Detailed information NTG1120919

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: EL115_RS08635
• Genome accession: NZ_LR134307
• Coordinates: 1722104..1722586 (-)
• Length: 160 a.a.
• NCBI ID: WP_126441034.1
• Uniprot ID: -
• Organism: Streptococcus milleri strain NCTC10708
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1714253..1722586	1722104..1722586	within	0

Gene organization within MGE regions

Location: 1714253..1722586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL115_RS08545	-	1714822..1715190 (+)	369	Protein_1636	type II toxin-antitoxin system RelE/ParE family toxin	-
EL115_RS08550 (NCTC10708_01694)	-	1715177..1715452 (+)	276	WP_003070842.1	helix-turn-helix domain-containing protein	-
EL115_RS08635 (NCTC10708_01711)	comR/comR2	1722104..1722586 (-)	483	WP_126441034.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19797.62 Da
• Isoelectric Point: 7.9710

>NTDB_id=1120919 EL115_RS08635 WP_126441034.1 1722104..1722586(-) (comR/comR2) [Streptococcus milleri strain NCTC10708]
MDFKELYDKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYELVSRYPQLVESESRLYVYYKTKFRNHIKDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQKQLSPEKQEQYERLLADERFQGRQAMLRELRAYLQDYDERKS

Nucleotide

• Length: 483 bp

>NTDB_id=1120919 EL115_RS08635 WP_126441034.1 1722104..1722586(-) (comR/comR2) [Streptococcus milleri strain NCTC10708]
ATGGACTTCAAGGAGTTGTATGACAAAGTGAGAGGGATCGTACTGAAGTGTCGCCGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAAGGGATGCTGGTCTTATATGAGTTGGTGAGTCGCTATCCACAACTGGTAGAGTCAGAAA
GTCGTCTCTATGTTTACTATAAGACCAAGTTCCGTAATCACATCAAGGACATCCTGCGCAAACAAGAAAGCCAAAAGCGC
AAACTAGACCGTCAAGCCTATGAGGAAGTGAGCGAGATAGGTCACAAGCTCAGCCTGAAAGAACTCTATTTGGATGAATT
GGTGATTCTCCGAGACCAACTAAAGAGCTATCAAAAACAGCTAAGTCCAGAGAAACAAGAACAGTATGAGCGCTTACTAG
CAGATGAACGGTTTCAAGGACGCCAAGCGATGCTTCGGGAGTTACGGGCCTACTTACAAGATTACGATGAAAGAAAAAGC
TAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	56.41	97.5	0.55
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	55.769	97.5	0.544
comX/comX2	Streptococcus pneumoniae D39	55.128	97.5	0.537
comX/comX2	Streptococcus pneumoniae R6	55.128	97.5	0.537
comX/comX1	Streptococcus pneumoniae R6	55.128	97.5	0.537
comX/comX1	Streptococcus pneumoniae D39	55.128	97.5	0.537
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	55.128	97.5	0.537
comX/comX2	Streptococcus pneumoniae Rx1	55.128	97.5	0.537
comX/comX1	Streptococcus pneumoniae Rx1	55.128	97.5	0.537
comX/comX2	Streptococcus pneumoniae TIGR4	54.487	97.5	0.531
comX/comX1	Streptococcus pneumoniae TIGR4	54.487	97.5	0.531
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	54.487	97.5	0.531
comX/sigX	Streptococcus mutans UA159	50.318	98.125	0.494
comX/sigX	Streptococcus suis D9	46.452	96.875	0.45
comX/sigX	Streptococcus suis isolate S10	46.452	96.875	0.45
comX/sigX	Streptococcus suis P1/7	46.452	96.875	0.45
comX	Streptococcus salivarius SK126	43.506	96.25	0.419
comX/sigX	Streptococcus salivarius strain HSISS4	42.857	96.25	0.412
comX	Streptococcus thermophilus LMD-9	42.857	96.25	0.412
comX	Streptococcus thermophilus LMG 18311	42.857	96.25	0.412
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.401	98.125	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.401	98.125	0.406
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.401	98.125	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.401	98.125	0.406
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	41.401	98.125	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	41.401	98.125	0.406
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.744	97.5	0.388
comX	Streptococcus sobrinus strain NIDR 6715-7	37.419	96.875	0.362