Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00396  |
| T6SS type | Type i2 |
| Strain | Enterobacter cloacae subsp. cloacae ATCC 13047 |
| Replicon (RefSeq) | chromosome (NC_014121) |
| Location | 1819466..1844686 |
| Function | anti-bacterial; anti-eukaryotic |
| Comment | T6SS-2 is implicated in biofilm formation and adherence to epithelial cells. Both T6SSs are required for intestinal colonization. |
| References | [1] Soria-Bustos J, Ares MA, G��mez-Aldapa CA, Gonz��lez-Y-Merchand JA, Gir��n JA, De la Cruz MA. et al (2020) Two Type VI Secretion Systems of Enterobacter cloacae Are Required for Bacterial Competition, Cell Adherence, and Intestinal Colonization.. Front Microbiol. 11:560488. [PudMed:33072020] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagL | TssA | TssB | TssC | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| ECL_RS08855 (tpx) | 1814799..1815305 | - | 507 | WP_013096423.1 | thiol peroxidase | ||
| ECL_RS08860 (ycjG) | 1815413..1816378 | + | 966 | WP_013096424.1 | L-Ala-D/L-Glu epimerase | ||
| ECL_RS08865 (mpaA) | 1816369..1817082 | - | 714 | WP_013096425.1 | murein tripeptide amidase MpaA | ||
| ECL_RS08870 | 1817265..1818881 | + | 1617 | WP_013096426.1 | peptide ABC transporter substrate-binding protein | ||
| T6CP004069 | TssB | ECL_RS08875 (tssB) | 1819466..1819957 | + | 492 | WP_013096428.1 | type VI secretion system contractile sheath small subunit |
| T6CP004070 | TssC | ECL_RS08880 (tssC) | 1819999..1821540 | + | 1542 | WP_044159362.1 | type VI secretion system contractile sheath large subunit |
| T6CP004071 | TssK | ECL_RS08885 (tssK) | 1821558..1822898 | + | 1341 | WP_013096430.1 | type VI secretion system baseplate subunit TssK |
| T6CP009321 | TssL | ECL_RS08890 (tssL) | 1822895..1823587 | + | 693 | WP_013096431.1 | type VI secretion system protein TssL, short form |
| ECL_RS08895 | 1823584..1825056 | + | 1473 | pseudogene | OmpA family protein | ||
| T6CP004072 | TssH | ECL_RS08900 (tssH) | 1825083..1827341 | + | 2259 | pseudogene | type VI secretion system ATPase TssH |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||