Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01037  |
| T6SS type | Type i1 |
| Strain | Dickeya zeae EC1 |
| Replicon (RefSeq) | chromosome (NZ_CP006929) |
| Location | 1386995..1407270 |
| Function | - |
| Comment | Transcriptome analysis showed that T6SS was the most affected secretion system, with reductions in the ΔvfmH mutant ranging from 6.6 to 1196.9 fold. |
| References | [1] Lv M, Hu M, Li P, Jiang Z, Zhang LH, Zhou J. et al (2019) A two-component regulatory system VfmIH modulates multiple virulence traits in Dickeya zeae.. Mol Microbiol. 111(6):1493-1509. [PudMed:30825339] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| W909_RS06325 | 1382361..1382708 | + | 348 | WP_016943503.1 | hypothetical protein | ||
| W909_RS06330 | 1382770..1383114 | - | 345 | WP_016943504.1 | SymE family type I addiction module toxin | ||
| W909_RS06335 | 1383111..1383409 | - | 299 | pseudogene | type I toxin-antitoxin system SymE family toxin | ||
| W909_RS06340 | 1383498..1383770 | + | 273 | WP_016943505.1 | type II toxin-antitoxin system ParD family antitoxin | ||
| W909_RS06345 | 1383770..1384090 | + | 321 | WP_016943506.1 | type II toxin-antitoxin system RelE/ParE family toxin | ||
| W909_RS20780 | 1384233..1384400 | - | 168 | WP_016943507.1 | hypothetical protein | ||
| W909_RS06350 | 1384716..1385873 | + | 1158 | WP_016943508.1 | amidohydrolase | ||
| T6CP013442 | TssB | W909_RS06355 (tssB) | 1386995..1387498 | + | 504 | WP_012770486.1 | type VI secretion system contractile sheath small subunit |
| T6CP013443 | TssC | W909_RS06360 (tssC) | 1387530..1389008 | + | 1479 | WP_012884008.1 | type VI secretion system contractile sheath large subunit |
| T6CP013444 | TssE | W909_RS06365 (tssE) | 1389015..1389446 | + | 432 | WP_012770484.1 | type VI secretion system baseplate subunit TssE |
| T6CP013445 | TssF | W909_RS06370 (tssF) | 1389449..1391215 | + | 1767 | WP_016943509.1 | type VI secretion system baseplate subunit TssF |
| T6CP013446 | TssG | W909_RS06375 (tssG) | 1391179..1392192 | + | 1014 | WP_012884010.1 | type VI secretion system baseplate subunit TssG |
| W909_RS06380 (tagH) | 1392195..1393424 | + | 1230 | WP_029456596.1 | type VI secretion system-associated FHA domain protein TagH | ||
| T6CP013447 | TssJ | W909_RS06385 (tssJ) | 1393424..1393960 | + | 537 | WP_016943512.1 | type VI secretion system lipoprotein TssJ |
| T6CP013448 | TssK | W909_RS06390 (tssK) | 1393963..1395300 | + | 1338 | WP_012884013.1 | type VI secretion system baseplate subunit TssK |
| T6CP013449 | TssL | W909_RS06395 (icmH) | 1395317..1396093 | + | 777 | WP_012884014.1 | type IVB secretion system protein IcmH/DotU |
| T6CP013450 | TssH | W909_RS06400 (tssH) | 1396109..1398709 | + | 2601 | WP_016943513.1 | type VI secretion system ATPase TssH |
| W909_RS06405 | 1398712..1400250 | + | 1539 | WP_016943514.1 | sigma-54 dependent transcriptional regulator | ||
| W909_RS06410 (tagO) | 1400250..1400813 | + | 564 | WP_029456598.1 | type VI secretion system-associated protein TagO | ||
| T6CP013451 | TssA | W909_RS06415 (tssA) | 1400825..1402261 | + | 1437 | WP_029456599.1 | type VI secretion system protein TssA |
| T6CP013452 | TssM | W909_RS06420 (tssM) | 1402287..1405784 | + | 3498 | WP_016943517.1 | type VI secretion system membrane subunit TssM |
| T6CP013453 | TssA | W909_RS06425 | 1405837..1407270 | + | 1434 | WP_016943518.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| W909_RS06430 | 1407383..1408753 | + | 1371 | WP_016943519.1 | sel1 repeat family protein | ||
| W909_RS06435 | 1408797..1409732 | + | 936 | WP_029456601.1 | DKNYY domain-containing protein | ||
| W909_RS06440 | 1409799..1410659 | - | 861 | WP_016943521.1 | D-amino-acid transaminase | ||
| W909_RS06445 | 1410659..1411669 | - | 1011 | WP_016943522.1 | dipeptide epimerase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0356 |
W909_RS11820 (VfmH) | protein | TCS-RR | Dickeya zeae EC1 | chromosome (NZ_CP006929) | 2699617..2701098 (+) | 515507611 | T6SS transcripts (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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