Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   EL087_RS08395 Genome accession   NZ_LR134288
Coordinates   1705410..1705883 (-) Length   157 a.a.
NCBI ID   WP_022527131.1    Uniprot ID   A0AAN4T6B8
Organism   Streptococcus milleri strain NCTC11169     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1700410..1710883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS08375 (NCTC11169_01728) - 1702109..1702570 (-) 462 WP_037567136.1 CtsR family transcriptional regulator -
  EL087_RS08380 (NCTC11169_01729) - 1702830..1703180 (+) 351 WP_037567137.1 hypothetical protein -
  EL087_RS08385 (NCTC11169_01730) tsf 1703267..1704310 (-) 1044 WP_003041778.1 translation elongation factor Ts -
  EL087_RS08390 (NCTC11169_01731) rpsB 1704394..1705176 (-) 783 WP_022525388.1 30S ribosomal protein S2 -
  EL087_RS08395 (NCTC11169_01732) comR/comR2 1705410..1705883 (-) 474 WP_022527131.1 sigma-70 family RNA polymerase sigma factor Regulator
  EL087_RS08400 (NCTC11169_01734) rplQ 1706292..1706678 (-) 387 WP_126407962.1 50S ribosomal protein L17 -
  EL087_RS08405 (NCTC11169_01735) - 1706690..1707628 (-) 939 WP_003026514.1 DNA-directed RNA polymerase subunit alpha -
  EL087_RS08410 (NCTC11169_01736) rpsK 1707673..1708056 (-) 384 WP_001118385.1 30S ribosomal protein S11 -
  EL087_RS08415 (NCTC11169_01737) rpsM 1708076..1708441 (-) 366 WP_002262317.1 30S ribosomal protein S13 -
  EL087_RS08420 (NCTC11169_01738) rpmJ 1708457..1708573 (-) 117 WP_001808836.1 50S ribosomal protein L36 -
  EL087_RS08425 (NCTC11169_01739) infA 1708598..1708816 (-) 219 WP_001029883.1 translation initiation factor IF-1 -
  EL087_RS08430 (NCTC11169_01740) - 1708932..1709570 (-) 639 WP_003040498.1 adenylate kinase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19282.13 Da        Isoelectric Point: 8.6080

>NTDB_id=1120282 EL087_RS08395 WP_022527131.1 1705410..1705883(-) (comR/comR2) [Streptococcus milleri strain NCTC11169]
MEFKELYAKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYQLVSRYPQLVETESQLYVYYKTKFRNHIKDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=1120282 EL087_RS08395 WP_022527131.1 1705410..1705883(-) (comR/comR2) [Streptococcus milleri strain NCTC11169]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTGCTGAAGTGTCGGAGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGACCAAGAGGGCATGTTAGTACTCTATCAGTTGGTGAGTCGCTATCCGCAGCTGGTAGAGACAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTTCGAAATCACATCAAGGACATCCTCCGCAAACAAGAAAGCCAAAAGCGC
AAGCTGGACCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGTCTAAAAGAACTGTATTTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGTCCAGAGAAACAAGAGCAGTACGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCTATGATTCGAGAATTAAGAGCCTACTTAAAGGACTATAGCGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae D39

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae D39

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae R6

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae R6

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae Rx1

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae Rx1

53.896

98.089

0.529
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae TIGR4

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae TIGR4

53.247

98.089

0.522
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

53.247

98.089

0.522
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

52.597

98.089

0.516
  comX/sigX Streptococcus mutans UA159

49.359

99.363

0.49
  comX/sigX Streptococcus suis D9

48.387

98.726

0.478
  comX/sigX Streptococcus suis isolate S10

48.387

98.726

0.478
  comX/sigX Streptococcus suis P1/7

48.387

98.726

0.478
  comX Streptococcus salivarius SK126

44.156

98.089

0.433
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.949

99.363

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.949

99.363

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.949

99.363

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.949

99.363

0.427
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.949

99.363

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.949

99.363

0.427
  comX/sigX Streptococcus salivarius strain HSISS4

43.506

98.089

0.427
  comX Streptococcus thermophilus LMG 18311

43.506

98.089

0.427
  comX Streptococcus thermophilus LMD-9

43.506

98.089

0.427
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.103

99.363

0.389
  comX Streptococcus sobrinus strain NIDR 6715-7

38.562

97.452

0.376

Multiple sequence alignment