SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP006458
Component protein type	TssC
T6SS ID (Type)	T6SS00612 (Type i4a)
Strain	Pseudomonas aeruginosa M18
Replicon	chromosome
Sequence	Protein sequence (495 a.a.); Nucleotide sequence (1485 bp)
Reference	[1] Wei X, Huang X, Tang L, et al. Global control of GacA in secondary metabolism, primary metabolism, secretion systems, and motility in the rhizobacterium Pseudomonas aeruginosa M18. J Bacteriol. 2013 Aug;195(15):3387-400. doi: 10.1128/JB.00214-13. Epub 2013 May 24. PMID: 23708134

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	PAM18_RS13760
Coordinate (Strand)	2976589..2978073 (-)
NCBI ID	WP_003089494.1
RefSeq	NC_017548
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
VipB	PF05943.14	1.8e-137	68..368
VipB_2	PF18945.2	8.4e-46	377..488

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 495 a.a.

						>T6CP006458 NC_017548:c2978073-2976589 [Pseudomonas aeruginosa M18] [TssC]
MPKSSAAEQSGESSTQTLSLLDEIIAKGRMAHDDSQQDYARDMLAEFATQVLDEGMAVDKDTVAMINDRISQIDALISDQ
LNQIIHHPELQKLEASWRGLHQLVSNTETSARLKLRLLNVGKNELQNDLEKAVEFDQSALFKKIYEEEYGTFGGHPFSLL
IGDFTFGRHPQDIGLLEKLSNVAAAAHAPFIAAASPRLFDMNSFTELAVPRDLTKIFESLELIKWRAFRESEDSRYVSLV
LPNFLLRLPYGPETRPVEGMNYVEDVNGTDHSKYLWGNAAWVLAQRITEAFAKYGWCAAIRGAEGGGAVEGLPAHTFRTS
SGDLSLKCPTEVAITDRREKELNDLGFISLCHKKNSDVAVFFGGQTTNKARLYNTNEANANARLSAMLPYVLAASRFAHY
LKVIMRDKVGSFMTRDNVQTYLNNWIADYVLINDNAPQEIKAQYPLREARVDVSEVAGKPGAYRATVFLRPHFQLEELSA
SIRLVANLPPPVAA*					

Nucleotide sequence: 1485 bp

						>T6CP006458 NC_017548:c2978073-2976589 [Pseudomonas aeruginosa M18] [TssC]
ATGCCCAAGTCATCCGCCGCCGAACAATCCGGCGAGAGTTCGACCCAGACCCTGTCCCTGCTCGACGAGATCATCGCCAA
GGGCCGCATGGCCCACGACGACAGCCAGCAGGACTATGCCCGCGACATGCTCGCGGAATTCGCCACCCAGGTCCTCGACG
AGGGCATGGCCGTCGACAAGGACACCGTGGCGATGATCAACGACCGCATCAGCCAGATCGATGCGCTGATCAGCGACCAG
CTCAACCAGATCATCCACCACCCCGAGTTGCAGAAGCTGGAAGCCTCCTGGCGCGGCCTGCACCAACTGGTGAGCAACAC
CGAGACCAGCGCGCGGCTCAAGCTGCGCCTGCTGAACGTCGGCAAGAACGAACTGCAGAACGACCTGGAGAAGGCGGTCG
AGTTCGACCAGAGCGCACTGTTCAAGAAGATCTACGAAGAGGAATACGGCACCTTCGGCGGACACCCCTTCAGCCTGCTG
ATCGGCGACTTCACCTTCGGTCGCCATCCGCAGGACATCGGCCTGCTGGAGAAGCTGTCGAACGTCGCCGCGGCTGCCCA
CGCGCCGTTCATCGCCGCCGCCAGCCCACGCCTGTTCGACATGAACAGCTTCACCGAACTGGCCGTGCCGCGCGACCTGA
CCAAGATCTTCGAGAGCCTGGAGCTGATCAAGTGGCGCGCCTTCCGCGAGAGCGAGGACTCGCGCTACGTGTCGCTGGTG
CTGCCGAACTTCCTCTTGCGCCTGCCCTACGGCCCGGAGACGCGACCGGTGGAAGGCATGAACTATGTCGAGGACGTCAA
CGGCACCGACCACTCCAAGTACCTCTGGGGCAACGCCGCCTGGGTCCTGGCGCAGCGCATCACCGAGGCCTTCGCCAAGT
ACGGCTGGTGCGCGGCGATCCGCGGCGCGGAAGGCGGCGGCGCGGTCGAGGGGCTGCCGGCGCACACGTTCCGCACCAGC
TCCGGCGACCTGTCGCTGAAGTGCCCGACCGAGGTGGCGATCACCGACCGCCGCGAGAAGGAACTCAACGATCTCGGCTT
CATTTCCCTGTGCCACAAGAAGAACAGCGACGTGGCGGTGTTCTTCGGCGGCCAGACCACCAACAAGGCCAGGCTCTACA
ACACCAACGAGGCCAACGCCAACGCGCGCCTGTCGGCGATGCTGCCGTACGTGCTGGCGGCATCGCGCTTCGCCCACTAC
CTGAAGGTGATCATGCGCGACAAGGTCGGCAGCTTCATGACCCGCGACAACGTGCAGACCTACCTGAACAACTGGATCGC
CGACTACGTGCTGATCAACGACAACGCACCGCAGGAAATCAAGGCGCAGTACCCGCTGCGCGAGGCGCGGGTGGATGTCA
GCGAGGTGGCCGGCAAACCGGGGGCCTACCGCGCCACGGTGTTCCTCCGGCCGCACTTCCAGCTCGAGGAACTCAGCGCG
TCGATCCGCCTGGTCGCCAACCTGCCGCCGCCGGTAGCGGCGTGA					