Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   FGL00_RS01840 Genome accession   NZ_LR594034
Coordinates   349484..349966 (+) Length   160 a.a.
NCBI ID   WP_003057148.1    Uniprot ID   A0A9X9GB62
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 344484..354966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL00_RS01840 (NCTC8546_00380) comX/sigX/comX2/sigX2 349484..349966 (+) 483 WP_003057148.1 sigma-70 family RNA polymerase sigma factor Regulator
  FGL00_RS01845 (NCTC8546_00381) - 350097..351092 (-) 996 WP_138083698.1 IS30 family transposase -
  FGL00_RS01850 (NCTC8546_00382) - 351297..351824 (+) 528 WP_015057333.1 YqeG family HAD IIIA-type phosphatase -
  FGL00_RS01855 (NCTC8546_00383) yqeH 351824..352942 (+) 1119 WP_002985994.1 ribosome biogenesis GTPase YqeH -
  FGL00_RS01860 (NCTC8546_00384) yhbY 352968..353276 (+) 309 WP_046159301.1 ribosome assembly RNA-binding protein YhbY -
  FGL00_RS01865 (NCTC8546_00385) - 353345..353977 (+) 633 WP_138098240.1 nicotinate-nucleotide adenylyltransferase -
  FGL00_RS01870 (NCTC8546_00386) yqeK 353974..354567 (+) 594 WP_003055753.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  FGL00_RS01875 (NCTC8546_00387) - 354543..354803 (+) 261 WP_011528257.1 isochorismatase family protein -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18997.80 Da        Isoelectric Point: 8.3220

>NTDB_id=1004912 FGL00_RS01840 WP_003057148.1 349484..349966(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MSLETGEVFEKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVKLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQ
KRQFDKMAYEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSEADRKQFQALVRGERFKGRQALLRKVRPYFSGFDQG

Nucleotide


Download         Length: 483 bp        

>NTDB_id=1004912 FGL00_RS01840 WP_003057148.1 349484..349966(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGTCGTTAGAGACAGGGGAGGTTTTTGAGAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACTTACAGTT
GTGGGAGACGGATGACTGGTTACAAGAGGGGCATTTGGTTTTAGTGAAGTTGTTGGAACGTCACCCAGAGTTAGTAGGAG
ATGAGGCTCGCTTGTATCGGTATTTTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAG
AAACGCCAGTTTGACAAGATGGCTTATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGCGGGTTATGGTTGGA
TGATTATGTGGCCTATCGGGAGGTTTTAGTACAAGTGGAGGAGGCCTTAAGCGAAGCGGATCGGAAGCAGTTTCAGGCCT
TAGTGAGAGGGGAACGGTTCAAGGGGCGTCAGGCTTTGCTTAGGAAGGTTCGTCCTTACTTTAGTGGGTTTGACCAAGGG
TGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9GB62

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

74.843

99.375

0.744
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

74.843

99.375

0.744
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

74.214

99.375

0.738
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

74.214

99.375

0.738
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

73.585

99.375

0.731
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

73.585

99.375

0.731
  comX/sigX Streptococcus mutans UA159

50

93.75

0.469
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

93.75

0.456
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

46.711

95

0.444
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.395

95

0.431
  comX/comX1 Streptococcus pneumoniae Rx1

45.033

94.375

0.425
  comX/comX2 Streptococcus pneumoniae TIGR4

45.033

94.375

0.425
  comX/comX1 Streptococcus pneumoniae TIGR4

45.033

94.375

0.425
  comX/comX2 Streptococcus pneumoniae Rx1

45.033

94.375

0.425
  comX/comX2 Streptococcus pneumoniae D39

45.033

94.375

0.425
  comX/comX1 Streptococcus pneumoniae D39

45.033

94.375

0.425
  comX/comX2 Streptococcus pneumoniae R6

45.033

94.375

0.425
  comX/comX1 Streptococcus pneumoniae R6

45.033

94.375

0.425
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

44.079

95

0.419
  comX Streptococcus sobrinus strain NIDR 6715-7

44.079

95

0.419
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419
  comX Streptococcus thermophilus LMG 18311

43.709

94.375

0.413
  comX Streptococcus thermophilus LMD-9

43.709

94.375

0.413
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.421

95

0.412
  comX/sigX Streptococcus salivarius strain HSISS4

41.722

94.375

0.394
  comX Streptococcus salivarius SK126

41.722

94.375

0.394
  comX/sigX Streptococcus suis D9

38.71

96.875

0.375
  comX/sigX Streptococcus suis isolate S10

38.71

96.875

0.375
  comX/sigX Streptococcus suis P1/7

38.71

96.875

0.375

Multiple sequence alignment