Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00928  |
| T6SS type | Type i1 |
| Strain | Campylobacter jejuni 108 |
| Replicon (GenBank) | chromosome (JX436460) |
| Location | 1..17012 |
| Function | anti-eukaryotic |
| Comment | C. jejuni T6SS confers contact-dependent cytotoxicity towards red blood cells but not macrophages; Colonisation of mouse; adhesion to and invasion of cultured colonic epithelial cells. |
| References | [1] Bleumink-Pluym NM et al (2013) Identification of a Functional Type VI Secretion System in Campylobacter jejuni Conferring Capsule Polysaccharide Sensitive Cytotoxicity. PLoS Pathog. 9(5):e1003393. [PudMed:23737749] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| T6CP012924 | FHA | Locus_01 | 1..900 | - | 900 | 510027015 | TagH |
| T6CP012912 | TssM | Locus_02 | 897..4424 | - | 3528 | 510027003 | TssM |
| T6CP012913 | TssD | Locus_03 | 4542..5057 | + | 516 | 510027004 | TssD |
| T6CP012914 | TssL | Locus_04 | 5312..6085 | - | 774 | 510027005 | TssL |
| T6CP012915 | TssK | Locus_05 | 6082..7479 | - | 1398 | 510027006 | TssK |
| T6CP012916 | TssJ | Locus_06 | 7489..7935 | - | 447 | 510027007 | TssJ |
| T6CP012917 | TssA | Locus_07 | 8061..9308 | + | 1248 | 510027008 | TssA |
| T6CP012918 | TssB | Locus_08 | 9377..9862 | + | 486 | 510027009 | TssB |
| T6CP012919 | TssC | Locus_09 | 9864..11318 | + | 1455 | 510027010 | TssC |
| T6CP012920 | TssE | Locus_10 | 11321..11713 | + | 393 | 510027011 | TssE |
| T6CP012921 | TssF | Locus_11 | 11710..13431 | + | 1722 | 510027012 | TssF |
| T6CP012922 | TssG | Locus_12 | 13428..14336 | + | 909 | 510027013 | TssG |
| T6CP012923 | TssI | Locus_13 | 14486..17002 | + | 2517 | 510027014 | TssI |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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