Detailed information NTG0105980

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AAA985_RS09460
• Genome accession: NZ_AP028603
• Coordinates: 1815985..1817052 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159562.1
• Uniprot ID: B1I897
• Organism: Streptococcus pneumoniae strain Pne2
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1810985..1822052

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA985_RS09445 (TKY181970_18750)	treR	1812782..1813492 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
AAA985_RS09450	-	1813647..1814973 (+)	1327	Protein_1871	ISL3 family transposase	-
AAA985_RS09455 (TKY181970_18790)	amiF	1815048..1815974 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
AAA985_RS09460 (TKY181970_18800)	amiE	1815985..1817052 (-)	1068	WP_000159562.1	ABC transporter ATP-binding protein	Regulator
AAA985_RS09465 (TKY181970_18810)	amiD	1817061..1817987 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
AAA985_RS09470 (TKY181970_18820)	amiC	1817987..1819483 (-)	1497	WP_338168209.1	ABC transporter permease	Regulator
AAA985_RS09475 (TKY181970_18830)	amiA3	1819550..1821529 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=105980 AAA985_RS09460 WP_000159562.1 1815985..1817052(-) (amiE) [Streptococcus pneumoniae strain Pne2]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKEWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=105980 AAA985_RS09460 WP_000159562.1 1815985..1817052(-) (amiE) [Streptococcus pneumoniae strain Pne2]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGAGTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: B1I897

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538