Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   EL087_RS07770 Genome accession   NZ_LR134288
Coordinates   1579365..1579838 (-) Length   157 a.a.
NCBI ID   WP_126407829.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC11169     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1574365..1584838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS07750 (NCTC11169_01604) - 1575319..1576176 (-) 858 WP_126407827.1 DUF6287 domain-containing protein -
  EL087_RS07755 (NCTC11169_01605) - 1576485..1577141 (-) 657 WP_106083798.1 phosphoribosylglycinamide synthetase -
  EL087_RS07760 (NCTC11169_01606) - 1577816..1578286 (-) 471 WP_232008246.1 LacI family DNA-binding transcriptional regulator -
  EL087_RS07765 - 1578353..1579172 (-) 820 Protein_1485 Cof-type HAD-IIB family hydrolase -
  EL087_RS07770 (NCTC11169_01609) comR/comR2 1579365..1579838 (-) 474 WP_126407829.1 sigma-70 family RNA polymerase sigma factor Regulator
  EL087_RS07775 (NCTC11169_01610) nusB 1580034..1580459 (-) 426 WP_003039673.1 transcription antitermination factor NusB -
  EL087_RS07780 (NCTC11169_01611) - 1580452..1580841 (-) 390 WP_003037725.1 Asp23/Gls24 family envelope stress response protein -
  EL087_RS07785 (NCTC11169_01612) efp 1580952..1581512 (-) 561 WP_003037772.1 elongation factor P -
  EL087_RS07790 (NCTC11169_01613) - 1581571..1582632 (-) 1062 WP_126407831.1 M24 family metallopeptidase -
  EL087_RS07795 (NCTC11169_01614) - 1582780..1583535 (+) 756 WP_049513876.1 hypothetical protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19253.09 Da        Isoelectric Point: 7.9719

>NTDB_id=1120279 EL087_RS07770 WP_126407829.1 1579365..1579838(-) (comR/comR2) [Streptococcus milleri strain NCTC11169]
MEFKELYAKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYQLVSRYPQLVETESQLYVYYKTKFRNHILDVLRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=1120279 EL087_RS07770 WP_126407829.1 1579365..1579838(-) (comR/comR2) [Streptococcus milleri strain NCTC11169]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTGTTGAAGTGTCGGAGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGACCAAGAGGGCATGTTGGTGCTCTATCAGTTGGTGAGTCGCTATCCGCAGCTGGTAGAGACAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTGGACGTCCTCCGTAAACAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTACGAACGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCTATGATTCGAGAATTAAGAGCCTACTTAAAAGACTATAGCGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

55.195

98.089

0.541
  comX/comX2 Streptococcus pneumoniae D39

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae D39

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae R6

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae R6

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae Rx1

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae Rx1

54.545

98.089

0.535
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae TIGR4

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae TIGR4

53.896

98.089

0.529
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

53.896

98.089

0.529
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

53.247

98.089

0.522
  comX/sigX Streptococcus mutans UA159

49.359

99.363

0.49
  comX/sigX Streptococcus suis D9

47.742

98.726

0.471
  comX/sigX Streptococcus suis isolate S10

47.742

98.726

0.471
  comX/sigX Streptococcus suis P1/7

47.742

98.726

0.471
  comX Streptococcus salivarius SK126

44.156

98.089

0.433
  comX/sigX Streptococcus salivarius strain HSISS4

43.506

98.089

0.427
  comX Streptococcus thermophilus LMG 18311

43.506

98.089

0.427
  comX Streptococcus thermophilus LMD-9

43.506

98.089

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX Streptococcus sobrinus strain NIDR 6715-7

39.216

97.452

0.382
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.821

99.363

0.376

Multiple sequence alignment