Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00612 insolico
T6SS type Type i4a
Strain Pseudomonas aeruginosa M18
Replicon (RefSeq) chromosome (NC_017548)
Location 2967324..2986402
Function -
Comment -
References
[1] Wei X et al (2013) Global control of GacA on secondary metabolism, primary metabolism, secretion systems, and motility in the rhizobacterium Pseudomonas aeruginosa M18. J Bacteriol. 195(15):3387-400. [PudMed:23708134]
insolico Bioinformatics investigation has been performed.

T6SS components and genome coordinates

ComponentSfa3TssATssBTssCTssDTssETssFTssGTssHTssITssKTssLTssM
Number1111111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
PAM18_RS13700 2964035..2965240 - 1206 WP_023116102.1 ABC transporter substrate-binding protein
PAM18_RS13705 2965441..2966082 - 642 WP_003110901.1 response regulator transcription factor
PAM18_RS13710 2966359..2966754 + 396 WP_003089513.1 DUF4280 domain-containing protein
PAM18_RS13715 2966777..2967313 - 537 WP_003104933.1 toxin-antitoxin system YwqK family antitoxin
T6CP006453 TssI PAM18_RS13720 (tssI) 2967324..2969330 - 2007 WP_014602899.1 type VI secretion system tip protein VgrG
PAM18_RS13725 2969330..2969518 - 189 WP_003104930.1 hypothetical protein
PAM18_RS13730 2969678..2970250 - 573 WP_003122693.1 hypothetical protein
T6CP006454 TssH PAM18_RS13735 (tssH) 2970272..2972821 - 2550 WP_003104929.1 type VI secretion system ATPase TssH
T6CP006455 TssG PAM18_RS13740 (tssG) 2972823..2973839 - 1017 WP_003124579.1 type VI secretion system baseplate subunit TssG
T6CP006456 TssF PAM18_RS13745 (tssF) 2973803..2975596 - 1794 WP_014602900.1 type VI secretion system baseplate subunit TssF
T6CP009049 TssE PAM18_RS13750 (tssE) 2975580..2976005 - 426 WP_014602901.1 type VI secretion system baseplate subunit TssE
T6CP006457 TssD PAM18_RS13755 2976018..2976515 - 498 WP_003089495.1 type VI secretion system tube protein Hcp
T6CP006458 TssC PAM18_RS13760 (tssC) 2976589..2978073 - 1485 WP_003089494.1 type VI secretion system contractile sheath large subunit
T6CP006459 TssB PAM18_RS13765 (tssB) 2978096..2978641 - 546 WP_003089493.1 type VI secretion system contractile sheath small subunit
PAM18_RS13770 2978850..2979326 + 477 WP_003124582.1 hypothetical protein
T6CP006460 TssK PAM18_RS13775 (tssK) 2979386..2980717 + 1332 WP_003124583.1 type VI secretion system baseplate subunit TssK
T6CP009050 TssL PAM18_RS13780 2980735..2981493 + 759 WP_003104706.1 DotU family type IV/VI secretion system protein
T6CP006461 TssM PAM18_RS13785 2981490..2985305 + 3816 WP_014602902.1 hypothetical protein
T6CP006462 TssA PAM18_RS13790 (tssA) 2985302..2986402 + 1101 WP_014602903.1 type VI secretion system protein TssA
T6CP012534 Sfa3 PAM18_RS13795 2986512..2987597 + 1086 WP_012614153.1 sigma-54-dependent transcriptional regulator
PAM18_RS13800 2987833..2988099 + 267 WP_003104712.1 hypothetical protein
PAM18_RS13805 (msuE) 2988259..2988819 + 561 WP_003089470.1 FMN reductase
PAM18_RS13810 (ssuD) 2988829..2989974 + 1146 WP_003104713.1 FMNH2-dependent alkanesulfonate monooxygenase
PAM18_RS13815 2990004..2991188 + 1185 WP_003104714.1 FMNH2-dependent monooxygenase
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0253 experimental PAM18_RS12360 (gacA) protein TCS-RR Pseudomonas aeruginosa M18 chromosome (NC_017548) 2625815..2626459 (+) 489180874 hsiA1 operon transcript (↓); hsiA2 operon transcript (↓); hsiA3 operon transcript (↓)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector