salivarius strain HSISS4	41.722	94.375	0.394
comX	Streptococcus salivarius SK126	41.722	94.375	0.394
comX/sigX	Streptococcus suis D9	38.71	96.875	0.375
comX/sigX	Streptococcus suis isolate S10	38.71	96.875	0.375
comX/sigX	Streptococcus suis P1/7	38.71	96.875	0.375