Detailed information NTG1127537

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: FGL12_RS10795
• Genome accession: NZ_LR594041
• Coordinates: 2205935..2206417 (-)
• Length: 160 a.a.
• NCBI ID: WP_012130755.1
• Uniprot ID: Q6XLQ2
• Organism: Streptococcus gordonii strain NCTC9124
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2200935..2211417

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL12_RS10795 (NCTC9124_02179)	comR/comR2	2205935..2206417 (-)	483	WP_012130755.1	sigma-70 family RNA polymerase sigma factor	Regulator
FGL12_RS10810 (NCTC9124_02182)	ftsH	2206948..2208930 (-)	1983	WP_012131068.1	ATP-dependent zinc metalloprotease FtsH	-
FGL12_RS10815 (NCTC9124_02183)	hpt	2208949..2209491 (-)	543	WP_012131069.1	hypoxanthine phosphoribosyltransferase	-
FGL12_RS10820 (NCTC9124_02184)	tilS	2209496..2210773 (-)	1278	WP_012131070.1	tRNA lysidine(34) synthetase TilS	-

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19950.92 Da
• Isoelectric Point: 9.6140

>NTDB_id=1127537 FGL12_RS10795 WP_012130755.1 2205935..2206417(-) (comR/comR2) [Streptococcus gordonii strain NCTC9124]
MKFEDVYKQVEGIVKRCYKDYYLHLWEYADWRQEGMLVLYELLKSHPNLLEDQPRLYRYFKTKFRNRIHDLIRRQESQKR
KLDRQPYEEVSEIGHRLRMKELYLDELVAFRSAMSEYRSRLSPEEAKQYERLMADERFKGRKAMLKDLSYHLRDFNPRLD

Nucleotide

• Length: 483 bp

>NTDB_id=1127537 FGL12_RS10795 WP_012130755.1 2205935..2206417(-) (comR/comR2) [Streptococcus gordonii strain NCTC9124]
ATGAAGTTTGAGGACGTATACAAACAAGTTGAAGGGATAGTCAAGCGATGTTATAAAGATTATTATCTGCACTTATGGGA
GTATGCAGATTGGAGGCAGGAAGGGATGTTGGTGTTGTACGAATTGTTAAAAAGTCACCCCAACCTACTAGAAGATCAAC
CACGACTGTACCGTTACTTCAAGACCAAGTTTCGGAACAGAATTCATGATTTGATTCGTCGCCAAGAGAGTCAAAAACGG
AAATTGGACAGGCAACCCTATGAAGAGGTCAGCGAGATAGGTCATCGTTTAAGAATGAAAGAGCTTTATCTAGATGAACT
GGTAGCCTTTAGAAGTGCCATGTCAGAGTATAGAAGCCGTCTCAGCCCAGAAGAGGCAAAACAATATGAGCGTCTGATGG
CAGATGAAAGATTCAAAGGACGTAAGGCAATGCTCAAAGATCTGTCTTATCACTTAAGGGATTTCAATCCCCGTTTAGAT
TAA

Domains

No domain identified.

3D structure

• AlphaFold DB: Q6XLQ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	100	100	1
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	100	100	1
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	50	97.5	0.488
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	49.359	97.5	0.481
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	49.359	97.5	0.481
comX/comX1	Streptococcus pneumoniae TIGR4	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae Rx1	48.718	97.5	0.475
comX/comX1	Streptococcus pneumoniae Rx1	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae D39	48.718	97.5	0.475
comX/comX1	Streptococcus pneumoniae D39	48.718	97.5	0.475
comX/comX1	Streptococcus pneumoniae R6	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae R6	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae TIGR4	48.718	97.5	0.475
comX/sigX	Streptococcus suis isolate S10	49.032	96.875	0.475
comX/sigX	Streptococcus suis P1/7	49.032	96.875	0.475
comX/sigX	Streptococcus suis D9	49.032	96.875	0.475
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	48.077	97.5	0.469
comX/sigX	Streptococcus mutans UA159	47.436	97.5	0.463
comX	Streptococcus salivarius SK126	43.226	96.875	0.419
comX/sigX	Streptococcus salivarius strain HSISS4	43.226	96.875	0.419
comX	Streptococcus thermophilus LMG 18311	42.581	96.875	0.413
comX	Streptococcus thermophilus LMD-9	42.581	96.875	0.413
comX	Streptococcus sobrinus strain NIDR 6715-7	42.208	96.25	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.909	96.25	0.394
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.909	96.25	0.394
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.873	98.75	0.394
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40.26	96.25	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40.26	96.25	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40.26	96.25	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40.26	96.25	0.388