Detailed information NTG1120225

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: EL087_RS00075
• Genome accession: NZ_LR134288
• Coordinates: 15020..15493 (+)
• Length: 157 a.a.
• NCBI ID: WP_126405994.1
• Uniprot ID: -
• Organism: Streptococcus milleri strain NCTC11169
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	16026..16508	15020..15493	flank	533

Gene organization within MGE regions

Location: 15020..16508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL087_RS00075 (NCTC11169_00014)	comR/comR2	15020..15493 (+)	474	WP_126405994.1	sigma-70 family RNA polymerase sigma factor	Regulator
EL087_RS00080	-	15500..16508 (-)	1009	Protein_15	IS30 family transposase	-

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19278.12 Da
• Isoelectric Point: 6.8668

>NTDB_id=1120225 EL087_RS00075 WP_126405994.1 15020..15493(+) (comR/comR2) [Streptococcus milleri strain NCTC11169]
MEFKELYAKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYQLVSCYPQLVEEDHQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide

• Length: 474 bp

>NTDB_id=1120225 EL087_RS00075 WP_126405994.1 15020..15493(+) (comR/comR2) [Streptococcus milleri strain NCTC11169]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTGTTGAAGTGTCGGAGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGACCAAGAGGGCATGTTGGTGCTCTATCAGTTGGTGAGTTGCTATCCGCAGCTAGTAGAAGAAGATC
ATCAGCTTTATGTTTACTATAAGACCAAGTTTCGTAATCATATCTTGGACATCCTCCGTAAGCAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTACGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCCATGATTCGAGAATTAAGAGCCTACTTAAAGGACTATAGCGATTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	60.256	99.363	0.599
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	60.256	99.363	0.599
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	54.545	98.089	0.535
comX/comX2	Streptococcus pneumoniae Rx1	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae Rx1	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae D39	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae D39	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae R6	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae R6	53.896	98.089	0.529
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	53.896	98.089	0.529
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	53.247	98.089	0.522
comX/comX2	Streptococcus pneumoniae TIGR4	53.247	98.089	0.522
comX/comX1	Streptococcus pneumoniae TIGR4	53.247	98.089	0.522
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	53.595	97.452	0.522
comX/sigX	Streptococcus mutans UA159	49.359	99.363	0.49
comX/sigX	Streptococcus suis isolate S10	48.387	98.726	0.478
comX/sigX	Streptococcus suis P1/7	48.387	98.726	0.478
comX/sigX	Streptococcus suis D9	48.387	98.726	0.478
comX	Streptococcus salivarius SK126	44.805	98.089	0.439
comX/sigX	Streptococcus salivarius strain HSISS4	44.156	98.089	0.433
comX	Streptococcus thermophilus LMG 18311	44.156	98.089	0.433
comX	Streptococcus thermophilus LMD-9	44.156	98.089	0.433
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.667	99.363	0.414
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.667	99.363	0.414
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.667	99.363	0.414
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	41.667	99.363	0.414
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	41.667	99.363	0.414
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.667	99.363	0.414
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	37.821	99.363	0.376
comX	Streptococcus sobrinus strain NIDR 6715-7	37.908	97.452	0.369