Detailed information NTG1036414

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: ACA346_RS00450
• Genome accession: NZ_CP166970
• Coordinates: 78614..79084 (+)
• Length: 156 a.a.
• NCBI ID: WP_130554428.1
• Uniprot ID: A0A4Q8L355
• Organism: Streptococcus parasuis strain NX1
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	77665..77886	78614..79084	flank	728

Gene organization within MGE regions

Location: 77665..79084

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACA346_RS00440 (ACA346_00440)	-	77713..77853 (+)	141	Protein_67	ISL3 family transposase	-
ACA346_RS00445 (ACA346_00445)	-	77883..78431 (+)	549	WP_418126911.1	nucleotidyltransferase family protein	-
ACA346_RS00450 (ACA346_00450)	comX/sigX	78614..79084 (+)	471	WP_130554428.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 156 a.a.
• Molecular weight: 18995.75 Da
• Isoelectric Point: 7.4572

>NTDB_id=1036414 ACA346_RS00450 WP_130554428.1 78614..79084(+) (comX/sigX) [Streptococcus parasuis strain NX1]
MKFEQTYAKVSGIVHKARQEFYIKLWEKSDWDQEGMMVLYELLEKQPQLYDDKEKLYVYFKVKFRNHIKDVIRKQESYKR
KFDRMAHEDIHDLSHVVKSPGLVNDEFILLQDMLQSYRQQLNSEQLEQYEKLIAGQSFSGRKQMIRDLQDYLADFK

Nucleotide

• Length: 471 bp

>NTDB_id=1036414 ACA346_RS00450 WP_130554428.1 78614..79084(+) (comX/sigX) [Streptococcus parasuis strain NX1]
ATGAAATTTGAACAAACTTACGCAAAGGTTAGTGGTATTGTACATAAGGCTCGTCAAGAATTTTATATCAAGTTATGGGA
AAAGTCAGACTGGGATCAAGAAGGAATGATGGTATTATATGAATTATTAGAAAAACAACCCCAGTTATATGATGATAAAG
AAAAATTATATGTATATTTTAAAGTAAAATTTAGAAATCATATAAAGGATGTTATACGCAAGCAAGAAAGTTACAAAAGA
AAATTTGACAGAATGGCACATGAAGACATCCATGACCTATCCCATGTTGTGAAATCACCTGGACTGGTTAACGATGAATT
TATTCTTCTGCAAGATATGTTACAGTCTTATCGGCAACAGTTAAATTCAGAACAACTAGAGCAATATGAAAAATTGATAG
CAGGGCAGAGTTTTAGTGGCCGAAAACAAATGATTCGTGATTTGCAAGACTATTTAGCAGATTTTAAATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A4Q8L355

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus suis D9	65.385	100	0.654
comX/sigX	Streptococcus suis P1/7	64.744	100	0.647
comX/sigX	Streptococcus suis isolate S10	64.744	100	0.647
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	47.097	99.359	0.468
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	47.097	99.359	0.468
comX/sigX	Streptococcus mutans UA159	46.753	98.718	0.462
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	43.137	98.077	0.423
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	42.484	98.077	0.417
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	41.401	100	0.417
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	41.83	98.077	0.41
comX/comX1	Streptococcus pneumoniae Rx1	42.384	96.795	0.41
comX/comX2	Streptococcus pneumoniae Rx1	42.384	96.795	0.41
comX/comX2	Streptococcus pneumoniae D39	42.384	96.795	0.41
comX/comX1	Streptococcus pneumoniae D39	42.384	96.795	0.41
comX/comX2	Streptococcus pneumoniae R6	42.384	96.795	0.41
comX/comX1	Streptococcus pneumoniae R6	42.384	96.795	0.41
comX/comX1	Streptococcus pneumoniae TIGR4	41.722	96.795	0.404
comX/comX2	Streptococcus pneumoniae TIGR4	41.722	96.795	0.404
comX	Streptococcus salivarius SK126	41.176	98.077	0.404
comX/sigX	Streptococcus salivarius strain HSISS4	41.176	98.077	0.404
comX	Streptococcus sobrinus strain NIDR 6715-7	40.523	98.077	0.397
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	40.523	98.077	0.397
comX	Streptococcus thermophilus LMG 18311	40.523	98.077	0.397
comX	Streptococcus thermophilus LMD-9	40.523	98.077	0.397
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	96.154	0.385
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40	96.154	0.385
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	96.154	0.385
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	96.154	0.385
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	96.154	0.385
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40	96.154	0.385