Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS01037 insolico
T6SS type Type i1
Strain Dickeya zeae EC1
Replicon (RefSeq) chromosome (NZ_CP006929)
Location 1386995..1407270
Function -
Comment Transcriptome analysis showed that T6SS was the most affected secretion system, with reductions in the ΔvfmH mutant ranging from 6.6 to 1196.9 fold.
References
[1] Lv M, Hu M, Li P, Jiang Z, Zhang LH, Zhou J. et al (2019) A two-component regulatory system VfmIH modulates multiple virulence traits in Dickeya zeae.. Mol Microbiol. 111(6):1493-1509. [PudMed:30825339]
insolico Bioinformatics investigation has been performed.

T6SS components and genome coordinates

ComponentTssATssBTssCTssETssFTssGTssHTssJTssKTssLTssM
Number21111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
W909_RS06325 1382361..1382708 + 348 WP_016943503.1 hypothetical protein
W909_RS06330 1382770..1383114 - 345 WP_016943504.1 SymE family type I addiction module toxin
W909_RS06335 1383111..1383409 - 299 pseudogene type I toxin-antitoxin system SymE family toxin
W909_RS06340 1383498..1383770 + 273 WP_016943505.1 type II toxin-antitoxin system ParD family antitoxin
W909_RS06345 1383770..1384090 + 321 WP_016943506.1 type II toxin-antitoxin system RelE/ParE family toxin
W909_RS20780 1384233..1384400 - 168 WP_016943507.1 hypothetical protein
W909_RS06350 1384716..1385873 + 1158 WP_016943508.1 amidohydrolase
T6CP013442 TssB W909_RS06355 (tssB) 1386995..1387498 + 504 WP_012770486.1 type VI secretion system contractile sheath small subunit
T6CP013443 TssC W909_RS06360 (tssC) 1387530..1389008 + 1479 WP_012884008.1 type VI secretion system contractile sheath large subunit
T6CP013444 TssE W909_RS06365 (tssE) 1389015..1389446 + 432 WP_012770484.1 type VI secretion system baseplate subunit TssE
T6CP013445 TssF W909_RS06370 (tssF) 1389449..1391215 + 1767 WP_016943509.1 type VI secretion system baseplate subunit TssF
T6CP013446 TssG W909_RS06375 (tssG) 1391179..1392192 + 1014 WP_012884010.1 type VI secretion system baseplate subunit TssG
W909_RS06380 (tagH) 1392195..1393424 + 1230 WP_029456596.1 type VI secretion system-associated FHA domain protein TagH
T6CP013447 TssJ W909_RS06385 (tssJ) 1393424..1393960 + 537 WP_016943512.1 type VI secretion system lipoprotein TssJ
T6CP013448 TssK W909_RS06390 (tssK) 1393963..1395300 + 1338 WP_012884013.1 type VI secretion system baseplate subunit TssK
T6CP013449 TssL W909_RS06395 (icmH) 1395317..1396093 + 777 WP_012884014.1 type IVB secretion system protein IcmH/DotU
T6CP013450 TssH W909_RS06400 (tssH) 1396109..1398709 + 2601 WP_016943513.1 type VI secretion system ATPase TssH
W909_RS06405 1398712..1400250 + 1539 WP_016943514.1 sigma-54 dependent transcriptional regulator
W909_RS06410 (tagO) 1400250..1400813 + 564 WP_029456598.1 type VI secretion system-associated protein TagO
T6CP013451 TssA W909_RS06415 (tssA) 1400825..1402261 + 1437 WP_029456599.1 type VI secretion system protein TssA
T6CP013452 TssM W909_RS06420 (tssM) 1402287..1405784 + 3498 WP_016943517.1 type VI secretion system membrane subunit TssM
T6CP013453 TssA W909_RS06425 1405837..1407270 + 1434 WP_016943518.1 type VI secretion system ImpA family N-terminal domain-containing protein
W909_RS06430 1407383..1408753 + 1371 WP_016943519.1 sel1 repeat family protein
W909_RS06435 1408797..1409732 + 936 WP_029456601.1 DKNYY domain-containing protein
W909_RS06440 1409799..1410659 - 861 WP_016943521.1 D-amino-acid transaminase
W909_RS06445 1410659..1411669 - 1011 WP_016943522.1 dipeptide epimerase
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0356 experimental W909_RS11820 (VfmH) protein TCS-RR Dickeya zeae EC1 chromosome (NZ_CP006929) 2699617..2701098 (+) 515507611 T6SS transcripts (↓)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector